Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex.
about
Specificity of interaction of INI1/hSNF5 with retroviral integrases and its functional significanceAcetylation of HIV-1 integrase by p300 regulates viral integration.DNA binding induces dissociation of the multimeric form of HIV-1 integrase: a time-resolved fluorescence anisotropy studyHIV-1 integrase crosslinked oligomers are active in vitroHuman immunodeficiency virus type 1 preintegration complexes: studies of organization and compositionCurrent perspectives on HIV-1 antiretroviral drug resistanceStructural basis for functional tetramerization of lentiviral integraseStructure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug designCrystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA bindingStructure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein.A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75A possible role for the asymmetric C-terminal domain dimer of Rous sarcoma virus integrase in viral DNA bindingRetroviral Integrase: Then and NowHuman immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes.Inhibition of human immunodeficiency virus integrase by bis-catecholsIdentification of a hexapeptide inhibitor of the human immunodeficiency virus integrase protein by using a combinatorial chemical libraryA symmetric region of the HIV-1 integrase dimerization interface is essential for viral replicationRetroviral DNA IntegrationBiochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase.Dissecting the role of the N-terminal domain of human immunodeficiency virus integrase by trans-complementation analysisHIV virions as nanoscopic test tubes for probing oligomerization of the integrase enzyme.Structural basis for HIV-1 DNA integration in the human genome, role of the LEDGF/P75 cofactorArchitecture of a full-length retroviral integrase monomer and dimer, revealed by small angle X-ray scattering and chemical cross-linkingAn allosteric mechanism for inhibiting HIV-1 integrase with a small molecule.Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA bindingIrreversible inhibition of human immunodeficiency virus type 1 integrase by dicaffeoylquinic acids.Monoclonal antibodies against the minimal DNA-binding domain in the carboxyl-terminal region of human immunodeficiency virus type 1 integrase.Critical appraisal of elvitegravir in the treatment of HIV-1/AIDS.A Ty1 integrase nuclear localization signal required for retrotranspositionGenetic analyses of DNA-binding mutants in the catalytic core domain of human immunodeficiency virus type 1 integrase.Mapping viral DNA specificity to the central region of integrase by using functional human immunodeficiency virus type 1/visna virus chimeric proteinsEfficient gap repair catalyzed in vitro by an intrinsic DNA polymerase activity of human immunodeficiency virus type 1 integrase.A map of interactions between the proteins of a retrotransposonRetroviral DNA integration.Integrase-lexA fusion proteins incorporated into human immunodeficiency virus type 1 that contains a catalytically inactive integrase gene are functional to mediate integrationElite suppressors harbor low levels of integrated HIV DNA and high levels of 2-LTR circular HIV DNA compared to HIV+ patients on and off HAART.Complementation of integrase function in HIV-1 virions.Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking.Transposase makes critical contacts with, and is stimulated by, single-stranded DNA at the P element termini in vitro.Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction.
P2860
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P2860
Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex.
description
1993 nî lūn-bûn
@nan
1993 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
name
Identification of discrete fun ...... an active multimeric complex.
@ast
Identification of discrete fun ...... an active multimeric complex.
@en
Identification of discrete fun ...... an active multimeric complex.
@nl
type
label
Identification of discrete fun ...... an active multimeric complex.
@ast
Identification of discrete fun ...... an active multimeric complex.
@en
Identification of discrete fun ...... an active multimeric complex.
@nl
prefLabel
Identification of discrete fun ...... an active multimeric complex.
@ast
Identification of discrete fun ...... an active multimeric complex.
@en
Identification of discrete fun ...... an active multimeric complex.
@nl
P2093
P2860
P1433
P1476
Identification of discrete fun ...... an active multimeric complex.
@en
P2093
P2860
P304
P407
P577
1993-08-01T00:00:00Z