Single amino acid changes can influence titer, heparin binding, and tissue tropism in different adeno-associated virus serotypes. - Wikidata - awgldk - TriplyDB

Single amino acid changes can influence titer, heparin binding, and tissue tropism in different adeno-associated virus serotypes.

Single amino acid changes can influence titer, heparin binding, and tissue tropism in different adeno-associated virus serotypes.

http://www.wikidata.org/entity/Q35139648

about

Biology of adeno-associated viral vectors in the central nervous system A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells Progresses towards safe and efficient gene therapy vectors Adeno-associated Virus as a Mammalian DNA Vector Parvovirus glycan interactions Viral quasispecies evolution Structure of Adeno-Associated Virus Serotype 8, a Gene Therapy Vector Structural Characterization of the Dual Glycan Binding Adeno-Associated Virus Serotype 6 Structures of Merkel Cell Polyomavirus VP1 Complexes Define a Sialic Acid Binding Site Required for Infection Structural Studies of Adeno-Associated Virus Serotype 8 Capsid Transitions Associated with Endosomal Trafficking Structure–function analysis of receptor-binding in adeno-associated virus serotype 6 (AAV-6)Structural Insights into Adeno-Associated Virus Serotype 5 Electron microscopy analysis of a disaccharide analog complex reveals receptor interactions of adeno-associated virus Recombinant adeno-associated viral (rAAV) vectors mediate efficient gene transduction in cultured neonatal and adult microglia Structure of neurotropic adeno-associated virus AAVrh.8.Comparative analysis of adeno-associated virus capsid stability and dynamics In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses.A single amino acid substitution in the murine norovirus capsid protein is sufficient for attenuation in vivo.Molecular engineering of viral gene delivery vehicles DNA shuffling of adeno-associated virus yields functionally diverse viral progeny Directed evolution of a novel adeno-associated virus (AAV) vector that crosses the seizure-compromised blood-brain barrier (BBB).Sites in the AAV5 capsid tolerant to deletions and tandem duplications.Scalable downstream strategies for purification of recombinant adeno- associated virus vectors in light of the properties.Transduction efficiencies of novel AAV vectors in mouse airway epithelium in vivo and human ciliated airway epithelium in vitro.Immune responses to AAV in canine muscle monitored by cellular assays and noninvasive imaging.Engineering liver-detargeted AAV9 vectors for cardiac and musculoskeletal gene transfer.Glycosaminoglycans and sialylated glycans sequentially facilitate Merkel cell polyomavirus infectious entry.Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle.Intramuscular AAV delivery of NT-3 alters synaptic transmission to motoneurons in adult rats.Efficient transduction and optogenetic stimulation of retinal bipolar cells by a synthetic adeno-associated virus capsid and promoter.Novel adeno-associated viruses derived from pig tissues transduce most major organs in mice.Modeling Pulmonary Disease Pathways Using Recombinant Adeno-Associated Virus 6.2.Optimization of the capsid of recombinant adeno-associated virus 2 (AAV2) vectors: the final threshold?Expanded repertoire of AAV vector serotypes mediate unique patterns of transduction in mouse brain.Recombinant adeno-associated virus serotype 6 efficiently transduces primary human melanocytes Terminal N-linked galactose is the primary receptor for adeno-associated virus 9.Three amino acid mutations (F51L, T59A, and S390L) in the capsid protein of the hepatitis E virus collectively contribute to virus attenuation.Identification and mutagenesis of the adeno-associated virus 5 sialic acid binding region.Multiple roles for sialylated glycans in determining the cardiopulmonary tropism of adeno-associated virus 4 Preclinical differences of intravascular AAV9 delivery to neurons and glia: a comparative study of adult mice and nonhuman primates

P2860

Q21129328-A95E2654-71EF-432F-943B-AED6D9955DDA Q21142728-1FBE4654-F4BF-40AA-9B27-3444E17F9E1C Q26781432-B48E1891-8333-4320-99CB-1C8C1CF35A6F Q26782605-63D21199-3D1E-4B63-AE4F-C15DA5C8B760 Q26858992-4804E88D-31D0-4586-ABC4-F47AD87C63BC Q27013917-08FACEF4-453B-4F11-91AF-CA8A6AA3133C Q27647639-646DD14E-C3D8-435D-B78D-CEC4B0C579AB Q27664641-5FC0AD78-EB0E-44D7-AB81-6B4F3AB4927D Q27671637-FB3E4356-6008-4F7B-AD89-55A13C221852 Q27673394-C4AA2DD1-F4D8-44BE-ADC7-30CD1BC0095D Q27673885-DA05C3A1-F84F-4ADF-BA3D-7690F50BE8F8 Q27679454-F7FFC612-A37A-4873-8979-D38B05A90488 Q27679952-5800864A-1B36-4949-96CB-6B83C3A51FFF Q28386583-93D10421-8760-4A94-A6B5-CFA08CFBF780 Q30152836-858114D3-4EF1-4A2F-88BF-FBEE654C366A Q30557598-598175BE-D297-4829-9CC2-0692B69E9E19 Q33327474-26EFB4D5-1A5D-4208-9773-C7DB1ABDDF8C Q33336969-7264626C-DEDF-4EFB-8DD9-38E88939C809 Q33353795-888735E1-EC13-4906-BC42-B2980715064A Q33363531-1018AEC7-8B2D-46F7-B3AE-724EF8FC289B Q33521174-26AB2FA5-1F8C-4595-BEED-34D5E783B77E Q33526697-D115B746-3228-4056-AE1B-E23025051DE5 Q33555259-DA6B53CB-F6BB-460A-AF75-995D50B7777C Q33713277-015C6582-24D7-4AFF-82D6-5FF1B23B31E4 Q33731159-DE149963-EC9B-46E9-B329-11F30EA460F7 Q33833473-7115C85D-6C4A-4606-91CB-62ED98FFFC46 Q33987448-83D36A1F-BECD-450B-979A-FAF5BFA9A0EB Q34028528-EEB0ED65-D7EC-4EA9-ADF8-C8087E843679 Q34147451-04A64AD8-BC4D-4AD3-8D97-9A6340F95DE2 Q34342494-AB0DDC94-9E83-4467-8384-7A1BA2812831 Q34384998-6D562588-016D-4694-9574-87A9BDCEBE78 Q34470424-BD19216F-1409-4320-BA94-EB2A5005DD2E Q34634722-C611672B-365B-482B-8F9D-F5AC33FCC5E5 Q34664932-AD1FFA0B-6997-4001-A226-36FECC0E1CE8 Q34706818-F27624AC-EC1B-4DB3-A4AE-520BA849F447 Q34787342-D46C44B9-BAD7-4FEF-BCB4-FD0A996F9972 Q34982710-0C38A888-71FB-458C-ADBE-A4FAB0388F4D Q34991472-BEDFDE79-0F10-4394-A1F6-0AAB9E784289 Q34997974-90E1ECAA-D0C5-4CBC-BDC9-DCB7124F8611 Q35086714-0099C86E-44DE-4C61-97AF-5F908CDC8A34

