Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation - Wikidata - awgldk - TriplyDB

Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation

Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation

http://www.wikidata.org/entity/Q34079079

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Blood transcriptomics: applications in toxicology Circulating mitochondrial biomarkers for drug-induced liver injury Pathogenesis of idiosyncratic drug-induced liver injury and clinical perspectives.Predose and Postdose Blood Gene Expression Profiles Identify the Individuals Susceptible to Acetaminophen-Induced Liver Injury in Rats Analysis of the transcriptome in molecular epidemiology studies Use of transcriptomics in understanding mechanisms of drug-induced toxicity Mechanisms of drug-induced liver injury: from bedside to bench.Identification of a metabolic biomarker panel in rats for prediction of acute and idiosyncratic hepatotoxicity.Understanding lactic acidosis in paracetamol (acetaminophen) poisoning.The proper use of acetaminophen.Identification and characterization of adverse effects in 21st century toxicology Translational biomarkers of acetaminophen-induced acute liver injury Identification of Identical Transcript Changes in Liver and Whole Blood during Acetaminophen Toxicity.Blood transcript immune signatures distinguish a subset of people with elevated serum ALT from others given acetaminophen The application of metabonomics to predict drug-induced liver injury.The potential of cytokines as safety biomarkers for drug-induced liver injury.Transcriptional profiling to identify biomarkers of disease and drug response.Assessment of nonsteroidal anti-inflammatory drug-induced hepatotoxicity.Pharmacogenetics and individualized therapy in children: immunosuppressants, antidepressants, anticancer and anti-inflammatory drugs.The generation, detection, and effects of reactive drug metabolites.Contributions of pharmacogenetics and transcriptomics to the understanding of the hypersensitivity drug reactions.The importance of the ionic product for water to understand the physiology of the acid-base balance in humans.Transcriptomic studies on liver toxicity of acetaminophen.Contribution of new technologies to characterization and prediction of adverse effects.A descriptive analysis of aspartate and alanine aminotransferase rise and fall following acetaminophen overdose.Rational Design of Novel Pyridinol-Fused Ring Acetaminophen Analogues CSH guidelines for the diagnosis and treatment of drug-induced liver injury Identification of urinary microRNA profiles in rats that may diagnose hepatotoxicity.Antidote removal during haemodialysis for massive acetaminophen overdose.Dissecting the molecular pathophysiology of drug-induced liver injury.Characterizing the protective effects of SHLP2, a mitochondrial-derived peptide, in macular degeneration

P2860

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P2860

Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation

http://www.wikidata.org/entity/Q34079079

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Acetaminophen dosing of humans ...... ired oxidative phosphorylation

@ast

Acetaminophen dosing of humans ...... ired oxidative phosphorylation

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Acetaminophen dosing of humans ...... ired oxidative phosphorylation

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type

label

Acetaminophen dosing of humans ...... ired oxidative phosphorylation

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Acetaminophen dosing of humans ...... ired oxidative phosphorylation

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Acetaminophen dosing of humans ...... ired oxidative phosphorylation

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prefLabel

Acetaminophen dosing of humans ...... ired oxidative phosphorylation

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Acetaminophen dosing of humans ...... ired oxidative phosphorylation

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Acetaminophen dosing of humans ...... ired oxidative phosphorylation

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Acetaminophen dosing of humans ...... ired oxidative phosphorylation

@en

P2093

Jack Newton

http://www.w3.org/2001/XMLSchema#string

Jason H Winnike

http://www.w3.org/2001/XMLSchema#string

Jeffrey Macdonald

http://www.w3.org/2001/XMLSchema#string

Joel Parker

http://www.w3.org/2001/XMLSchema#string

Kevin Gerrish

http://www.w3.org/2001/XMLSchema#string

Mark Russo

http://www.w3.org/2001/XMLSchema#string

Paul B Watkins

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Richard S Paules

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Rick D Fannin

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Ruchir Shah

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P2860

Isolated complex I deficiency in children: clinical, biochemical and genetic aspects

Singular value decomposition for genome-wide expression data processing and modeling

Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States.

The Immunological Genome Project: networks of gene expression in immune cells.

Blood gene expression signatures predict exposure levels.

Intracellular signaling mechanisms of acetaminophen-induced liver cell death.

Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype.

Mitochondrial complex III regulates hypoxic activation of HIF.

Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival.

Lactic acidosis and mitochondrial disorders.

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227-236

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scholarly article

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10.1002/HEP.23330

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P433

1

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51

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2010-01-01T00:00:00Z

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38094785

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19918972

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phosphorylation

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2925683

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