Tissue specific expression of p53 target genes suggests a key role for KILLER/DR5 in p53-dependent apoptosis in vivo.
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Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growthSSRP1 functions as a co-activator of the transcriptional activator p63Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeuticsSilencing of the novel p53 target gene Snk/Plk2 leads to mitotic catastrophe in paclitaxel (taxol)-exposed cellsIdentification and characterization of the cytoplasmic protein TRAF4 as a p53-regulated proapoptotic geneBID regulation by p53 contributes to chemosensitivityFollowing a TRAIL: update on a ligand and its five receptorsApoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.Transcriptional up-regulation and activation of initiating caspases in experimental glaucomaGarcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins.DR5 knockout mice are compromised in radiation-induced apoptosisThe Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor.p53-Dependent and p53-independent induction of insulin-like growth factor binding protein-3 by deoxyribonucleic acid damage and hypoxia.A bioinformatics filtering strategy for identifying radiation response biomarker candidates.Integrative genomics revealed RAI3 is a cell growth-promoting gene and a novel P53 transcriptional target.Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy.KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genesInsights into cancer therapeutic design based on p53 and TRAIL receptor signaling.ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins.An exploratory evaluation of the utility of transcriptional and urinary kidney injury biomarkers for the prediction of aristolochic acid-induced renal injury in male rats.Molecular mechanisms of irradiation-induced apoptosisThe role of p53 in determining sensitivity to radiotherapy.p53 downstream targets and chemosensitivity.Phosphorylation of serine 18 regulates distinct p53 functions in miceThe role of p53 in chemosensitivity and radiosensitivity.Using targeted transgenic reporter mice to study promoter-specific p53 transcriptional activity.Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins.Insulin-like growth factor factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signaling.New insights into germ cell migration and survival/apoptosis in spermatogenesis: Lessons from CD147.Candidate protein biodosimeters of human exposure to ionizing radiation.The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss.Gamma-radiation (GR) triggers a unique gene expression profile associated with cell death compared to proton radiation (PR) in mice in vivo.Microenvironmental and genetic factors in haemopoietic radiation responses.p53 and PUMA independently regulate apoptosis of intestinal epithelial cells in patients and mice with colitisMechanisms of radiation toxicity in transformed and non-transformed cellsDownregulation of a novel human gene, ROGDI, increases radiosensitivity in cervical cancer cells.Role of caspase-8 in thymus function.The fermented non-digestible fraction of common bean (Phaseolus vulgaris L.) triggers cell cycle arrest and apoptosis in human colon adenocarcinoma cells.Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity.Links between innate immunity and normal tissue radiobiology.
P2860
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P2860
Tissue specific expression of p53 target genes suggests a key role for KILLER/DR5 in p53-dependent apoptosis in vivo.
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
Tissue specific expression of ...... 3-dependent apoptosis in vivo.
@ast
Tissue specific expression of ...... 3-dependent apoptosis in vivo.
@en
Tissue specific expression of ...... 3-dependent apoptosis in vivo.
@nl
type
label
Tissue specific expression of ...... 3-dependent apoptosis in vivo.
@ast
Tissue specific expression of ...... 3-dependent apoptosis in vivo.
@en
Tissue specific expression of ...... 3-dependent apoptosis in vivo.
@nl
prefLabel
Tissue specific expression of ...... 3-dependent apoptosis in vivo.
@ast
Tissue specific expression of ...... 3-dependent apoptosis in vivo.
@en
Tissue specific expression of ...... 3-dependent apoptosis in vivo.
@nl
P2860
P356
P1433
P1476
Tissue specific expression of ...... 53-dependent apoptosis in vivo
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204484
P407
P577
2001-08-01T00:00:00Z
P5875
P6179
1031541989