about
Main roads to melanomaThe DNA sequence and comparative analysis of human chromosome 10Ubiquitination regulates PTEN nuclear import and tumor suppressionCancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein functionA comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromesPTEN function: how normal cells control it and tumour cells lose itProtean PTEN: form and functionA novel germline mutation of PTEN associated with brain tumours of multiple lineagesMicroRNAs as growth regulators, their function and biomarker status in colorectal cancerThe PTEN tumor suppressor gene and its role in lymphoma pathogenesisRedox Regulation in Cancer Stem CellsTC21 mediates transformation and cell survival via activation of phosphatidylinositol 3-kinase/Akt and NF-kappaB signaling pathwaySuperdomains in the protein structure hierarchy: The case of PTP-C2Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functionsNuclear PTEN levels and G2 progression in melanoma cellsNuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifsPI3K/AKT pathway mutations cause a spectrum of brain malformations from megalencephaly to focal cortical dysplasiaStructural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancerEvidence of ultraviolet type mutations in xeroderma pigmentosum melanomas.Different molecular patterns in glioblastoma multiforme subtypes upon recurrencePhosphoinositide phosphatases in cell biology and disease.Regulation of the pentose phosphate pathway in cancerNovel V600E BRAF mutations in imatinib-naive and imatinib-resistant gastrointestinal stromal tumors.Characterization of a novel PTEN mutation in MDA-MB-453 breast carcinoma cell lineA detailed transcriptional map of the chromosome 12p12 tumour suppressor locus.Important role of indels in somatic mutations of human cancer genes.Molecular apocrine differentiation is a common feature of breast cancer in patients with germline PTEN mutations.R-RAS2 overexpression in tumors of the human central nervous system.Elevation of methylated DNA in KILLIN/PTEN in the plasma of patients with thyroid and/or breast cancerConditional deletion of the Pten gene in the mouse prostate induces prostatic intraepithelial neoplasms at early ages but a slow progression to prostate tumors.FISH analysis of PTEN in endometrial carcinoma. Comparison with SNP arrays and MLPA.The mTOR signaling pathway as a treatment target for intracranial neoplasmsPTEN hamartoma tumor syndrome: an overview.Crosstalking between androgen and PI3K/AKT signaling pathways in prostate cancer cells.PTEN increases autophagy and inhibits the ubiquitin-proteasome pathway in glioma cells independently of its lipid phosphatase activityPTEN: Multiple Functions in Human Malignant TumorsMiR-106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer.Differential Requirement for Pten Lipid and Protein Phosphatase Activity during Zebrafish Embryonic Development.PTEN gene expression and mutations in the PIK3CA gene as predictors of clinical benefit to anti-epidermal growth factor receptor antibody therapy in patients with KRAS wild-type metastatic colorectal cancer.Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
name
Mutations of the human PTEN gene.
@ast
Mutations of the human PTEN gene.
@en
type
label
Mutations of the human PTEN gene.
@ast
Mutations of the human PTEN gene.
@en
prefLabel
Mutations of the human PTEN gene.
@ast
Mutations of the human PTEN gene.
@en
P2860
P1433
P1476
Mutations of the human PTEN gene.
@en
P2093
P2860
P304
P356
10.1002/1098-1004(200008)16:2<109::AID-HUMU3>3.0.CO;2-0
P577
2000-01-01T00:00:00Z