Genes specific for the biosynthesis of clavam metabolites antipodal to clavulanic acid are clustered with the gene for clavaminate synthase 1 in Streptomyces clavuligerus

Genes specific for the biosynthesis of clavam metabolites antipodal to clavulanic acid are clustered with the gene for clavaminate synthase 1 in Streptomyces clavuligerus

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http://www.wikidata.org/entity/Q33976323
The paralogous pairs of genes involved in clavulanic acid and clavam metabolite biosynthesis are differently regulated in Streptomyces clavuligerusTwo sets of paralogous genes encode the enzymes involved in the early stages of clavulanic acid and clavam metabolite biosynthesis in Streptomyces clavuligerusSynergy and contingency as driving forces for the evolution of multiple secondary metabolite production by Streptomyces speciesEnzymes catalyzing the early steps of clavulanic acid biosynthesis are encoded by two sets of paralogous genes in Streptomyces clavuligerusApplications of gene replacement technology to Streptomyces clavuligerus strain development for clavulanic acid production.Expansion of the clavulanic acid gene cluster: identification and in vivo functional analysis of three new genes required for biosynthesis of clavulanic acid by Streptomyces clavuligerus.Proteomic changes in the base of chrysanthemum cuttings during adventitious root formation.Streptomyces clavuligerus has a second copy of the proclavaminate amidinohydrolase gene.Alanylclavam biosynthetic genes are clustered together with one group of clavulanic acid biosynthetic genes in Streptomyces clavuligerus.Mutants of Streptomyces clavuligerus with disruptions in different genes for clavulanic acid biosynthesis produce large amounts of holomycin: possible cross-regulation of two unrelated secondary metabolic pathways.Five additional genes are involved in clavulanic acid biosynthesis in Streptomyces clavuligerus.Two oligopeptide-permease-encoding genes in the clavulanic acid cluster of Streptomyces clavuligerus are essential for production of the beta-lactamase inhibitor.5S clavam biosynthesis is controlled by an atypical two-component regulatory system in Streptomyces clavuligeruspcd mutants of Streptomyces clavuligerus still produce cephamycin C.
P2860

Genes specific for the biosynthesis of clavam metabolites antipodal to clavulanic acid are clustered with the gene for clavaminate synthase 1 in Streptomyces clavuligerus

Item
http://www.wikidata.org/entity/Q33976323
description
1999 nî lūn-bûn
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1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
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1999 թվականի մայիսին հրատարակված գիտական հոդված
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1999年の論文
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1999年学术文章
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1999年学术文章
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1999年学术文章
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1999年学术文章
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1999年学术文章
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1999年學術文章
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name
Genes specific for the biosynt ...... 1 in Streptomyces clavuligerus
@ast
Genes specific for the biosynt ...... 1 in Streptomyces clavuligerus
@en
type
label
Genes specific for the biosynt ...... 1 in Streptomyces clavuligerus
@ast
Genes specific for the biosynt ...... 1 in Streptomyces clavuligerus
@en
prefLabel
Genes specific for the biosynt ...... 1 in Streptomyces clavuligerus
@ast
Genes specific for the biosynt ...... 1 in Streptomyces clavuligerus
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Genes specific for the biosynt ...... 1 in Streptomyces clavuligerus
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932