Conformational Abs recognizing a generic amyloid fibril epitope.
about
Pauling and Corey's alpha-pleated sheet structure may define the prefibrillar amyloidogenic intermediate in amyloid diseaseExpression of Fap amyloids in Pseudomonas aeruginosa, P. fluorescens, and P. putida results in aggregation and increased biofilm formationMicrobial amyloids--functions and interactions within the hostAlzheimer's therapeutics: translation of preclinical science to clinical drug developmentFibrillogenesis of huntingtin and other glutamine containing proteinsA window into the heterogeneity of human cerebrospinal fluid Aβ peptidesMolecular basis for passive immunotherapy of Alzheimer's diseaseMolecular basis of -amyloid oligomer recognition with a conformational antibody fragmentStructural basis for the recognition and cross-linking of amyloid fibrils by human apolipoprotein EInduction of AApoAII amyloidosis by various heterogeneous amyloid fibrilsDistinct α-synuclein strains differentially promote tau inclusions in neuronsPhage display and peptide mapping of an immunoglobulin light chain fibril-related conformational epitopeAggregate-depleted brain fails to induce Aβ deposition in a mouse model of Alzheimer's diseaseAmyloid domains in the cell nucleus controlled by nucleoskeletal protein lamin B1 reveal a new pathway of mercury neurotoxicityAmyloid-β peptide-specific DARPins as a novel class of potential therapeutics for Alzheimer diseaseExtracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouseAnnular protofibrils are a structurally and functionally distinct type of amyloid oligomer.Oligomer-targeting with a conformational antibody fragment promotes toxicity in Aβ-expressing flies.Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen.Identification of fibrillogenic regions in human triosephosphate isomerase.Kinetic study of beta-amyloid residue accessibility using reductive alkylation and mass spectrometry.Structural classification of toxic amyloid oligomersMonoclonal antibodies recognize distinct conformational epitopes formed by polyglutamine in a mutant huntingtin fragment.Structural properties of Abeta protofibrils stabilized by a small molecule.RNA aptamers generated against oligomeric Abeta40 recognize common amyloid aptatopes with low specificity but high sensitivityA synergistic small-molecule combination directly eradicates diverse prion strain structuresDirected selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils.Amyloid-like adhesins produced by floc-forming and filamentous bacteria in activated sludgeConformational targeting of fibrillar polyglutamine proteins in live cells escalates aggregation and cytotoxicity.Inherent anti-amyloidogenic activity of human immunoglobulin gamma heavy chainsPhysiological IgM class catalytic antibodies selective for transthyretin amyloid.Soluble and mature amyloid fibrils in drusen depositsMolecular polymorphism of Abeta in Alzheimer's disease.α-synuclein reactive antibodies as diagnostic biomarkers in blood sera of Parkinson's disease patients.Orthogonal cross-seeding: an approach to explore protein aggregates in living cells.Immunoprecipitation of amyloid fibrils by the use of an antibody that recognizes a generic epitope common to amyloid fibrils.Characterization of the response of primary cells relevant to dialysis-related amyloidosis to β2-microglobulin monomer and fibrils.Vascular and metabolic dysfunction in Alzheimer's disease: a review.Amyloid beta-protein dimers rapidly form stable synaptotoxic protofibrils.Mutational analysis of the structural organization of polyglutamine aggregates.
P2860
Q24564070-07E0917A-EE25-4329-BC2D-AEDB15069719Q24611380-6236738C-C008-4E0E-BA01-D5B1CF084A5FQ26827214-358C3B14-ECD2-465B-A027-D1D0F519E548Q26829267-E7920FB8-057E-41E2-B8E2-CD9D758D4339Q26850062-D4ECC6A5-8463-43D2-AFB4-9889C8349347Q27010785-CB2FB052-B333-4276-905E-15892A00BA03Q27648521-1C9CA076-689D-4864-A757-73B813B500C2Q27670832-13638E1E-83C0-4FDA-AA1B-CD6D04B6A2F6Q28252183-C57F6A06-5023-4F61-9740-C3CDE7EAC0BAQ28254598-CDD4383D-227A-45D9-A1C0-612AF2B61774Q28293967-85227FD0-BE03-4D36-ACA6-3B860005B06DQ28388530-6B5D916E-FF13-4ACE-87D6-12FFC7142BD6Q28539753-23B5539F-D8FE-4C78-BC63-36A96EE31D15Q28649959-090A3358-5C90-48AD-BE02-341829230883Q28655482-FB4E22A8-770C-4DB5-A4B5-D263E3CCB966Q28741744-226FB630-AE93-4ED5-BFEC-2F40CD0D0427Q30157440-BE874C24-F09E-4E6A-9CD5-2B00E4FEB82BQ30317471-54318B37-993F-4B90-A712-42B36097850CQ30360888-CFAC243A-70DE-403F-BB55-CCA8C17672B1Q30384397-D59DFF6F-62C9-4F26-B1D3-20B41B8DF6FBQ30434894-36AF0A58-8A68-4756-A356-52ECEA62547EQ30484255-FAC421E1-F33E-4990-9754-40FB33DAF83CQ30490726-9BD190CE-5CFB-4748-A233-96433C7E8E0CQ30852039-39580776-F334-4EBD-979D-32438340D98BQ30879431-A68E7D4D-7039-4BD5-A3DA-2B30C9D23E39Q30885765-E50C6A9A-C8EF-4ED1-88B7-98E323BB2B17Q33307478-86319169-588F-4BC2-95E2-0C2F412E28B7Q33314528-575FE0A0-6655-4556-BBD7-E2B9576E50F5Q33459255-2B904FD6-4DD3-4EE6-82CD-AC72CA8E8EA1Q33569608-E68AE320-A41D-48A9-BAF1-E9A08DEBC3BBQ33676625-480B80D5-C138-4DD7-9D49-F4786CC38FA4Q33735695-1689CA71-4733-41F5-8BE7-EC46841BEFA8Q33741493-DA7541F2-7317-4836-A1A9-DCF4F16ADDBFQ33889446-EC97A42C-DB8D-4AA3-BA8E-EA97553EDD2EQ33958095-3E854FC5-213A-43A4-9EA8-F9F6559AF5E7Q34075450-00D5678B-4219-4E52-AD51-4A8E52E3CD23Q34077850-F31CECC0-84CD-4766-9224-320C512885BAQ34193337-C0E3D621-B75B-4F8B-B4B1-48B5455A5CB4Q34330681-37ED85B1-0D6E-46D8-9329-D48E0E6969CCQ34430560-B17B57EF-2904-4C19-AB30-C0A25B63CA8C
P2860
Conformational Abs recognizing a generic amyloid fibril epitope.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Conformational Abs recognizing a generic amyloid fibril epitope.
@ast
Conformational Abs recognizing a generic amyloid fibril epitope.
@en
Conformational Abs recognizing a generic amyloid fibril epitope.
@nl
type
label
Conformational Abs recognizing a generic amyloid fibril epitope.
@ast
Conformational Abs recognizing a generic amyloid fibril epitope.
@en
Conformational Abs recognizing a generic amyloid fibril epitope.
@nl
prefLabel
Conformational Abs recognizing a generic amyloid fibril epitope.
@ast
Conformational Abs recognizing a generic amyloid fibril epitope.
@en
Conformational Abs recognizing a generic amyloid fibril epitope.
@nl
P2860
P356
P1476
Conformational Abs recognizing a generic amyloid fibril epitope.
@en
P2093
Brian O'Nuallain
Ronald Wetzel
P2860
P304
P356
10.1073/PNAS.022662599
P407
P577
2002-01-29T00:00:00Z