Adeno-associated virus effectively mediates conditional gene modification in the brain
about
Francis Crick's legacy for neuroscience: between the alpha and the OmegaEfficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectorsObesity genetics in mouse and human: back and forth, and back againGene delivery strategies to promote spinal cord repairImpaired axonal transport in motor neurons correlates with clinical prion diseaseExosome-associated AAV vector as a robust and convenient neuroscience toolNMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrusSonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivoConditional, genetic disruption of ciliary neurotrophic factor receptors reveals a role in adult motor neuron survivalActivation of the neuronal extracellular signal-regulated kinase 2 in the spinal cord dorsal horn is required for complete Freund's adjuvant-induced pain hypersensitivityN-Methyl-D-aspartate receptor (NMDAR) independent maintenance of inflammatory pain.Silencing [Formula: see text] Rescues Tau Pathologies and Memory Deficits through Rescuing PP2A and Inhibiting GSK-3β Signaling in Human Tau Transgenic Mice.Rapid Molecular Profiling of Defined Cell Types Using Viral TRAPPitx2 deletion in pituitary gonadotropes is compatible with gonadal development, puberty, and fertilityHDAC3 is a critical negative regulator of long-term memory formation.Coordinate lentiviral expression of Cre recombinase and RFP/EGFP mediated by FMDV 2A and analysis of Cre activity.A vector-host system to fingerprint virus tropismY1 and Y5 receptors are both required for the regulation of food intake and energy homeostasis in miceTransneuronal tracing of diverse CNS circuits by Cre-mediated induction of wheat germ agglutinin in transgenic mice.The central and basolateral amygdala are critical sites of neuropeptide Y/Y2 receptor-mediated regulation of anxiety and depression.Therapeutic developments in the treatment of amyotrophic lateral sclerosis.Hippocampal focal knockout of CBP affects specific histone modifications, long-term potentiation, and long-term memory.Ablation of Fmrp in adult neural stem cells disrupts hippocampus-dependent learningDistinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo.Enhanced selective gene delivery to neural stem cells in vivo by an adeno-associated viral variantVGF and Its C-Terminal Peptide TLQP-62 Regulate Memory Formation in Hippocampus via a BDNF-TrkB-Dependent Mechanism.Suppression of endogenous PPARγ increases vulnerability to methamphetamine-induced injury in mouse nigrostriatal dopaminergic pathway.Aberrant Purkinje cell activity is the cause of dystonia in a shRNA-based mouse model of Rapid Onset Dystonia-Parkinsonism.IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes.Differential effects of brain-derived neurotrophic factor and neurotrophin-3 on hindlimb function in paraplegic rats.Controlled and localized genetic manipulation in the brain.Generation of brain tumours in mice by Cre-mediated recombination of neural progenitors in situ with the tamoxifen metabolite endoxifen.Targeted axonal import (TAxI) peptide delivers functional proteins into spinal cord motor neurons after peripheral administration.A genetic approach to dissect sexually dimorphic behaviors.Optimized adeno-associated virus 8 produces hepatocyte-specific Cre-mediated recombination without toxicity or affecting liver regeneration.Long-term reversal of cholinergic neuronal decline in aged non-human primates by lentiviral NGF gene deliveryIncreased hippocampal neurogenesis and accelerated response to antidepressants in mice with specific deletion of CREB in the hippocampus: role of cAMP response-element modulator τ.Evaluation of cre recombinase delivery in mammalian cells using baculovirus infection.Ultramicroscopy reveals axonal transport impairments in cortical motor neurons at prion diseaseCardiac-specific inducible and conditional gene targeting in mice.
