Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response. - Wikidata - awgldk - TriplyDB

Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response.

Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response.

http://www.wikidata.org/entity/Q34099551

about

Repeated phosphopeptide motifs in human Claspin are phosphorylated by Chk1 and mediate Claspin function Cell cycle-dependent formation of Cdc45-Claspin complexes in human cells is compromized by UV-mediated DNA damage Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint Characterization of functional domains in human Claspin Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint Claspin promotes normal replication fork rates in human cells DNA polymerase ε and its roles in genome stability The high fidelity and unique error signature of human DNA polymerase epsilon Rad17 plays a central role in establishment of the interaction between TopBP1 and the Rad9-Hus1-Rad1 complex at stalled replication forks Drf1-dependent kinase interacts with Claspin through a conserved protein motif.A genetic screen for replication initiation defective (rid) mutants in Schizosaccharomyces pombe IKK and NF-kappaB-mediated regulation of Claspin impacts on ATR checkpoint function.The structural determinants of checkpoint activation Site-specific phosphorylation of a checkpoint mediator protein controls its responses to different DNA structures Tethering DNA damage checkpoint mediator proteins topoisomerase IIbeta-binding protein 1 (TopBP1) and Claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1)Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication.Role for casein kinase 1 in the phosphorylation of Claspin on critical residues necessary for the activation of Chk1.Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts.SUMOylation of the C-terminal domain of DNA topoisomerase IIα regulates the centromeric localization of Claspin.The human Tim-Tipin complex interacts directly with DNA polymerase epsilon and stimulates its synthetic activity.Cdc7-dependent and -independent phosphorylation of Claspin in the induction of the DNA replication checkpoint DNA polymerase epsilon: a polymerase of unusual size (and complexity).The direct binding of Mrc1, a checkpoint mediator, to Mcm6, a replication helicase, is essential for the replication checkpoint against methyl methanesulfonate-induced stress.Molecular mechanisms of DNA replication checkpoint activation CRL2Lrr1 promotes unloading of the vertebrate replisome from chromatin during replication termination.A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function Mrc1/Claspin: a new role for regulation of origin firing.Fission yeast Swi1-Swi3 complex facilitates DNA binding of Mrc1.Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells Claspin and Chk1 regulate replication fork stability by different mechanisms.The Rad9-Hus1-Rad1 checkpoint clamp regulates interaction of TopBP1 with ATR.Cdc7 kinase mediates Claspin phosphorylation in DNA replication checkpoint.Function of the Plant DNA Polymerase Epsilon in Replicative Stress Sensing, a Genetic Analysis.Activation of CHEK1 at resected DNA DSBs Efficient expression and purification of human replication fork-stabilizing factor, Claspin, from mammalian cells: DNA-binding activity and novel protein interactions.USP29 controls the stability of checkpoint adaptor Claspin by deubiquitination.

P2860

Q24302160-9EA29635-E4CC-4227-8A61-BC11B0763576 Q24314027-AAD586E8-F49C-49EA-8FFA-909F924AC665 Q24315071-72A709C1-98D6-47C7-A023-D825DD119D9E Q24601538-7E8B7EB1-5410-46D8-85A3-D9BE4100733F Q24642626-75D31422-D5F3-42F8-97EA-913B633B931F Q24649012-DBF77CDD-2E6E-419F-ACF4-0DD86D83BBFE Q26822699-B58C828C-7C6E-4D02-B73A-110FCBEF0B18 Q28297227-3EF4AC3D-B942-4D20-99AA-10C469F43F3C Q33721233-58602C0F-6658-4FCD-9C14-545C5625BD02 Q33800164-6E0052A6-72ED-4C4F-B392-70AD63D58FE1 Q34134053-105ABFF2-1924-41BA-A6FA-966A3DFA7393 Q34148484-C47EBA3E-5981-43F8-B09C-B2E588A4D8BC Q34619662-94C93848-1C36-46F4-9975-5381B31928A4 Q34649104-C15208EE-E5BD-4CB2-951B-DD16066E61C1 Q35010875-EE42B351-78A2-492B-8837-0A76B7BB59D8 Q35047506-8F517EB5-5995-471C-8CE6-17E60A9A515A Q35160712-981EDDE9-CFF7-4D5E-86AB-974D1A1018C0 Q35989104-E02E874F-3033-4053-A517-CD842544E9C2 Q36186507-C75CAFCA-EF19-42A7-B005-972F16DB1D33 Q36812407-A3910F4B-3B93-4441-A24C-6F3761F923FA Q36923333-BC12E09B-1623-48BC-BE21-8803340191E0 Q36961060-AD409AE7-9909-4E62-8880-EA858F416BF3 Q37334042-8216814B-9F98-48DD-BD0B-73F021CCE484 Q37689837-6FFD3906-92F2-47AE-9222-4D69768FAA59 Q38943169-0329255E-4B90-43A8-A080-6B82F3CFF3E8 Q39142830-BFE71A48-407A-4828-8429-65CC1D4F968F Q39208248-261F9B66-6C09-40E6-A4F2-B3B29184533E Q41129648-C28125A2-61F2-4B21-8682-72A327BFF602 Q41850137-9B4F84F0-D8D1-440B-9202-72FE3D21BB86 Q42227954-CE036778-5ACA-49F0-BC80-F85EE1D57910 Q45936344-8D030348-4FB9-4E96-A76E-47735CBCAC08 Q46847087-10A34D85-047B-47B4-A592-1EE8920A835E Q47987433-2FF1125E-6073-4FFF-B11A-636D033FD0E6 Q50287358-28F3EF35-ACE5-49BA-9EC7-451E66E8BA87 Q52725097-AAC2A982-45EA-47BD-87E3-5D0FAA00BCA0 Q53062242-4194AECF-B338-429E-8439-2C9210079960

