Mechanism of inactivation of human ribonucleotide reductase with p53R2 by gemcitabine 5'-diphosphate
about
Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA ReplicationInactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: covalent modificationOne-electron oxidation of gemcitabine and analogs: mechanism of formation of C3' and C2' sugar radicals.Clofarabine 5'-di and -triphosphates inhibit human ribonucleotide reductase by altering the quaternary structure of its large subunitModulation of the ribonucleotide reductase M1-gemcitabine interaction in vivo by N-ethylmaleimide.Phase I Trial of Carboplatin and Gemcitabine Chemotherapy and Stereotactic Ablative Radiosurgery for the Palliative Treatment of Persistent or Recurrent Gynecologic CancerManagement of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone-induced methemoglobinemia.Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication.Investigation of in vivo diferric tyrosyl radical formation in Saccharomyces cerevisiae Rnr2 protein: requirement of Rnr4 and contribution of Grx3/4 AND Dre2 proteinsSWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer.Targeting the Large Subunit of Human Ribonucleotide Reductase for Cancer Chemotherapy.Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer.Discovery of drugs that possess activity against feline leukemia virusIdentification of Non-nucleoside Human Ribonucleotide Reductase ModulatorsInvestigation of in vivo roles of the C-terminal tails of the small subunit (ββ') of Saccharomyces cerevisiae ribonucleotide reductase: contribution to cofactor formation and intersubunit association within the active holoenzyme.DNA building blocks: keeping control of manufacture.Novel developments in the use of antimetabolites.Deoxyribonucleotide metabolism, mutagenesis and cancer.5-aza-2',2'-Difluroro Deoxycytidine (NUC013): A Novel Nucleoside DNA Methyl Transferase Inhibitor and Ribonucleotide Reductase Inhibitor for the Treatment of CancerSynthesis and cytostatic evaluation of 4-N-alkanoyl and 4-N-alkyl gemcitabine analogues.Human pyrimidine nucleotide biosynthesis as a target for antiviral chemotherapy.Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: adenosylcobalamin destruction and formation of a nucleotide-based radical.Diversity in Overall Activity Regulation of Ribonucleotide Reductase.Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur clusterProton Coupled Electron Transfer and Redox Active Tyrosines: Structure and Function of the Tyrosyl Radicals in Ribonucleotide Reductase and Photosystem II.A ribonucleotide reductase inhibitor with deoxyribonucleoside-reversible cytotoxicity.Insight into the mechanism of inactivation of ribonucleotide reductase by gemcitabine 5'-diphosphate in the presence or absence of reductant.Phylogenetic sequence analysis and functional studies reveal compensatory amino acid substitutions in loop 2 of human ribonucleotide reductase.Structure-Guided Synthesis and Mechanistic Studies Reveal Sweetspots on Naphthyl Salicyl Hydrazone Scaffold as Non-Nucleosidic Competitive, Reversible Inhibitors of Human Ribonucleotide Reductase.Triapine Radiochemotherapy in Advanced Stage Cervical Cancer.
P2860
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P2860
Mechanism of inactivation of human ribonucleotide reductase with p53R2 by gemcitabine 5'-diphosphate
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Mechanism of inactivation of h ...... by gemcitabine 5'-diphosphate
@ast
Mechanism of inactivation of h ...... by gemcitabine 5'-diphosphate
@en
Mechanism of inactivation of h ...... by gemcitabine 5'-diphosphate
@nl
type
label
Mechanism of inactivation of h ...... by gemcitabine 5'-diphosphate
@ast
Mechanism of inactivation of h ...... by gemcitabine 5'-diphosphate
@en
Mechanism of inactivation of h ...... by gemcitabine 5'-diphosphate
@nl
prefLabel
Mechanism of inactivation of h ...... by gemcitabine 5'-diphosphate
@ast
Mechanism of inactivation of h ...... by gemcitabine 5'-diphosphate
@en
Mechanism of inactivation of h ...... by gemcitabine 5'-diphosphate
@nl
P2860
P356
P1433
P1476
Mechanism of inactivation of h ...... by gemcitabine 5'-diphosphate
@en
P2093
JoAnne Stubbe
P2860
P304
11612-11621
P356
10.1021/BI901588Z
P407
P577
2009-12-01T00:00:00Z