A novel cyclic adenosine monophosphate responsive luciferase reporter incorporating a nonpalindromic cyclic adenosine monophosphate response element provides optimal performance for use in G protein coupled receptor drug discovery efforts.
about
Regulation of G protein-coupled receptor signaling: specific dominant-negative effects of melanocortin 2 receptor accessory protein 2A programmable synthetic lineage-control network that differentiates human IPSCs into glucose-sensitive insulin-secreting beta-like cellsRole of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic beta-cells and rat INS-1 cellsDevelopment of an assay for high-throughput energy expenditure monitoring in the zebrafishData for amino acid alignment of Japanese stingray melanocortin receptors with other gnathostome melanocortin receptor sequences, and the ligand selectivity of Japanese stingray melanocortin receptors.Importance of regions outside the cytoplasmic tail of G-protein-coupled receptors for phosphorylation and dephosphorylation.Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion.Adrenocorticotropic Hormone (ACTH) Responses Require Actions of the Melanocortin-2 Receptor Accessory Protein on the Extracellular Surface of the Plasma Membrane.Identification of an MRAP-independent melanocortin-2 receptor: functional expression of the cartilaginous fish, Callorhinchus milii, melanocortin-2 receptor in CHO cells.GPR119 Agonist AS1269574 Activates TRPA1 Cation Channels to Stimulate GLP-1 Secretion.Stimulation of proglucagon gene expression by human GPR119 in enteroendocrine L-cell line GLUTag.A novel role for pigment genes in the stress response in rainbow trout (Oncorhynchus mykiss)Dual Topology of the Melanocortin-2 Receptor Accessory Protein Is StableAdenosine-generating ovarian cancer cells attract myeloid cells which differentiate into adenosine-generating tumor associated macrophages - a self-amplifying, CD39- and CD73-dependent mechanism for tumor immune escapeGlucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells.Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM.Glucose-dependent potentiation of mouse islet insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM.Use of chimeric melanocortin-2 and -4 receptors to identify regions responsible for ligand specificity and dependence on melanocortin 2 receptor accessory protein.Synthesis, characterization and pharmacodynamics of vitamin-B(12)-conjugated glucagon-like peptide-1.Design of Synthetic Promoters for Gene Circuits in Mammalian Cells.Aryl Hydrocarbon Receptor-Interacting Protein (AIP) N-Terminus Gene Mutations Identified in Pituitary Adenoma Patients Alter Protein Stability and Function.Chimeric peptide EP45 as a dual agonist at GLP-1 and NPY2R receptors.
P2860
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P2860
A novel cyclic adenosine monophosphate responsive luciferase reporter incorporating a nonpalindromic cyclic adenosine monophosphate response element provides optimal performance for use in G protein coupled receptor drug discovery efforts.
description
2007 nî lūn-bûn
@nan
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
A novel cyclic adenosine monop ...... ceptor drug discovery efforts.
@ast
A novel cyclic adenosine monop ...... ceptor drug discovery efforts.
@en
A novel cyclic adenosine monop ...... ceptor drug discovery efforts.
@nl
type
label
A novel cyclic adenosine monop ...... ceptor drug discovery efforts.
@ast
A novel cyclic adenosine monop ...... ceptor drug discovery efforts.
@en
A novel cyclic adenosine monop ...... ceptor drug discovery efforts.
@nl
prefLabel
A novel cyclic adenosine monop ...... ceptor drug discovery efforts.
@ast
A novel cyclic adenosine monop ...... ceptor drug discovery efforts.
@en
A novel cyclic adenosine monop ...... ceptor drug discovery efforts.
@nl
P2860
P356
P1476
A novel cyclic adenosine monop ...... ceptor drug discovery efforts.
@en
P2093
George G Holz
Oleg G Chepurny
P2860
P304
P356
10.1177/1087057107301856
P577
2007-05-16T00:00:00Z