MLL3, a new human member of the TRX/MLL gene family, maps to 7q36, a chromosome region frequently deleted in myeloid leukaemia.
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Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.Targeted Disruption of the Interaction Between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase ComplexesColorectal Cancer Genetic Heterogeneity Delineated by Multi-Region SequencingThe mutational landscape of chromatin regulatory factors across 4,623 tumor samples.Gene expression analysis in response to lung toxicants: I. Sequencing and microarray development.Excess congenital non-synonymous variation in leukemia-associated genes in MLL- infant leukemia: a Children's Oncology Group report.Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies.Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancerMolecular mechanisms of pituitary organogenesis: In search of novel regulatory genes.Photoperiod influences growth and mll (mixed-lineage leukaemia) expression in Atlantic cod.Rbm15-Mkl1 interacts with the Setd1b histone H3-Lys4 methyltransferase via a SPOC domain that is required for cytokine-independent proliferation.Molecular pathways in pancreatic carcinogenesisA tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer.An Lnc RNA (GAS5)/SnoRNA-derived piRNA induces activation of TRAIL gene by site-specifically recruiting MLL/COMPASS-like complexes.MLL 5 protein forms intranuclear foci, and overexpression inhibits cell cycle progressionDisrupted intricacy of histone H3K4 methylation in neurodevelopmental disorders.Histone recognition and nuclear receptor co-activator functions of Drosophila cara mitad, a homolog of the N-terminal portion of mammalian MLL2 and MLL3Loss of Mll3 Catalytic Function Promotes Aberrant MyelopoiesisProfiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse.A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.Transcription factor Ap2delta associates with Ash2l and ALR, a trithorax family histone methyltransferase, to activate Hoxc8 transcriptionInteraction between MLL3 genetic polymorphisms, smoking, and alcohol drinking in laryngeal cancer: a case-control studyCancer genetics of epigenetic genes.Molecular signature of pancreatic adenocarcinoma: an insight from genotype to phenotype and challenges for targeted therapy.Isolation and bioinformatics analysis of differentially methylated genomic fragments in human gastric cancer.Histone H3 lysine 4 (H3K4) methylation in development and differentiationBinding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein.Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis.-7/7q- syndrome in myeloid-lineage hematopoietic malignancies: attempts to understand this complex disease entity.Synthesis, Optimization, and Evaluation of Novel Small Molecules as Antagonists of WDR5-MLL Interaction.MLL3/MLL4/COMPASS Family on Epigenetic Regulation of Enhancer Function and Cancer.SET/MLL family proteins in hematopoiesis and leukemia.Identification of frequently mutated genes with relevance to nonsense mediated mRNA decay in the high microsatellite instability cancers.Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors.Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1-WDR5 interaction.Development and validation of a targeted next generation DNA sequencing panel outperforming whole exome sequencing for the identification of clinically relevant genetic variants.Clinical impact of KMT2C and SPRY4 expression levels in intensively treated younger adult acute myeloid leukemia patients.Absence of MLL3 mutations in colorectal carcinomas of Korean patients.Somatic Mutations of the Mixed-Lineage Leukemia 3 (MLL3) Gene in Primary Breast Cancers
P2860
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P2860
MLL3, a new human member of the TRX/MLL gene family, maps to 7q36, a chromosome region frequently deleted in myeloid leukaemia.
description
2002 nî lūn-bûn
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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2002 թվականի փետրվարին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
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2002年论文
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name
MLL3, a new human member of th ...... deleted in myeloid leukaemia.
@ast
MLL3, a new human member of th ...... deleted in myeloid leukaemia.
@en
MLL3, a new human member of th ...... deleted in myeloid leukaemia.
@nl
type
label
MLL3, a new human member of th ...... deleted in myeloid leukaemia.
@ast
MLL3, a new human member of th ...... deleted in myeloid leukaemia.
@en
MLL3, a new human member of th ...... deleted in myeloid leukaemia.
@nl
prefLabel
MLL3, a new human member of th ...... deleted in myeloid leukaemia.
@ast
MLL3, a new human member of th ...... deleted in myeloid leukaemia.
@en
MLL3, a new human member of th ...... deleted in myeloid leukaemia.
@nl
P2093
P1433
P1476
MLL3, a new human member of th ...... y deleted in myeloid leukaemia
@en
P2093
Gérard Roizès
Marie Elisabeth Brun
Myriam Ruault
P356
10.1016/S0378-1119(02)00392-X
P407
P577
2002-02-01T00:00:00Z