PDE7A is expressed in human B-lymphocytes and is up-regulated by elevation of intracellular cAMP.
about
Functional characterization of the human phosphodiesterase 7A1 promoterIloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungsPDE 7 inhibitors: new potential drugs for the therapy of spinal cord injuryConstitutive activation of Galphas within forebrain neurons causes deficits in sensorimotor gating because of PKA-dependent decreases in cAMP.Multiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7.New classes of PDE7 inhibitors identified by a fission yeast-based HTS.Ubiquitous expression of phosphodiesterase 7A in human proinflammatory and immune cells.Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes.Apoptosis as a tool for therapeutic agents in haematological diseases.PDE7 inhibitor TC3.6 ameliorates symptomatology in a model of primary progressive multiple sclerosisCyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies.Cyclic nucleotide phosphodiesterase profiling reveals increased expression of phosphodiesterase 7B in chronic lymphocytic leukemia.The role of cyclic nucleotide signaling pathways in cancer: targets for prevention and treatmentCyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments.Targeting cAMP in chronic lymphocytic leukemia: a pathway-dependent approach for the treatment of leukemia and lymphoma.Temporal and spatial regulation of cAMP signaling in disease: role of cyclic nucleotide phosphodiesterases.cAMP-specific phosphodiesterase inhibitors: promising drugs for inflammatory and neurological diseases.Phase II study of theophylline in chronic lymphocytic leukemia: a study of the Eastern Cooperative Oncology Group (E4998).Phosphodiesterase7 Inhibition Activates Adult Neurogenesis in Hippocampus and Subventricular Zone In Vitro and In Vivo.Identification and characterization of a potent and biologically-active PDE4/7 inhibitor via fission yeast-based assays.
P2860
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P2860
PDE7A is expressed in human B-lymphocytes and is up-regulated by elevation of intracellular cAMP.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
PDE7A is expressed in human B- ...... evation of intracellular cAMP.
@ast
PDE7A is expressed in human B- ...... evation of intracellular cAMP.
@en
PDE7A is expressed in human B- ...... evation of intracellular cAMP.
@nl
type
label
PDE7A is expressed in human B- ...... evation of intracellular cAMP.
@ast
PDE7A is expressed in human B- ...... evation of intracellular cAMP.
@en
PDE7A is expressed in human B- ...... evation of intracellular cAMP.
@nl
prefLabel
PDE7A is expressed in human B- ...... evation of intracellular cAMP.
@ast
PDE7A is expressed in human B- ...... evation of intracellular cAMP.
@en
PDE7A is expressed in human B- ...... evation of intracellular cAMP.
@nl
P2093
P1433
P1476
PDE7A is expressed in human B- ...... evation of intracellular cAMP.
@en
P2093
Adam Lerner
Carmen Hertel
Eunyi Moon
James Esselstyn
Richard Lee
Sharon Wolda
P304
P356
10.1016/S0898-6568(01)00250-9
P577
2002-03-01T00:00:00Z