Inhibition of retrograde transport protects mice from lethal ricin challenge.
about
Antibody to ricin a chain hinders intracellular routing of toxin and protects cells even after toxin has been internalizedOptimized 5-Membered Heterocycle-Linked Pterins for the Inhibition of Ricin Toxin AStability of isolated antibody-antigen complexes as a predictive tool for selecting toxin neutralizing antibodiesApproaches to treatment of emerging Shiga toxin-producing Escherichia coli infections highlighting the O104:H4 serotypeSmall-molecule inhibitor leads of ribosome-inactivating proteins developed using the doorstop approachA therapeutic chemical chaperone inhibits cholera intoxication and unfolding/translocation of the cholera toxin A1 subunitIdentification of small molecules that suppress ricin-induced stress-activated signaling pathwaysExploring anti-bacterial compounds against intracellular LegionellaBaicalin inhibits the lethality of ricin in mice by inducing protein oligomerization.Recent progress of Shiga toxin neutralizer for treatment of infections by Shiga toxin-producing Escherichia coli.The enemy within us: lessons from the 2011 European Escherichia coli O104:H4 outbreakRetrograde Trafficking Inhibitor of Shiga Toxins Reduces Morbidity and Mortality of Mice Infected with Enterohemorrhagic Escherichia coli(S)-N-Methyldihydroquinazolinones are the Active Enantiomers of Retro-2 Derived Compounds against Toxins.Development of a quantitative RT-PCR assay to examine the kinetics of ribosome depurination by ribosome inactivating proteins using Saccharomyces cerevisiae as a model.Neutralising antibodies against ricin toxin.At the crossroads of chemistry and cell biology: inhibiting membrane traffic by small molecules.Identification of a peptide-based neutralizer that potently inhibits both Shiga toxins 1 and 2 by targeting specific receptor-binding regionsSyntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction.[Phenotypic screens or one stone to kill two birds: discover the target and its pharmacological regulator].Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses.JC polyomavirus attachment, entry, and trafficking: unlocking the keys to a fatal infection.Common pharmacophore of structurally distinct small-molecule inhibitors of intracellular retrograde trafficking of ribosome inactivating proteins.Dislocation of ricin toxin A chains in human cells utilizes selective cellular factorsNovel class of potential therapeutics that target ricin retrograde translocation.Physiology and pathology of endosome-to-Golgi retrograde sorting.Antisecretory factor peptide AF-16 inhibits the secreted autotransporter toxin-stimulated transcellular and paracellular passages of fluid in cultured human enterocyte-like cellsEndophilin-A2 functions in membrane scission in clathrin-independent endocytosis.High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides.Different types of cell death induced by enterotoxins.Structural optimization of a retrograde trafficking inhibitor that protects cells from infections by human polyoma- and papillomaviruses.Characterization and epitope mapping of the polyclonal antibody repertoire elicited by ricin holotoxin-based vaccinationPassive and active vaccination strategies to prevent ricin poisoning.Ricinus communis intoxications in human and veterinary medicine-a summary of real cases.Synthesis, Chiral Separation, Absolute Configuration Assignment, and Biological Activity of Enantiomers of Retro-1 as Potent Inhibitors of Shiga Toxin.The Proteome of the Isolated Chlamydia trachomatis Containing Vacuole Reveals a Complex Trafficking Platform Enriched for Retromer ComponentsThe need for continued development of ricin countermeasures.Rapid Detection of Ricin in Serum Based on Cu-Chelated Magnetic Beads Using Mass Spectrometry.Baicalin inhibits the lethality of Shiga-like toxin 2 in mice.Retro-1 Analogues Differentially Affect Oligonucleotide Delivery and Toxin Trafficking.Applications in Stimulated Emission Depletion Microscopy: Localization of a Protein Toxin in the Endoplasmic Reticulum Following Retrograde Transport.
P2860
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P2860
Inhibition of retrograde transport protects mice from lethal ricin challenge.
description
2010 nî lūn-bûn
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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
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2010年學術文章
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name
Inhibition of retrograde transport protects mice from lethal ricin challenge.
@ast
Inhibition of retrograde transport protects mice from lethal ricin challenge.
@en
Inhibition of retrograde transport protects mice from lethal ricin challenge.
@nl
type
label
Inhibition of retrograde transport protects mice from lethal ricin challenge.
@ast
Inhibition of retrograde transport protects mice from lethal ricin challenge.
@en
Inhibition of retrograde transport protects mice from lethal ricin challenge.
@nl
prefLabel
Inhibition of retrograde transport protects mice from lethal ricin challenge.
@ast
Inhibition of retrograde transport protects mice from lethal ricin challenge.
@en
Inhibition of retrograde transport protects mice from lethal ricin challenge.
@nl
P2093
P1433
P1476
Inhibition of retrograde transport protects mice from lethal ricin challenge.
@en
P2093
Bahne Stechmann
Bruno Beaumelle
Daniel Gillet
Didier Sauvaire
Emilie Gobbo
Goulven Merer
Graça Raposo
Julien Barbier
Laetitia Panigai
Ludger Johannes
P304
P356
10.1016/J.CELL.2010.01.043
P407
P577
2010-04-01T00:00:00Z