about
Protein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestorEvolution of a novel subfamily of nuclear receptors with members that each contain two DNA binding domainsA novel inducible transactivation domain in the androgen receptor: implications for PRK in prostate cancerX-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.Direct channeling of retinoic acid between cellular retinoic acid-binding protein II and retinoic acid receptor sensitizes mammary carcinoma cells to retinoic acid-induced growth arrestRecurrent mutation in the first zinc finger of the orphan nuclear receptor NR2E3 causes autosomal dominant retinitis pigmentosaThe structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor gamma ligand-binding domain in the complex with two enantiomeric ligandsModulators of the structural dynamics of the retinoid X receptor to reveal receptor functionStructural and functional insights into the ligand-binding domain of a nonduplicated retinoid X nuclear receptor from the invertebrate chordate amphioxusStructural basis for the activation of PPARgamma by oxidized fatty acidsStructural Basis for Retinoic X Receptor Repression on the TetramerStructural Basis of Digoxin That Antagonizes ROR t Receptor Activity and Suppresses Th17 Cell Differentiation and Interleukin (IL)-17 ProductionStructural basis for differential recognition of brassinolide by its receptorsUnprecedented conformational flexibility revealed in the ligand-binding domains of the Bovicola ovis ecdysone receptor (EcR) and ultraspiracle (USP) subunitsThe amino acid residues asparagine 354 and isoleucine 372 of human farnesoid X receptor confer the receptor with high sensitivity to chenodeoxycholateDomains of ERRgamma that mediate homodimerization and interaction with factors stimulating DNA bindingEvidence for ligand-independent transcriptional activation of the human estrogen-related receptor alpha (ERRalpha): crystal structure of ERRalpha ligand binding domain in complex with peroxisome proliferator-activated receptor coactivator-1alphaMouse retinal dehydrogenase 4 (RALDH4), molecular cloning, cellular expression, and activity in 9-cis-retinoic acid biosynthesis in intact cellsThe molecular basis of conformational instability of the ecdysone receptor DNA binding domain studied by in silico and in vitro experimentsIdentification of Tetraazacyclic Compounds as Novel Potent Inhibitors Antagonizing RORγt Activity and Suppressing Th17 Cell DifferentiationWhat are nuclear receptor ligands?Cyclin H binding to the RARalpha activation function (AF)-2 domain directs phosphorylation of the AF-1 domain by cyclin-dependent kinase 7.PPARG: Gene Expression Regulation and Next-Generation Sequencing for Unsolved Issues.Structural basis for HNF-4alpha activation by ligand and coactivator binding.The X-ray structure of a hemipteran ecdysone receptor ligand-binding domain: comparison with a lepidopteran ecdysone receptor ligand-binding domain and implications for insecticide design.Agonist and antagonist binding to the nuclear vitamin D receptor: dynamics, mutation effects and functional implications.Fungi and animals may share a common ancestor to nuclear receptors.Phosphorylation by PKA potentiates retinoic acid receptor alpha activity by means of increasing interaction with and phosphorylation by cyclin H/cdk7.Thyroid hormone receptor mutations in cancer and resistance to thyroid hormone: perspective and prognosisUnliganded and hormone-bound glucocorticoid receptors interact with distinct hydrophobic sites in the Hsp90 C-terminal domain.Effects of Sulfonylureas on Peroxisome Proliferator-Activated Receptor γ Activity and on Glucose Uptake by Thiazolidinediones.Reporter Cell Lines for the Characterization of the Interactions between Human Nuclear Receptors and Endocrine Disruptors.Reporter cell lines to evaluate the selectivity of chemicals for human and zebrafish estrogen and peroxysome proliferator activated γ receptorsThe role of peroxisome proliferator-activated receptors in the esophageal, gastric, and colorectal cancerUsing nondenaturing mass spectrometry to detect fortuitous ligands in orphan nuclear receptors.The impact of aryl hydrocarbon receptor signaling on matrix metabolism: implications for development and disease.A conformational switch in the ligand-binding domain regulates the dependence of the glucocorticoid receptor on Hsp90.An F-domain introduced by alternative splicing regulates activity of the zebrafish thyroid hormone receptor alpha.Dynamic and combinatorial control of gene expression by nuclear retinoic acid receptors (RARs).
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Structural studies on nuclear receptors.
@ast
Structural studies on nuclear receptors.
@en
Structural studies on nuclear receptors.
@nl
type
label
Structural studies on nuclear receptors.
@ast
Structural studies on nuclear receptors.
@en
Structural studies on nuclear receptors.
@nl
prefLabel
Structural studies on nuclear receptors.
@ast
Structural studies on nuclear receptors.
@en
Structural studies on nuclear receptors.
@nl
P356
P1476
Structural studies on nuclear receptors
@en
P2093
P2888
P304
P356
10.1007/PL00000656
P577
2000-11-01T00:00:00Z