P2860

Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response.

http://www.wikidata.org/entity/Q34099551

description

2005 nî lūn-bûn

@nan

2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Roles of replication fork-inte ...... plication checkpoint response.

@ast

Roles of replication fork-inte ...... plication checkpoint response.

@en

Roles of replication fork-inte ...... plication checkpoint response.

@nl

type

label

Roles of replication fork-inte ...... plication checkpoint response.

@ast

Roles of replication fork-inte ...... plication checkpoint response.

@en

Roles of replication fork-inte ...... plication checkpoint response.

@nl

prefLabel

Roles of replication fork-inte ...... plication checkpoint response.

@ast

Roles of replication fork-inte ...... plication checkpoint response.

@en

Roles of replication fork-inte ...... plication checkpoint response.

@nl

P1433

Q34099551-1AF902E7-5ADA-4FCC-927D-754388A1959B

P1476

Q34099551-F6DB6F5B-B1C5-434C-88D7-EDE4B2895A0E

P2093

Q34099551-090548A0-5106-436F-97E3-DC0D4420F22B

Q34099551-27F8EE0F-8347-4DA1-BD3F-F38191040D41

Q34099551-3052D771-1D3E-431C-830F-83E5805322CC

Q34099551-307A31CB-5076-4B65-B1E6-7285AC1FE0FF

Q34099551-6D1BA437-F229-4F3C-A52F-4D9624D83CA4

P2860

Q34099551-058A5852-9B55-4F1F-A25F-305F23CB128C

Q34099551-0B5E70B2-24AB-45D5-92E6-31B528BF8C13

Q34099551-14B77149-7BA9-4661-B98B-EE797E47904D

Q34099551-17C50369-01FD-4FFD-92E2-53F86E61CC26

Q34099551-189AF2B4-4109-469D-9BF0-134C7147E689

Q34099551-1F230B24-79C0-4525-AB3D-26FC4537D12D

Q34099551-204ECE81-9258-4BA2-93C1-ED7BB4D78B04

Q34099551-267E4F72-FEE7-44D6-96EE-4516EC1742C7

Q34099551-2CCAE1F5-3664-407B-9A10-F7647E2A486C

Q34099551-2E4CC28D-5233-474E-B239-659488A1DE0B

P304

Q34099551-0650E8D7-2F79-4824-AE28-B065DF227577

P31

Q34099551-0A83DD20-9082-444D-A630-E9224496F3C8

P356

Q34099551-F03A6A28-9DB7-4388-83F2-72478A4457A7

P433

Q34099551-D2AEBEDE-C6CE-4A0B-B5A6-4E2DC0E1D961

P478

Q34099551-FD7AD986-CE94-4601-94BC-5AD9F95AE00F

P577

Q34099551-39A9DCF2-E3C8-4AF7-AA80-22672AC7B860

P698

Q34099551-82AAE124-B411-404B-8A47-B75563992402

P932

Q34099551-70267DD4-761D-410A-B446-32EE9C9140CD

P356

MBC.E05-07-0671

P1433

Molecular Biology of the Cell

P1476

Roles of replication fork-inte ...... plication checkpoint response.

@en

P2093

Andrej Shevchenko

http://www.w3.org/2001/XMLSchema#string

Anna Shevchenko

http://www.w3.org/2001/XMLSchema#string

Daniel A Gold

http://www.w3.org/2001/XMLSchema#string

Joon Lee

http://www.w3.org/2001/XMLSchema#string

William G Dunphy

http://www.w3.org/2001/XMLSchema#string

P2860

Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk.

Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

Replication protein A-mediated recruitment and activation of Rad17 complexes

Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

Mrc1 transduces signals of DNA replication stress to activate Rad53.

S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex.

Central role for cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extracts

Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1

P304

5269-5282

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1091/MBC.E05-07-0671

http://www.w3.org/2001/XMLSchema#string

P433

11

http://www.w3.org/2001/XMLSchema#string

P478

16

http://www.w3.org/2001/XMLSchema#string

P577

2005-09-07T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

16148040

http://www.w3.org/2001/XMLSchema#string

P932

1266425

http://www.w3.org/2001/XMLSchema#string