P2860

Single amino acid changes can influence titer, heparin binding, and tissue tropism in different adeno-associated virus serotypes.

http://www.wikidata.org/entity/Q35139648

description

2006 nî lūn-bûn

@nan

2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Single amino acid changes can ...... no-associated virus serotypes.

@ast

Single amino acid changes can ...... no-associated virus serotypes.

@en

type

label

Single amino acid changes can ...... no-associated virus serotypes.

@ast

Single amino acid changes can ...... no-associated virus serotypes.

@en

prefLabel

Single amino acid changes can ...... no-associated virus serotypes.

@ast

Single amino acid changes can ...... no-associated virus serotypes.

@en

P1433

Q35139648-E5896E01-97CB-4FF9-93E6-25FB7731FE0C

P1476

Q35139648-A22139D2-2DE8-451E-98B5-8931706C01B1

P2093

Q35139648-1807516A-6F64-4E2E-820D-782EA635F4B0

Q35139648-507044AA-FCE0-41FE-9380-84223926DC74

Q35139648-79295C41-70B9-4943-9B05-2A485905C47E

Q35139648-A82CA3B7-ACEE-45C4-9F15-854189E08577

Q35139648-B28AA38E-8408-4158-9040-9F544913AEF8

P2860

Q35139648-04242996-7928-4601-8116-E922806F9FC9

Q35139648-1145B6F9-B1A0-430F-AE9C-A5375D5B8754

Q35139648-141E4941-E255-461A-AADB-2A49EFB6D600

Q35139648-22F99A1E-0D9F-4935-92EB-ED39F9449917

Q35139648-236F3C69-CACC-4A15-AF31-554C9E66F65B

Q35139648-29B2DC3E-114C-4D72-AAF3-B5D57FEF98A6

Q35139648-2DF615F5-BB80-4CB1-A2A2-93C53FB135BF

Q35139648-321A3D43-0CED-446F-A780-442B9D794C34

Q35139648-35F7F448-69A5-4D66-B4F0-19955D8832D2

Q35139648-45830C22-3CC8-4DD8-A2B6-6A2B9B59B1DB

P304

Q35139648-71348D44-A441-4F1B-8376-CD82CF7287DB

P31

Q35139648-E552CECE-9736-48B1-87D6-91BF0F373790

P356

Q35139648-E83D6A2F-2FF0-441D-AB48-835BCAA7D3B3

P407

Q35139648-B8E22D0B-75DF-427C-B33C-C6BAB2A2DA40

P433

Q35139648-786F56CC-D893-4DA7-860A-EC3025BD4944

P478

Q35139648-4796C154-7773-44AD-A388-8D85362570EE

P50

Q35139648-EEB0181A-E314-467F-9642-BBECB465C437

P577

Q35139648-8A663BC1-8079-4679-82D9-1FFF50904B49

P698

Q35139648-A60406AE-98BB-47AC-AA0C-E39CABCB13EE

P932

Q35139648-318B15AD-4E04-4252-BCD8-F988A5857AE5

P356

P1433

Journal of Virology

P1476

Single amino acid changes can ...... no-associated virus serotypes.

@en

P2093

Aravind Asokan

http://www.w3.org/2001/XMLSchema#string

Joshua C Grieger

http://www.w3.org/2001/XMLSchema#string

Lakshmanan Govindasamy

http://www.w3.org/2001/XMLSchema#string

R Jude Samulski

http://www.w3.org/2001/XMLSchema#string

Zhijian Wu

http://www.w3.org/2001/XMLSchema#string

P2860

Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism.

Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus

Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectors

Adeno-associated virus serotype 4 (AAV4) and AAV5 both require sialic acid binding for hemagglutination and efficient transduction but differ in sialic acid linkage specificity

Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions

The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy.

SWISS-MODEL: An automated protein homology-modeling server

Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.

Adeno-associated virus serotypes: vector toolkit for human gene therapy.

Structure of adeno-associated virus type 4.

P304

11393-11397

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/JVI.01288-06

http://www.w3.org/2001/XMLSchema#string

P407

P433

22

http://www.w3.org/2001/XMLSchema#string

P478

80

http://www.w3.org/2001/XMLSchema#string

P50

Mavis Agbandje-McKenna

P577

2006-08-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

16943302

http://www.w3.org/2001/XMLSchema#string

P932

1642158

http://www.w3.org/2001/XMLSchema#string