Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease
about
Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body diseaseAlpha-synuclein and tau: teammates in neurodegeneration?Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-βDNA methylation of the MAPT gene in Parkinson's disease cohorts and modulation by vitamin E in vitroMotor and cognitive deficits in aged tau knockout mice in two background strains.Intranasal NAP (davunetide) decreases tau hyperphosphorylation and moderately improves behavioral deficits in mice overexpressing α-synuclein.A powerful yeast model to investigate the synergistic interaction of α-synuclein and tau in neurodegeneration.Tau reduction prevents disease in a mouse model of Dravet syndromeWhat we can learn from animal models about cerebral multi-morbidity.Tropism and Induction of Cytokines in Human Embryonic-Stem Cells-Derived Neural Progenitors upon Inoculation with Highly- Pathogenic Avian H5N1 Influenza VirusHumanized Tau Mice with Regionalized Amyloid Exhibit Behavioral Deficits but No Pathological Interaction.Lessons from tau-deficient miceNo Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin MiceEvolution of neurodegeneration.Absence of Tau triggers age-dependent sciatic nerve morphofunctional deficits and motor impairmentAge-appropriate cognition and subtle dopamine-independent motor deficits in aged tau knockout miceThe Effect of MSCs Derived from the Human Umbilical Cord Transduced by Fibroblast Growth Factor-20 on Parkinson's Disease.What Renders TAU ToxicHyperphosphorylated tau is implicated in acquired epilepsy and neuropsychiatric comorbidities.Interactions Between α-Synuclein and Tau Protein: Implications to Neurodegenerative Disorders.Interactions of pathological proteins in neurodegenerative diseases.Peripheral Elevation of a Klotho Fragment Enhances Brain Function and Resilience in Young, Aging, and α-Synuclein Transgenic Mice.Ironing out tau's role in parkinsonism.Axonal Degeneration in Tauopathies: Disease Relevance and Underlying Mechanisms.Tau Deficiency Down-Regulated Transcription Factor Orthodenticle Homeobox 2 Expression in the Dopaminergic Neurons in Ventral Tegmental Area and Caused No Obvious Motor Deficits in Mice.Lack of exacerbation of neurodegeneration in a double transgenic mouse model of mutant LRRK2 and tau.Battery of Behavioral Tests Assessing General Locomotion, Muscular Strength, and Coordination in Mice.Unilateral Botulinum Neurotoxin-A Injection into the Striatum of C57BL/6 Mice Leads to a Different Motor Behavior Compared with Rats
P2860
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P2860
Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease
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2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease
@ast
Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease
@en
Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease
@nl
type
label
Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease
@ast
Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease
@en
Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease
@nl
prefLabel
Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease
@ast
Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease
@en
Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease
@nl
P2093
P2860
P1433
P1476
Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease
@en
P2093
Akihiko Koyama
Lennart Mucke
Meaghan Morris
P2860
P304
P356
10.1371/JOURNAL.PONE.0029257
P407
P577
2011-12-19T00:00:00Z