GSK3, a master switch regulating cell-fate specification and tumorigenesis.
about
Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activityIntegrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta.Post-transcriptional regulation of thioredoxin by the stress inducible heterogenous ribonucleoprotein A18.CREB DNA binding activity is inhibited by glycogen synthase kinase-3 beta and facilitated by lithiumA novel mass spectrometry-based assay for GSK-3beta activity.Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathwaysCellular plasticity cascades in the pathophysiology and treatment of bipolar disorderInhibition of glioblastoma growth by the thiadiazolidinone compound TDZD-8Evidence for a role of glycogen synthase kinase-3 beta in rodent spermatogenesisPhylogenetic diversification of glycogen synthase kinase 3/SHAGGY-like kinase genes in plantsExpression and characterization of GSK-3 mutants and their effect on beta-catenin phosphorylation in intact cells.Expression analysis of E-cadherin, Slug and GSK3beta in invasive ductal carcinoma of breast.Stabilization of mismatch repair gene PMS2 by glycogen synthase kinase 3beta is implicated in the treatment of cervical carcinomaBiological and clinical significance of GSK-3beta in mantle cell lymphoma--an immunohistochemical study.Functional significance for a heterogenous ribonucleoprotein A18 signature RNA motif in the 3'-untranslated region of ataxia telangiectasia mutated and Rad3-related (ATR) transcript.Identification of protein kinases dysregulated in CD4(+) T cells in pathogenic versus apathogenic simian immunodeficiency virus infection.Prediction of the binding mode between GSK3β and a peptide derived from GSKIP using molecular dynamics simulation.PI3K/mTOR inhibition markedly potentiates HDAC inhibitor activity in NHL cells through BIM- and MCL-1-dependent mechanisms in vitro and in vivo.A hierarchical phosphorylation cascade that regulates the timing of PERIOD nuclear entry reveals novel roles for proline-directed kinases and GSK-3beta/SGG in circadian clocks.Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis.ILKAP regulates ILK signaling and inhibits anchorage-independent growth.Beta-parvin inhibits integrin-linked kinase signaling and is downregulated in breast cancer.GSK3 takes centre stage more than 20 years after its discovery.Combinatorial cell-specific regulation of GSK3 directs cell differentiation and polarity in DictyosteliumPriming-dependent phosphorylation and regulation of the tumor suppressor pVHL by glycogen synthase kinase 3.Involvement of GSK-3beta and DYRK1B in differentiation-inducing factor-3-induced phosphorylation of cyclin D1 in HeLa cells.Phosphorylation of the cytoskeletal protein CAP1 controls its association with cofilin and actin.Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation.GSK-3 modulates cellular responses to a broad spectrum of kinase inhibitorsDevelopmental downregulation of Xenopus cyclin E is phosphorylation and nuclear import dependent and is mediated by ubiquitination.Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions.A Dihydroxy-pentamethoxyflavone from Gardenia obtusifolia suppresses proliferation and promotes apoptosis of tumor cells through modulation of multiple cell signaling pathways.SET oncoprotein overexpression in B-cell chronic lymphocytic leukemia and non-Hodgkin lymphoma: a predictor of aggressive disease and a new treatment target.Differential expression of GSK3β and pS9GSK3β in normal human tissues: can pS9GSK3β be an epithelial marker?Insights into morphogenesis from a simple developmental system.Altered regulation of tau phosphorylation in a mouse model of down syndrome agingFormin mDia1 mediates vascular remodeling via integration of oxidative and signal transduction pathways.Inhibition of glycogen synthase kinase-3beta improves tolerance to ischemia in hypertrophied hearts.Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.Role of PI3K-AKT-mTOR and Wnt Signaling Pathways in Transition of G1-S Phase of Cell Cycle in Cancer Cells.
P2860
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P2860
GSK3, a master switch regulating cell-fate specification and tumorigenesis.
description
2000 nî lūn-bûn
@nan
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
GSK3, a master switch regulating cell-fate specification and tumorigenesis.
@ast
GSK3, a master switch regulating cell-fate specification and tumorigenesis.
@en
GSK3, a master switch regulating cell-fate specification and tumorigenesis.
@nl
type
label
GSK3, a master switch regulating cell-fate specification and tumorigenesis.
@ast
GSK3, a master switch regulating cell-fate specification and tumorigenesis.
@en
GSK3, a master switch regulating cell-fate specification and tumorigenesis.
@nl
prefLabel
GSK3, a master switch regulating cell-fate specification and tumorigenesis.
@ast
GSK3, a master switch regulating cell-fate specification and tumorigenesis.
@en
GSK3, a master switch regulating cell-fate specification and tumorigenesis.
@nl
P1476
GSK3, a master switch regulating cell-fate specification and tumorigenesis.
@en
P304
P356
10.1016/S0959-437X(00)00120-9
P577
2000-10-01T00:00:00Z