MicroRNA-1 and -133 increase arrhythmogenesis in heart failure by dissociating phosphatase activity from RyR2 complex. - Wikidata - awgldk - TriplyDB

MicroRNA-1 and -133 increase arrhythmogenesis in heart failure by dissociating phosphatase activity from RyR2 complex.

MicroRNA-1 and -133 increase arrhythmogenesis in heart failure by dissociating phosphatase activity from RyR2 complex.

http://www.wikidata.org/entity/Q34097829

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Counteracting Protein Kinase Activity in the Heart: The Multiple Roles of Protein Phosphatases Roles of the canonical myomiRs miR-1, -133 and -206 in cell development and disease MicroRNAs in heart failure: Small molecules with major impact Differential expression of microRNAs in different disease states.Differential expression of dicer, miRNAs, and inflammatory markers in diabetic Ins2+/- Akita hearts Role of RyR2 phosphorylation in heart failure and arrhythmias: Controversies around ryanodine receptor phosphorylation in cardiac disease.Exosomes: Fundamental Biology and Roles in Cardiovascular Physiology Profiles of extracellular miRNAs in the aqueous humor of glaucoma patients assessed with a microarray system Role of microRNA-1 in human cancer and its therapeutic potentials.let-7e replacement yields potent anti-arrhythmic efficacy via targeting beta 1-adrenergic receptor in rat heart MicroRNAs and cardiac sarcoplasmic reticulum calcium ATPase-2 in human myocardial infarction: expression and bioinformatic analysis.MiRNA-1/133a clusters regulate adrenergic control of cardiac repolarization A heterozygous variant in the human cardiac miR-133 gene, MIR133A2, alters miRNA duplex processing and strand abundance Cardiac function is regulated by B56α-mediated targeting of protein phosphatase 2A (PP2A) to contractile relevant substrates.MicroRNA-1 downregulation increases connexin 43 displacement and induces ventricular tachyarrhythmias in rodent hypertrophic hearts.A panel of 4 microRNAs facilitates the prediction of left ventricular contractility after acute myocardial infarction.Dietary omega-3 fatty acids promote arrhythmogenic remodeling of cellular Ca2+ handling in a postinfarction model of sudden cardiac death Differential expression of microRNAs in ischemic heart disease.Hyperphosphorylation of RyRs underlies triggered activity in transgenic rabbit model of LQT2 syndrome.Downregulation of connexin43 by microRNA-130a in cardiomyocytes results in cardiac arrhythmias.Human circulating microRNA-1 and microRNA-126 as potential novel indicators for acute myocardial infarction.Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy Biological significance of miR-126 expression in atrial fibrillation and heart failure.Protein phosphatase 2A regulatory subunit B56α limits phosphatase activity in the heart.The Role of MicroRNAs in Antiarrhythmic Therapy for Atrial Fibrillation.Molecular mechanisms underlying cardiac protein phosphatase 2A regulation in heart.The altered expression profile of microRNAs in cardiopulmonary bypass canine models and the effects of mir-499 on myocardial ischemic reperfusion injury.Genetics and epigenetics of arrhythmia and heart failure.A feedback circuit between miR-133 and the ERK1/2 pathway involving an exquisite mechanism for regulating myoblast proliferation and differentiation.Exercise mediated protection of diabetic heart through modulation of microRNA mediated molecular pathways Sarcoplasmic reticulum Ca²⁺ release is both necessary and sufficient for SK channel activation in ventricular myocytes.Cardiovascular microRNAs: as modulators and diagnostic biomarkers of diabetic heart disease.Ca handling during excitation-contraction coupling in heart failure.MicroRNAs in heart failure: Non-coding regulators of metabolic function.MicroRNA regulation of cardiac conduction and arrhythmias MicroRNAs in heart failure: new targets in disease management.Roles of Calcium Regulating MicroRNAs in Cardiac Ischemia-Reperfusion Injury.Looking into a conceptual framework of ROS-miRNA-atrial fibrillation.Regulation of Ca(2+) transient by PP2A in normal and failing heart.The Interplay between PP2A and microRNAs in Leukemia.

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P2860

MicroRNA-1 and -133 increase arrhythmogenesis in heart failure by dissociating phosphatase activity from RyR2 complex.

http://www.wikidata.org/entity/Q34097829

description

2011 nî lūn-bûn

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2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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MicroRNA-1 and -133 increase a ...... se activity from RyR2 complex.

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MicroRNA-1 and -133 increase a ...... se activity from RyR2 complex.

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MicroRNA-1 and -133 increase a ...... se activity from RyR2 complex.

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MicroRNA-1 and -133 increase a ...... se activity from RyR2 complex.

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MicroRNA-1 and -133 increase a ...... se activity from RyR2 complex.

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MicroRNA-1 and -133 increase a ...... se activity from RyR2 complex.

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MicroRNA-1 and -133 increase a ...... se activity from RyR2 complex.

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MicroRNA-1 and -133 increase a ...... se activity from RyR2 complex.

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MicroRNA-1 and -133 increase a ...... se activity from RyR2 complex.

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JOURNAL.PONE.0028324

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MicroRNA-1 and -133 increase a ...... se activity from RyR2 complex.

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Andriy E Belevych

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Dmitry Terentyev

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Hitesh K Jindal

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Hsiang-Ting Ho

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Jennifer A Rochira

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Maha Abdellatif

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Mickey M Martin

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Radmila Terentyeva

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Sandor Györke

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Sarah E Sansom

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P2860

MicroRNAs: target recognition and regulatory functions

MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2

MicroRNA-1 downregulation by propranolol in a rat model of myocardial infarction: a new mechanism for ischaemic cardioprotection

Cellular basis of triggered arrhythmias in heart failure

Changes in microRNA-1 expression and IK1 up-regulation in human atrial fibrillation

MicroRNAs miR-1, miR-133a, miR-133b and miR-208 are dysregulated in human myocardial infarction

Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart

The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2

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12

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Cynthia A Carnes

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