Induction of p53-dependent and p53-independent cellular responses by topoisomerase 1 inhibitors
about
Effect of non-steroidal anti-inflammatory drugs on colon carcinoma Caco-2 cell responsiveness to topoisomerase inhibitor drugsExpression of p57(KIP2) potently blocks the growth of human astrocytomas and induces cell senescencePregnane X Receptor (PXR) expression in colorectal cancer cells restricts irinotecan chemosensitivity through enhanced SN-38 glucuronidation.Clinical use of topoisomerase I inhibitors in anticancer treatment.Defective p53 antiangiogenic signaling in glioblastoma.Altered processing of amyloid precursor protein in cells undergoing apoptosis.UCN-01 induces S and G2/M cell cycle arrest through the p53/p21(waf1) or CHK2/CDC25C pathways and can suppress invasion in human hepatoma cell lines.Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model.Schedule-dependent activity of 5-fluorouracil and irinotecan combination in the treatment of human colorectal cancer: in vitro evidence and a phase I dose-escalating clinical trial.Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status.Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin is p53-independentCamptothecin induces apoptosis of human retinoblastoma cells via activation of FOXO1.P53 and p38 MAPK pathways are involved in MONCPT-induced cell cycle G2/M arrest in human non-small cell lung cancer A549.Inhibition of hypoxia inducible factor 1 and topoisomerase with acriflavine sensitizes perihilar cholangiocarcinomas to photodynamic therapy.Heterogeneous cell response to topotecan in a CFSE-based proliferation test.Cellular effects of CPT-11 on colon carcinoma cells: dependence on p53 and hMLH1 status.Enhanced tumor killing by Apo2L/TRAIL and CPT-11 co-treatment is associated with p21 cleavage and differential regulation of Apo2L/TRAIL ligand and its receptors.Replication and cytolysis of an E1B-attenuated adenovirus in drug-resistant ovarian tumour cells is associated with reduced apoptosis.The molecular mechanisms of Tanshinone IIA on the apoptosis and arrest of human esophageal carcinoma cells.A Novel HSP90 Inhibitor-Drug Conjugate to SN38 Is Highly Effective in Small Cell Lung Cancer.Intraperitoneal adenovirus-mediated suicide gene therapy in combination with either topotecan or paclitaxel in nude mice with human ovarian cancer.Lack of Bax expression is associated with irinotecan-based treatment activity in advanced colorectal cancer patients.
P2860
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P2860
Induction of p53-dependent and p53-independent cellular responses by topoisomerase 1 inhibitors
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Induction of p53-dependent and ...... by topoisomerase 1 inhibitors
@ast
Induction of p53-dependent and ...... by topoisomerase 1 inhibitors
@en
type
label
Induction of p53-dependent and ...... by topoisomerase 1 inhibitors
@ast
Induction of p53-dependent and ...... by topoisomerase 1 inhibitors
@en
prefLabel
Induction of p53-dependent and ...... by topoisomerase 1 inhibitors
@ast
Induction of p53-dependent and ...... by topoisomerase 1 inhibitors
@en
P2860
P356
P1476
Induction of p53-dependent and ...... by topoisomerase 1 inhibitors
@en
P2093
P2860
P2888
P304
P356
10.1038/BJC.1998.571
P407
P577
1998-09-01T00:00:00Z