Mutational switch of an IL-6 response to an interferon-gamma-like response. - Wikidata - awgldk - TriplyDB

Mutational switch of an IL-6 response to an interferon-gamma-like response.

Mutational switch of an IL-6 response to an interferon-gamma-like response.

http://www.wikidata.org/entity/Q34031049

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The Sin3a repressor complex is a master regulator of STAT transcriptional activity The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3 Signaling by STATs STAT3 inhibitors for cancer therapy: Have all roads been explored?Constitutive type I interferon modulates homeostatic balance through tonic signaling A novel requirement for Janus kinases as mediators of drug resistance induced by fibroblast growth factor-2 in human cancer cells STAT3 deletion sensitizes cells to oxidative stress Arid5a regulates naive CD4+ T cell fate through selective stabilization of Stat3 mRNA.Stat3 isoforms, alpha and beta, demonstrate distinct intracellular dynamics with prolonged nuclear retention of Stat3beta mapping to its unique C-terminal end.Cannabinoids Delta(9)-tetrahydrocannabinol and cannabidiol differentially inhibit the lipopolysaccharide-activated NF-kappaB and interferon-beta/STAT proinflammatory pathways in BV-2 microglial cells Regulation of signal transducer and activator of transcription 3 enhanceosome formation by apurinic/apyrimidinic endonuclease 1 in hepatic acute phase response.Stat1 and Stat2 but not Stat3 arbitrate contradictory growth signals elicited by alpha/beta interferon in T lymphocytes.Extended anti-inflammatory action of a degradation-resistant mutant of cell-penetrating suppressor of cytokine signaling 3.Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension.Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma.gp130 at the nexus of inflammation, autoimmunity, and cancer.STAT1 deficiency unexpectedly and markedly exacerbates the pathophysiological actions of IFN-alpha in the central nervous system Factors regulated by interferon gamma and hypoxia-inducible factor 1A contribute to responses that protect mice from Coccidioides immitis infection The amino-terminal extensions of the longer Sendai virus C proteins modulate pY701-Stat1 and bulk Stat1 levels independently of interferon signaling.Toxoplasma gondii clonal strains all inhibit STAT1 transcriptional activity but polymorphic effectors differentially modulate IFNγ induced gene expression and STAT1 phosphorylation The clinical and biological significance of STAT1 in esophageal squamous cell carcinoma.Elucidating the crosstalk mechanism between IFN-gamma and IL-6 via mathematical modelling.Monoclonal Antibodies Specific for STAT3β Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer.The use of germ line-mutated mice in understanding host-pathogen interactions.IL-27 and type 2 immunity in asthmatic patients: association with severity, CXCL9, and signal transducer and activator of transcription signaling.Comparative proteomic analysis reveals activation of mucosal innate immune signaling pathways during cholera.High-throughput de novo screening of receptor agonists with an automated single-cell analysis and isolation system.Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs.Modulation of STAT3 folding and function by TRiC/CCT chaperonin.Of JAKs, STATs, blind watchmakers, jeeps and trains.Proapoptotic and antiapoptotic actions of Stat1 versus Stat3 underlie neuroprotective and immunoregulatory functions of IL-11.Dysregulation of janus kinases and signal transducers and activators of transcription in cancer.The Mycoplasma hyorhinis p37 Protein Rapidly Induces Genes in Fibroblasts Associated with Inflammation and Cancer.Opposing roles of STAT1 and STAT3 in IL-21 function in CD4+ T cells STAT1 deficiency redirects IFN signalling toward suppression of TLR response through a feedback activation of STAT3.Impact of the N-Terminal Domain of STAT3 in STAT3-Dependent Transcriptional Activity Human Cytomegalovirus Immediate-Early 1 Protein Rewires Upstream STAT3 to Downstream STAT1 Signaling Switching an IL6-Type to an IFNγ-Like Response Stat3 regulates microtubules by antagonizing the depolymerization activity of stathmin IL-27 Induces Th17 Differentiation in the Absence of STAT1 Signaling High-Throughput Analysis of Mammalian Receptor Tyrosine Kinase Activation in Yeast Cells.

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P2860

Mutational switch of an IL-6 response to an interferon-gamma-like response.

http://www.wikidata.org/entity/Q34031049

description

2002 nî lūn-bûn

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2002 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հունիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

Mutational switch of an IL-6 response to an interferon-gamma-like response.

@ast

Mutational switch of an IL-6 response to an interferon-gamma-like response.

@en

Mutational switch of an IL-6 response to an interferon-gamma-like response.

@nl

type

label

Mutational switch of an IL-6 response to an interferon-gamma-like response.

@ast

Mutational switch of an IL-6 response to an interferon-gamma-like response.

@en

Mutational switch of an IL-6 response to an interferon-gamma-like response.

@nl

prefLabel

Mutational switch of an IL-6 response to an interferon-gamma-like response.

@ast

Mutational switch of an IL-6 response to an interferon-gamma-like response.

@en

Mutational switch of an IL-6 response to an interferon-gamma-like response.

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Mutational switch of an IL-6 response to an interferon-gamma-like response.

@en

P2093

Hayaatun Is'harc

http://www.w3.org/2001/XMLSchema#string

Ian M Kerr

http://www.w3.org/2001/XMLSchema#string

Ida Gesualdo

http://www.w3.org/2001/XMLSchema#string

Sally J Newman

http://www.w3.org/2001/XMLSchema#string

Silvia Tininini

http://www.w3.org/2001/XMLSchema#string

Tonino Alonzi

http://www.w3.org/2001/XMLSchema#string

P2860

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

The distal region and receptor tyrosines of the Epo receptor are non-essential for in vivo erythropoiesis

Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

How cells respond to interferons

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

The IFN gamma receptor: a paradigm for cytokine receptor signaling

A completely foreign receptor can mediate an interferon-gamma-like response.

Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation

Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver.

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8043-8047

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scholarly article

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10.1073/PNAS.122236099

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P407

P433

12

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P478

99

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Joerg F. Schlaak

Ana P Costa-Pereira

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2002-06-01T00:00:00Z

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11313141

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12060750

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123017

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