Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle. - Wikidata - awgldk - TriplyDB

Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle.

Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle.

http://www.wikidata.org/entity/Q34028528

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Adeno-associated Virus as a Mammalian DNA Vector Gene therapy for cardiovascular disease: advances in vector development, targeting, and delivery for clinical translation Adeno-associated virus at 50: a golden anniversary of discovery, research, and gene therapy success--a personal perspective Gene delivery to adipose tissue using transcriptionally targeted rAAV8 vectors Cardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failure The structure of adeno-associated virus serotype 3B (AAV-3B): Insights into receptor binding and immune evasion Electron microscopy analysis of a disaccharide analog complex reveals receptor interactions of adeno-associated virus Cardiac-targeted delivery of regulatory RNA molecules and genes for the treatment of heart failure E Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal--Tailored Acceleration of AAV Evolution Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X A magnetic nanoparticle-based multiple-gene delivery system for transfection of porcine kidney cells.Quantitative 3D tracing of gene-delivery viral vectors in human cells and animal tissues.Reengineered AAV vectors: old dog, new tricks.AAV's anatomy: roadmap for optimizing vectors for translational success Engineering liver-detargeted AAV9 vectors for cardiac and musculoskeletal gene transfer.Efficient transduction and optogenetic stimulation of retinal bipolar cells by a synthetic adeno-associated virus capsid and promoter.Adeno-associated virus: a key to the human genome?Synthetic virology: engineering viruses for gene delivery Recombinant adeno-associated virus utilizes cell-specific infectious entry mechanisms Phase 1 gene therapy for Duchenne muscular dystrophy using a translational optimized AAV vector.A potential role of distinctively delayed blood clearance of recombinant adeno-associated virus serotype 9 in robust cardiac transduction.Preclinical differences of intravascular AAV9 delivery to neurons and glia: a comparative study of adult mice and nonhuman primates AAV-6 mediated efficient transduction of mouse lower airways Systemic RNAi delivery to the muscles of ROSA26 mice reduces lacZ expression Improving clinical efficacy of adeno associated vectors by rational capsid bioengineering.Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing α1-antitrypsin: interim results.Systemic gene transfer to skeletal muscle using reengineered AAV vectors Identification of the heparin binding site on adeno-associated virus serotype 3B (AAV-3B).Controlling AAV Tropism in the Nervous System with Natural and Engineered Capsids.The AAV vector toolkit: poised at the clinical crossroads An siRNA Screen Identifies the U2 snRNP Spliceosome as a Host Restriction Factor for Recombinant Adeno-associated Viruses Identification and Validation of Small Molecules That Enhance Recombinant Adeno-associated Virus Transduction following High-Throughput Screens.Human galectin 3 binding protein interacts with recombinant adeno-associated virus type 6 The threefold protrusions of adeno-associated virus type 8 are involved in cell surface targeting as well as postattachment processing.Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles.Mapping a neutralizing epitope onto the capsid of adeno-associated virus serotype 8.Glycan binding avidity determines the systemic fate of adeno-associated virus type 9.Perspective on Adeno-Associated Virus Capsid Modification for Duchenne Muscular Dystrophy Gene Therapy Hepatocyte Heparan Sulfate Is Required for Adeno-Associated Virus 2 but Dispensable for Adenovirus 5 Liver Transduction In Vivo.Creation of a cardiotropic adeno-associated virus: the story of viral directed evolution.

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Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle.

http://www.wikidata.org/entity/Q34028528

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Reengineering a receptor footp ...... temic gene transfer to muscle.

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Reengineering a receptor footp ...... temic gene transfer to muscle.

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Reengineering a receptor footp ...... temic gene transfer to muscle.

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Reengineering a receptor footp ...... temic gene transfer to muscle.

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Reengineering a receptor footp ...... temic gene transfer to muscle.

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Reengineering a receptor footp ...... temic gene transfer to muscle.

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Reengineering a receptor footp ...... temic gene transfer to muscle.

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Reengineering a receptor footp ...... temic gene transfer to muscle.

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Nature Biotechnology

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Reengineering a receptor footp ...... temic gene transfer to muscle.

@en

P2093

Aravind Asokan

http://www.w3.org/2001/XMLSchema#string

Chengwen Li

http://www.w3.org/2001/XMLSchema#string

Hyun-Joo Nam

http://www.w3.org/2001/XMLSchema#string

Jana L Phillips

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Jon Wolff

http://www.w3.org/2001/XMLSchema#string

Julia C Conway

http://www.w3.org/2001/XMLSchema#string

Julia Hegge

http://www.w3.org/2001/XMLSchema#string

Nina DiPrimio

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R Jude Samulski

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Rebecca Sinnott

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P2860

The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy.

Hemagglutinin receptor binding avidity drives influenza A virus antigenic drift

Structure of Adeno-Associated Virus Serotype 8, a Gene Therapy Vector

A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection.

Systemic delivery of genes to striated muscles using adeno-associated viral vectors.

Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection.

Sequencing and analyses of all known human rhinovirus genomes reveal structure and evolution.

Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8.

Single amino acid changes can influence titer, heparin binding, and tissue tropism in different adeno-associated virus serotypes.

New recombinant serotypes of AAV vectors.

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79-82

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scholarly article

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10.1038/NBT.1599

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1

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28

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Mavis Agbandje-McKenna

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2009-12-27T00:00:00Z

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40786326

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1040351346

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20037580

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2912150

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