Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer
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Enhancer malfunction in cancerHistone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and preventionFrequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkersEstablishment and characterization of a highly tumourigenic and cancer stem cell enriched pancreatic cancer cell line as a well defined model systemThe mutational landscape of chromatin regulatory factors across 4,623 tumor samples.A global profile of gene promoter methylation in treatment-naïve urothelial cancerWRAD: enabler of the SET1-family of H3K4 methyltransferases.KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation.Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer.Alteration of histone H3K4 methylation in glomerular podocytes associated with proteinuria in patients with membranous nephropathy.Evaluation of magnifying colonoscopy in the diagnosis of serrated polyps.The miR-200 family is increased in dysplastic lesions in ulcerative colitis patients.Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathwaysHistone methylase MLL1 has critical roles in tumor growth and angiogenesis and its knockdown suppresses tumor growth in vivo.Histone methyltransferase MLL3 contributes to genome-scale circadian transcription.Mutation of epigenetic regulators TET2 and MLL3 in patients with HTLV-I-induced acute adult T-cell leukemia.Interaction between MLL3 genetic polymorphisms, smoking, and alcohol drinking in laryngeal cancer: a case-control studyThe MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.Exome sequencing identifies frequent mutation of MLL2 in non-small cell lung carcinoma from Chinese patients.The good, the bad and the ugly: epigenetic mechanisms in glioblastoma.Examining the impact of gene variants on histone lysine methylationDriver mutations of cancer epigenomes.Pancreatic intraductal tubulopapillary neoplasm is genetically distinct from intraductal papillary mucinous neoplasm and ductal adenocarcinoma.Enhancer deregulation in cancer and other diseases.DNA methylation at hepatitis B viral integrants is associated with methylation at flanking human genomic sequences.Downregulation of MLL3 in esophageal squamous cell carcinoma is required for the growth and metastasis of cancer cells.Targeting histone methylation for colorectal cancerCase-control study of candidate gene methylation and adenomatous polyp formation.Regulation of tumour related genes by dynamic epigenetic alteration at enhancer regions in gastric epithelial cells infected by Epstein-Barr virus.Colorectal cancer risk and patients' survival: influence of polymorphisms in genes somatically mutated in colorectal tumors.Aberrant chromatin remodeling in gynecological cancer.Identification of different mutational profiles in cancers arising in specific colon segments by next generation sequencing.Hijacking a key chromatin modulator creates epigenetic vulnerability for MYC-driven cancer
P2860
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P2860
Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Frequent alteration of MLL3 fr ...... te deficient colorectal cancer
@ast
Frequent alteration of MLL3 fr ...... te deficient colorectal cancer
@en
type
label
Frequent alteration of MLL3 fr ...... te deficient colorectal cancer
@ast
Frequent alteration of MLL3 fr ...... te deficient colorectal cancer
@en
prefLabel
Frequent alteration of MLL3 fr ...... te deficient colorectal cancer
@ast
Frequent alteration of MLL3 fr ...... te deficient colorectal cancer
@en
P2093
P2860
P50
P1433
P1476
Frequent alteration of MLL3 fr ...... te deficient colorectal cancer
@en
P2093
Brittany North
Fumio Itoh
Hyun Soo Kim
Jaroslav Jelinek
Lanlan Shen
Mee-Yon Cho
Minoru Toyota
Ritsuko Oikawa
Saira S Ahmed
Tetsuya Hiraishi
P2860
P304
P356
10.1371/JOURNAL.PONE.0023320
P407
P577
2011-08-11T00:00:00Z