Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST).
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Autophagy and cancerAutophagy modulation as a target for anticancer drug discoveryMechanisms of disseminated cancer cell dormancy: an awakening fieldThe multifaceted roles of autophagy in tumors-implications for breast cancer.Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanismNanomaterials and autophagy: new insights in cancer treatmentRNA-dependent protein kinase is essential for 2-methoxyestradiol-induced autophagy in osteosarcoma cellsInduction of autophagy is an early response to gefitinib and a potential therapeutic target in breast cancerAutophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3Autophagic flux determines cell death and survival in response to Apo2L/TRAIL (dulanermin).Increased KIT inhibition enhances therapeutic efficacy in gastrointestinal stromal tumorOxidative DNA double strand breaks and autophagy in the antitumor effect of sterically hindered platinum(II) complexes in NSCLCsExpression of autophagy related proteins in invasive lobular carcinoma: comparison to invasive ductal carcinoma.Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagyNew therapeutic targets in soft tissue sarcoma.Autophagy inhibition sensitizes hepatocellular carcinoma to the multikinase inhibitor linifanib.Imaging the intracellular distribution of tyrosine kinase inhibitors in living cells with quantitative hyperspectral stimulated Raman scatteringCombined efficacy of cediranib and quinacrine in glioma is enhanced by hypoxia and causally linked to autophagic vacuole accumulation.Gastrointestinal stromal tumor - an evolving concept.Knockdown of autophagy-related protein 5, ATG5, decreases oxidative stress and has an opposing effect on camptothecin-induced cytotoxicity in osteosarcoma cellsNoncoding RNA blockade of autophagy is therapeutic in medullary thyroid cancerInhibition of KIT-glycosylation by 2-deoxyglucose abrogates KIT-signaling and combination with ABT-263 synergistically induces apoptosis in gastrointestinal stromal tumor.ZNF32 inhibits autophagy through the mTOR pathway and protects MCF-7 cells from stimulus-induced cell death.The dynamic nature of autophagy in cancerAutophagy as a therapeutic target in cancer.Targeting Disease Persistence in Gastrointestinal Stromal TumorsFAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors.Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1.Autophagy-dependent senescence in response to DNA damage and chronic apoptotic stress.Therapeutic implications of autophagy-mediated cell survival in gastrointestinal stromal tumor after treatment with imatinib mesylate.Interferon-γ induces autophagy with growth inhibition and cell death in human hepatocellular carcinoma (HCC) cells through interferon-regulatory factor-1 (IRF-1)Unfolded protein response to autophagy as a promising druggable target for anticancer therapy.Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell linesTargeting autophagy enhances the anti-tumoral action of crizotinib in ALK-positive anaplastic large cell lymphoma.Regulation of tumor cell dormancy by tissue microenvironments and autophagy.Simalikalactone E (SkE), a new weapon in the armamentarium of drugs targeting cancers that exhibit constitutive activation of the ERK pathway.Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes.Expression of autophagy-related proteins in phyllodes tumor.Therapeutic targeting of autophagy in disease: biology and pharmacology.Reintroduction of imatinib in GIST
P2860
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P2860
Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST).
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Autophagy inhibition and antim ...... testinal stromal tumor (GIST).
@ast
Autophagy inhibition and antim ...... testinal stromal tumor (GIST).
@en
Autophagy inhibition and antim ...... gastrointestinal stromal tumor
@nl
type
label
Autophagy inhibition and antim ...... testinal stromal tumor (GIST).
@ast
Autophagy inhibition and antim ...... testinal stromal tumor (GIST).
@en
Autophagy inhibition and antim ...... gastrointestinal stromal tumor
@nl
prefLabel
Autophagy inhibition and antim ...... testinal stromal tumor (GIST).
@ast
Autophagy inhibition and antim ...... testinal stromal tumor (GIST).
@en
Autophagy inhibition and antim ...... gastrointestinal stromal tumor
@nl
P2093
P2860
P50
P356
P1476
Autophagy inhibition and antim ...... testinal stromal tumor (GIST).
@en
P2093
Alexander J F Lazar
Brian P Rubin
David Reynoso
James McMahon
John C McAuliffe
Jonathan A Trent
Srirupa Roy
Takahiro Taguchi
Wei-Lien Wang
P2860
P304
14333-14338
P356
10.1073/PNAS.1000248107
P407
P577
2010-07-26T00:00:00Z