A norovirus protease structure provides insights into active and substrate binding site integrity
about
Structures of the compact helical core domains of feline calicivirus and murine norovirus VPg proteinsA Structural Study of Norovirus 3C Protease Specificity: Binding of a Designed Active Site-Directed Peptide InhibitorBroad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, noroviruses, and coronaviruses.Structural and dynamics characterization of norovirus proteaseStructural Basis of Substrate Specificity and Protease Inhibition in Norwalk VirusStructure of a Murine Norovirus NS6 Protease-Product Complex Revealed by Adventitious CrystallisationFeline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 CleavageAntiviral targets of human norovirusesExpression of the murine norovirus (MNV) ORF1 polyprotein is sufficient to induce apoptosis in a virus-free cell model.Characterization and inhibition of norovirus proteases of genogroups I and II using a fluorescence resonance energy transfer assay.The p4-p2' amino acids surrounding human norovirus polyprotein cleavage sites define the core sequence regulating self-processing order.Crystallization and preliminary X-ray diffraction analysis of the protease from Southampton norovirus complexed with a Michael acceptor inhibitor.X-ray crystallographic structure of the Norwalk virus protease at 1.5-A resolution.Cleavage map and proteolytic processing of the murine norovirus nonstructural polyprotein in infected cells.Design, synthesis, and evaluation of inhibitors of Norwalk virus 3C protease.Highly conserved configuration of catalytic amino acid residues among calicivirus-encoded proteases.Potent inhibition of norovirus 3CL protease by peptidyl α-ketoamides and α-ketoheterocycles.Structural basis for specific recognition of substrates by sapovirus protease.Substrate specificity of Tulane virus protease.Potent inhibition of norovirus by dipeptidyl α-hydroxyphosphonate transition state mimics.Current tools for norovirus drug discoveryAnti-norovirus therapeutics: a patent review (2010-2015).Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus.Recent Advances in the Discovery of Norovirus Therapeutics.Glutamyl Endopeptidases: The Puzzle of Substrate SpecificityA Cell-based Fluorescence Resonance Energy Transfer (FRET) Sensor Reveals Inter- and Intragenogroup Variations in Norovirus Protease Activity and Polyprotein Cleavage.Model systems for the study of human norovirus Biology.Structure determination of Murine Norovirus NS6 proteases with C-terminal extensions designed to probe protease-substrate interactions.Structural and inhibitor studies of norovirus 3C-like proteases.Crystallization and X-ray analysis of 23 nm virus-like particles from Norovirus Chiba strain.Structural and functional characterization of sapovirus RNA-dependent RNA polymerase.Structure-based design and functional studies of novel noroviral 3C protease chimaeras offer insights into substrate specificity.Backbone and side-chain ¹H, ¹⁵N, and ¹³C resonance assignments of Norwalk virus protease.Structure and Function of Caliciviral RNA Polymerases.Selection and Characterization of Rupintrivir-Resistant Norwalk Virus Replicon Cells In Vitro.
P2860
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P2860
A norovirus protease structure provides insights into active and substrate binding site integrity
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
A norovirus protease structure ...... bstrate binding site integrity
@ast
A norovirus protease structure ...... bstrate binding site integrity
@en
A norovirus protease structure ...... bstrate binding site integrity
@nl
type
label
A norovirus protease structure ...... bstrate binding site integrity
@ast
A norovirus protease structure ...... bstrate binding site integrity
@en
A norovirus protease structure ...... bstrate binding site integrity
@nl
prefLabel
A norovirus protease structure ...... bstrate binding site integrity
@ast
A norovirus protease structure ...... bstrate binding site integrity
@en
A norovirus protease structure ...... bstrate binding site integrity
@nl
P2093
P2860
P1433
P1476
A norovirus protease structure ...... bstrate binding site integrity
@en
P2093
Kentaro Nakamura
Masaki Yamamoto
Naokazu Takeda
Nobuo Tanaka
Takao Sato
Takashi Kumasaka
Tatsuo Miyamura
Yuichi Someya
P2860
P304
13685-13693
P356
10.1128/JVI.79.21.13685-13693.2005
P407
P577
2005-11-01T00:00:00Z