Marcel Faber Roundtable: is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration?
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The Sound of Silence: Activating Silent Biosynthetic Gene Clusters in Marine MicroorganismsLessons learned from the transformation of natural product discovery to a genome-driven endeavorStructure, Bioactivity, and Resistance Mechanism of Streptomonomicin, an Unusual Lasso Peptide from an Understudied Halophilic ActinomyceteSynthesis and Characterization of the Arylomycin Lipoglycopeptide Antibiotics and the Crystallographic Analysis of Their Complex with Signal PeptidaseAntibiotics for emerging pathogensOrigins and evolution of antibiotic resistanceRare actinomycete bacteria from the shallow water sediments of the Trondheim fjord, Norway: isolation, diversity and biological activity.A trap for in situ cultivation of filamentous actinobacteriaIsolation, diversity, and antimicrobial activity of rare actinobacteria from medicinal plants of tropical rain forests in Xishuangbanna, China.Metabolic potential of endophytic bacteria.Sequence-based analysis of secondary-metabolite biosynthesis in marine actinobacteriaChallenges of antibacterial discoveryMarine Rare Actinobacteria: Isolation, Characterization, and Strategies for Harnessing Bioactive Compounds.Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites.Structural investigation of ribosomally synthesized natural products by hypothetical structure enumeration and evaluation using tandem MS.Natural products version 2.0: connecting genes to molecules.The garden of antimicrobial delightsDiversity analysis of streptomycetes and associated phosphotranspherase genes in soilBroad-spectrum antibiotic activity of the arylomycin natural products is masked by natural target mutationsSystems-level antimicrobial drug and drug synergy discovery.Proteomic analysis of polyketide and nonribosomal peptide biosynthesisIdentifying producers of antibacterial compounds by screening for antibiotic resistance.Culturable rare Actinomycetes: diversity, isolation and marine natural product discovery.Synthesis and biological characterization of arylomycin B antibioticsInitial efforts toward the optimization of arylomycins for antibiotic activity.Isolation, abundance and phylogenetic affiliation of endophytic actinomycetes associated with medicinal plants and screening for their in vitro antimicrobial biosynthetic potential.Culturable diversity and antimicrobial activity of Actinobacteria from marine sediments in Valparaíso bay, Chile.Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes.Platensimycin and platencin: Inspirations for chemistry, biology, enzymology, and medicine.Activity-Independent Discovery of Secondary Metabolites Using Chemical Elicitation and Cheminformatic InferenceIn Vitro CRISPR/Cas9 System for Efficient Targeted DNA Editing.Taxonomy, Physiology, and Natural Products of Actinobacteria.David and Goliath: chemical perturbation of eukaryotes by bacteria.Screening for Expressed Nonribosomal Peptide Synthetases and Polyketide Synthases Using LC-MS/MS-Based Proteomics.Revealing nature's synthetic potential through the study of ribosomal natural product biosynthesis."Head-to-side-chain" cyclodepsipeptides of marine origin.Targeted Treatment for Bacterial Infections: Prospects for Pathogen-Specific Antibiotics Coupled with Rapid DiagnosticsSmall and lethal: searching for new antibacterial compounds with novel modes of action.Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A.Antibiotics from microbes: converging to kill.
P2860
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P2860
Marcel Faber Roundtable: is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration?
description
2006 nî lūn-bûn
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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2006 թվականի հունվարին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
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name
Marcel Faber Roundtable: is ou ...... pation or lack of inspiration?
@ast
Marcel Faber Roundtable: is ou ...... pation or lack of inspiration?
@en
type
label
Marcel Faber Roundtable: is ou ...... pation or lack of inspiration?
@ast
Marcel Faber Roundtable: is ou ...... pation or lack of inspiration?
@en
prefLabel
Marcel Faber Roundtable: is ou ...... pation or lack of inspiration?
@ast
Marcel Faber Roundtable: is ou ...... pation or lack of inspiration?
@en
P1476
Marcel Faber Roundtable: is ou ...... pation or lack of inspiration?
@en
P2093
Richard H Baltz
P304
P356
10.1007/S10295-005-0077-9
P577
2006-01-18T00:00:00Z