P2860
Q21146391-87254723-2D69-4A43-B0C5-735F8835EBD1Q24797018-86FBEDE8-2977-46CC-B855-C54B5F57C263Q26782027-522595BB-F662-434B-89F7-FC12F0990C0CQ26825131-F7686100-D4D3-4150-A369-9800CEAD63A6Q27316376-E9131435-7912-419C-BE12-09DB9C7F0104Q27323458-72BA322F-D52B-4EC1-83F0-B765B4579E24Q28505756-CEEC0A3E-C15D-43E4-A393-C61A2A647DFCQ28572747-55B9E142-78D2-4262-B06B-386F99BA3B8CQ28591327-E7781BB3-8F9D-4437-9E07-157D1DDA7108Q30439378-8C8E3B26-9057-4560-A25D-31531DABA57DQ33701859-0DA66B27-8ACC-40ED-A9E3-19A57E640866Q33766526-BB94E77C-3D80-46C6-B31B-B6F3B8330CC4Q33811678-5A2B5F29-6F74-45CF-B497-5DC3145F0B3FQ34072553-01E0CD6D-43FD-4AEC-828C-5941B3817DEEQ34158695-3D11B235-50BB-4166-A24F-6AE1229F70EFQ34244585-37D55055-80F1-4623-B8E1-D3E0081510D0Q34290417-65379B3C-16E5-4608-939D-9E3EFA7B220EQ34328760-2A1421F8-BB7B-4D15-B5AA-B5E4F86D9E6FQ34381586-EFC46E8E-FCEC-415A-85C2-F3A3351A9961Q34775163-7C68615C-0BAA-4CDA-B2F6-764B9346F75BQ34974850-2536C6A5-D17A-4BEC-A6BB-A2E5D0FC0A45Q35112173-EE86AB7C-4308-4175-A1DB-1846E7DAB1CDQ35120052-7D145F52-1526-4FB9-B9A9-D4ACE7B34F72Q35247785-E45A17A1-C605-46D5-9239-DCE72EA9BE43Q35635046-8C39E6BA-2FBE-48F1-9D6D-85443BCE67FBQ35851548-19F476A9-61F1-418F-A507-14B2E8DD38BFQ35957491-92B960C4-2371-495D-81EF-D1543DF7AA61Q36269315-08751C42-BF57-4A87-ADC7-9CD44F92DB2FQ36321767-7C96EE61-5EE6-42BA-AB03-31E31CDF7256Q36431214-A966CB09-A324-4629-8C09-2747475CD22CQ36517060-1CE4217D-C166-42A9-84DF-F30036EB3F3EQ36627734-277E661F-7BF9-4EF6-9ED3-A2B399A0413FQ36658903-75B36CAA-ED6B-4DB3-8B59-5A5AD2C195C4Q36765999-ADD81A6D-57F9-4060-AA9A-88DE80698924Q36846505-3B124F5D-9F19-4A04-AFD7-F37FA4611646Q37076735-238670FB-DC3B-4CBD-BE65-8AB735C95C0CQ37128122-E2651BFD-205C-46AC-B31F-5573E66CDD87Q37136427-AF283EF3-CC7B-4DF3-B9C6-C406915A009EQ37282187-5C7C35EF-E0F7-4C21-9A76-BFD0D2CC867FQ37373830-CD1079B5-2C2A-4C33-9AC6-BC1F1B964282
P2860
Adeno-associated virus effectively mediates conditional gene modification in the brain
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Adeno-associated virus effectively mediates conditional gene modification in the brain
@ast
Adeno-associated virus effectively mediates conditional gene modification in the brain
@en
Adeno-associated virus effectively mediates conditional gene modification in the brain
@nl
type
label
Adeno-associated virus effectively mediates conditional gene modification in the brain
@ast
Adeno-associated virus effectively mediates conditional gene modification in the brain
@en
Adeno-associated virus effectively mediates conditional gene modification in the brain
@nl
prefLabel
Adeno-associated virus effectively mediates conditional gene modification in the brain
@ast
Adeno-associated virus effectively mediates conditional gene modification in the brain
@en
Adeno-associated virus effectively mediates conditional gene modification in the brain
@nl
P2093
P2860
P356
P1476
Adeno-associated virus effectively mediates conditional gene modification in the brain
@en
P2093
Brian K Kaspar
Bryce Vissel
David Schaffer
Eugene P Brandon
Fred H Gage
Inder M Verma
Kuo-Fen Lee
Lynne Randolph-Moore
Rolf Muller
Stephen F Heinemann
P2860
P304
P356
10.1073/PNAS.042678699
P407
P577
2002-02-12T00:00:00Z