EZH2 couples pancreatic regeneration to neoplastic progression.
about
Reserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tractPancreatic Cancer, A Mis-interpreter of the Epigenetic LanguagePharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studiesEzh2 Acts as a Tumor Suppressor in Kras-driven Lung Adenocarcinoma.EZH2 is associated with malignant behavior in pancreatic IPMN via p27Kip1 downregulation.Regulation and Role of EZH2 in CancerPD2/Paf1 depletion in pancreatic acinar cells promotes acinar-to-ductal metaplasia.Small-molecular modulators of cancer-associated epigenetic mechanisms.Prognostic value of EZH2 expression and activity in renal cell carcinoma: a prospective study.Regeneration and repair of the exocrine pancreas.3-Deazaneplanocin A (DZNep), an inhibitor of the histone methyltransferase EZH2, induces apoptosis and reduces cell migration in chondrosarcoma cells.Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism.Bmi1 is required for regeneration of the exocrine pancreas in miceImpaired PRC2 activity promotes transcriptional instability and favors breast tumorigenesisTR4 Nuclear Receptor Alters the Prostate Cancer CD133+ Stem/Progenitor Cell Invasion via Modulating the EZH2-Related Metastasis Gene ExpressionEZH2 promotes cell migration and invasion but not alters cell proliferation by suppressing E-cadherin, partly through association with MALAT-1 in pancreatic cancer.HIFI-α activation underlies a functional switch in the paradoxical role of Ezh2/PRC2 in breast cancer.Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication.Senescence in pancreatic carcinogenesis: from signalling to chromatin remodelling and epigenetics.Epigenetic dysregulation in glioma.The controversial role of the Polycomb group proteins in transcription and cancer: how much do we not understand Polycomb proteins?The potential roles of EZH2 in regenerative medicine.Epigenetic modifications and long noncoding RNAs influence pancreas development and function.Acinar cell reprogramming: a clinically important target in pancreatic disease.Association between EZH2 expression, silencing of tumor suppressors and disease outcome in solid tumors.NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar-Ductal Transdifferentiation in the Pancreas.Loss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPα.EZH2 in Cancer Progression and Potential Application in Cancer Therapy: A Friend or Foe?Polycomb Repressor Complex 2 in Genomic Instability and CancerSnail cooperates with KrasG12D to promote pancreatic fibrosisSilencing of the Fibroblast growth factor 21 gene is an underlying cause of acinar cell injury in mice lacking MIST1.Immunohistochemical analysis of E-cadherin and zeste homolog 2 expression in endoscopic ultrasound-guided fine-needle aspiration of pancreatic adenocarcinoma.Temporally distinct transcriptional regulation of myocyte dedifferentiation and Myofiber growth during muscle regeneration.Epigenetic regulation of cancer progression by EZH2: from biological insights to therapeutic potential.p21(WAF1) (/Cip1) limits senescence and acinar-to-ductal metaplasia formation during pancreatitis.
P2860
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P2860
EZH2 couples pancreatic regeneration to neoplastic progression.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
EZH2 couples pancreatic regeneration to neoplastic progression.
@ast
EZH2 couples pancreatic regeneration to neoplastic progression.
@en
EZH2 couples pancreatic regeneration to neoplastic progression.
@nl
type
label
EZH2 couples pancreatic regeneration to neoplastic progression.
@ast
EZH2 couples pancreatic regeneration to neoplastic progression.
@en
EZH2 couples pancreatic regeneration to neoplastic progression.
@nl
prefLabel
EZH2 couples pancreatic regeneration to neoplastic progression.
@ast
EZH2 couples pancreatic regeneration to neoplastic progression.
@en
EZH2 couples pancreatic regeneration to neoplastic progression.
@nl
P2093
P2860
P356
P1433
P1476
EZH2 couples pancreatic regeneration to neoplastic progression.
@en
P2093
Alexandra Livanos
George Miller
Jon Mallen-St Clair
Kyoung Eun Lee
Laura Taylor
Raphaël Margueron
Rengin Soydaner-Azeloglu
Yuliya Pylayeva-Gupta
P2860
P304
P356
10.1101/GAD.181800.111
P577
2012-03-01T00:00:00Z