Clinical use of topoisomerase I inhibitors in anticancer treatment.

Clinical use of topoisomerase I inhibitors in anticancer treatment.

Item
http://www.wikidata.org/entity/Q34056907
TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivoLocking the DNA topoisomerase I protein clamp inhibits DNA rotation and induces cell lethality.Pharmacological management of Ewing sarcoma family of tumours.New drugs for the treatment of metastatic or refractory soft tissue sarcomas in children.Single-molecule observations of topotecan-mediated TopIB activity at a unique DNA sequence.Topoisomerase I levels in the NCI-60 cancer cell line panel determined by validated ELISA and microarray analysis and correlation with indenoisoquinoline sensitivityHuman RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition.Current and future management strategies for relapsed or progressive hepatoblastoma.Gefitinib enhances the antitumor activity of CPT-11 in vitro and in vivo by inhibiting ABCG2 but not ABCB1: a new clue to circumvent gastrointestinal toxicity risk.A single mutation in the 729 residue modulates human DNA topoisomerase IB DNA binding and drug resistance.Topotecan-filgrastim combination is an effective regimen for mobilizing peripheral blood stem cells.Platinated DNA adducts enhance poisoning of DNA topoisomerase I by camptothecin.Substitution of conserved residues within the active site alters the cleavage religation equilibrium of DNA topoisomerase I.Defects in SUMO (small ubiquitin-related modifier) conjugation and deconjugation alter cell sensitivity to DNA topoisomerase I-induced DNA damage.
P2860

Clinical use of topoisomerase I inhibitors in anticancer treatment.

Item
http://www.wikidata.org/entity/Q34056907
description
2000 nî lūn-bûn
@nan
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Clinical use of topoisomerase I inhibitors in anticancer treatment.
@ast
Clinical use of topoisomerase I inhibitors in anticancer treatment.
@en
Clinical use of topoisomerase I inhibitors in anticancer treatment.
@nl
type
label
Clinical use of topoisomerase I inhibitors in anticancer treatment.
@ast
Clinical use of topoisomerase I inhibitors in anticancer treatment.
@en
Clinical use of topoisomerase I inhibitors in anticancer treatment.
@nl
prefLabel
Clinical use of topoisomerase I inhibitors in anticancer treatment.
@ast
Clinical use of topoisomerase I inhibitors in anticancer treatment.
@en
Clinical use of topoisomerase I inhibitors in anticancer treatment.
@nl
P1433
P1476
P2093
P2860
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P31
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P433
P478
P577
P698
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P1433
P1476
Clinical use of topoisomerase I inhibitors in anticancer treatment.
@en
P2093
P2860
P304
P31
P356
10.1002/1096-911X(20001001)35:4<385::AID-MPO1>3.0.CO;2-E
P433
P478
P577
P698