ERG deregulation induces PIM1 over-expression and aneuploidy in prostate epithelial cells.
about
PIM1 kinase as a target for cancer therapyThe role of PIM1/PIM2 kinases in tumors of the male reproductive systemExpression of ERG protein in prostate cancer: variability and biological correlates.Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia.Androgen receptor and gene network: Micromechanics reassemble the signaling machinery of TMPRSS2-ERG positive prostate cancer cells.B-lineage transcription factors and cooperating gene lesions required for leukemia development.PIM1 kinase as a promise of targeted therapy in prostate cancer stem cellsBCR/ABL1 and BCR are under the transcriptional control of the MYC oncogeneERG deregulation induces IGF-1R expression in prostate cancer cells and affects sensitivity to anti-IGF-1R agents.Discovery and identification of PIM-1 kinase inhibitors through a hybrid screening approach.A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors.Emergence of ETS transcription factors as diagnostic tools and therapeutic targets in prostate cancer.The Novel PIM1 Inhibitor NMS-P645 Reverses PIM1-Dependent Effects on TMPRSS2/ERG Positive Prostate Cancer Cells And Shows Anti-Proliferative Activity in Combination with PI3K Inhibition.TMPRSS2-ERG fusion protein regulates insulin-like growth factor-1 receptor (IGF1R) gene expression in prostate cancer: involvement of transcription factor Sp1.Monoallelic expression of TMPRSS2/ERG in prostate cancer stem cells.Oncogenic fusion proteins adopt the insulin-like growth factor signaling pathway.Fibroblast growth factor receptor signaling plays a key role in transformation induced by the TMPRSS2/ERG fusion gene and decreased PTEN.
P2860
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P2860
ERG deregulation induces PIM1 over-expression and aneuploidy in prostate epithelial cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
ERG deregulation induces PIM1 ...... in prostate epithelial cells.
@ast
ERG deregulation induces PIM1 ...... in prostate epithelial cells.
@en
ERG deregulation induces PIM1 ...... in prostate epithelial cells.
@nl
type
label
ERG deregulation induces PIM1 ...... in prostate epithelial cells.
@ast
ERG deregulation induces PIM1 ...... in prostate epithelial cells.
@en
ERG deregulation induces PIM1 ...... in prostate epithelial cells.
@nl
prefLabel
ERG deregulation induces PIM1 ...... in prostate epithelial cells.
@ast
ERG deregulation induces PIM1 ...... in prostate epithelial cells.
@en
ERG deregulation induces PIM1 ...... in prostate epithelial cells.
@nl
P2093
P2860
P50
P1433
P1476
ERG deregulation induces PIM1 ...... in prostate epithelial cells.
@en
P2093
Giorgio Bovo
Guido Strada
James Frances Reid
Luca Mologni
Marco Grasso
Michela Viltadi
Rocco Piazza
Sara Redaelli
Stefano Sanselicio
P2860
P304
P356
10.1371/JOURNAL.PONE.0028162
P407
P577
2011-11-30T00:00:00Z