Cyclin-dependent kinases: a family portrait. - Wikidata - awgldk - TriplyDB

Cyclin-dependent kinases: a family portrait.

Cyclin-dependent kinases: a family portrait.

http://www.wikidata.org/entity/Q34036740

about

The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis The emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancer Hypoxia-Inducible Factors (HIFs) and Phosphorylation: Impact on Stability, Localization, and Transactivity Mediator kinase module and human tumorigenesis Divide and differentiate: CDK/Cyclins and the art of development CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.The Mediator complex and transcription regulation Cyclin-dependent kinase-like function is shared by the beta- and gamma- subset of the conserved herpesvirus protein kinases Molecular basis of differential selectivity of cyclobutyl-substituted imidazole inhibitors against CDKs: insights for rational drug design Palmitoylation-dependent CDKL5-PSD-95 interaction regulates synaptic targeting of CDKL5 and dendritic spine development Tumor-suppressive effects of CDK8 in endometrial cancer cells.Comparative analysis of mRNA isoform expression in cardiac hypertrophy and development reveals multiple post-transcriptional regulatory modules.Comprehensive characterization of (S)GTP-binding proteins by orthogonal quantitative (S)GTP-affinity profiling and (S)GTP/GTP competition assays.Cdk5 activity in the brain - multiple paths of regulation.The kinome of Phytophthora infestans reveals oomycete-specific innovations and links to other taxonomic groups Involvement of cyclin-dependent kinase-like 2 in cognitive function required for contextual and spatial learning in mice.CDK/CK1 inhibitors roscovitine and CR8 downregulate amplified MYCN in neuroblastoma cells.Cyclin-dependent kinases CDK11p58 inhibits ERα-positive breast cancer invasion by targeting integrin β3 via the repression of ERα signaling Phosphatase 1 nuclear targeting subunit is an essential regulator of M-phase entry, maintenance, and exit Nucleolar stress with and without p53.The RNA binding motif protein 15B (RBM15B/OTT3) is a functional competitor of serine-arginine (SR) proteins and antagonizes the positive effect of the CDK11p110-cyclin L2α complex on splicing.Proteomic analysis of the human cyclin-dependent kinase family reveals a novel CDK5 complex involved in cell growth and migration Cyclin-dependent kinase 6 phosphorylates NF-κB P65 at serine 536 and contributes to the regulation of inflammatory gene expression.CDK8: a positive regulator of transcription ATP-noncompetitive CDK inhibitors for cancer therapy: an overview.Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages.Characterization of human cyclin-dependent kinase 12 (CDK12) and CDK13 complexes in C-terminal domain phosphorylation, gene transcription, and RNA processing Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy Phosphoproteomic analysis of the highly-metastatic hepatocellular carcinoma cell line, MHCC97-H Why cyclin Y? A highly conserved cyclin with essential functions Cyclin-dependent kinase 11(p110) (CDK11(p110)) is crucial for human breast cancer cell proliferation and growth Moxifloxacin and ciprofloxacin induces S-phase arrest and augments apoptotic effects of cisplatin in human pancreatic cancer cells via ERK activation PFTK1 Promotes Gastric Cancer Progression by Regulating Proliferation, Migration and Invasion.Overexpression of PFTK1 predicts resistance to chemotherapy in patients with oesophageal squamous cell carcinoma.CDK13, a Kinase Involved in Pre-mRNA Splicing, Is a Component of the Perinucleolar Compartment.Cdk3, a conjugation-specific cyclin-dependent kinase, is essential for the initiation of meiosis in Tetrahymena thermophila.

P2860

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P2860

Cyclin-dependent kinases: a family portrait.

http://www.wikidata.org/entity/Q34036740

description

2009 nî lūn-bûn

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2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Cyclin-dependent kinases: a family portrait.

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Cyclin-dependent kinases: a family portrait.

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Cyclin-dependent kinases: a family portrait.

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Cyclin-dependent kinases: a family portrait.

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Cyclin-dependent kinases: a family portrait.

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Cyclin-dependent kinases: a family portrait.

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Cyclin-dependent kinases: a family portrait.

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Cyclin-dependent kinases: a family portrait.

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Cyclin-dependent kinases: a family portrait.

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Nature Cell Biology

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Cyclin-dependent kinases: a family portrait

@en

P2093

Debra J Wolgemuth

http://www.w3.org/2001/XMLSchema#string

Edward Harlow

http://www.w3.org/2001/XMLSchema#string

Jill M Lahti

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Li-Huei Tsai

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Tim Hunt

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Tony Hunter

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P2860

Towards a proteome-scale map of the human protein–protein interaction network

A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology

Functional characterization of human PFTK1 as a cyclin-dependent kinase

The protein kinase complement of the human genome

A Drosophila protein-interaction map centered on cell-cycle regulators

CDK13/CDC2L5 interacts with L-type cyclins and regulates alternative splicing

Identification and characterization of the CDK12/cyclin L1 complex involved in alternative splicing regulation.

Mammalian cyclin-dependent kinases.

Cell cycle-related kinase: a novel candidate oncogene in human glioblastoma.

p42, a novel cyclin-dependent kinase-activating kinase in mammalian cells.

P2888

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1275-1276

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scholarly article

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10.1038/NCB1109-1275

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11

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11

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Marcos Malumbres

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2009-11-01T00:00:00Z

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38062953

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1025575144

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19884882

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2914104

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