The putative ovarian tumour marker gene HE4 (WFDC2), is expressed in normal tissues and undergoes complex alternative splicing to yield multiple protein isoforms.
about
WFDC2 (HE4): a potential role in the innate immunity of the oral cavity and respiratory tract and the development of adenocarcinomas of the lungHuman epididymis protein-4 (HE-4): a novel cross-class protease inhibitorVoxelwise genome-wide association study (vGWAS)HE4 a novel tumour marker for ovarian cancer: comparison with CA 125 and ROMA algorithm in patients with gynaecological diseasesThe evolution of a genetic locus encoding small serine proteinase inhibitorsComparison in gene expression of secretory human endometrium using laser microdissectionSerum HE4, CA125, YKL-40, bcl-2, cathepsin-L and prediction optimal debulking surgery, response to chemotherapy in ovarian cancer.Comprehensive analysis of HE4 expression in normal and malignant human tissues.A molecular signature of gastric metaplasia arising in response to acute parietal cell lossOvarian cancer biomarkers for molecular biosensors and translational medicine.Physiologic variations of serum tumor markers in gynecological malignancies during pregnancy: a systematic review.HE4 in the differential diagnosis of a pelvic mass: a case report.HE4 as a biomarker for ovarian and endometrial cancer management.HE4 and CA125 as a diagnostic test in ovarian cancer: prospective validation of the Risk of Ovarian Malignancy Algorithm.An extensive targeted proteomic analysis of disease-related protein biomarkers in urine from healthy donors.Co-expression of Lewis y antigen with human epididymis protein 4 in ovarian epithelial carcinomaNanoparticle-delivered suicide gene therapy effectively reduces ovarian tumor burden in miceDiagnostic and prognostic impact of serum HE4 detection in endometrial carcinoma patientsfTwo novel biomarkers, mesothelin and HE4, for diagnosis of ovarian carcinoma.Evaluation of human epididymis protein 4 (HE4) and Risk of Ovarian Malignancy Algorithm (ROMA) as diagnostic tools of type I and type II epithelial ovarian cancer in Japanese womenParacrine SLPI secretion upregulates MMP-9 transcription and secretion in ovarian cancer cellsSerum HE4 is more suitable as a biomarker than CA125 in Chinese women with benign gynecologic disordersIdentification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosisHuman epididymis protein 4 is up-regulated in gastric and pancreatic adenocarcinomasHE4 (WFDC2) Promotes Tumor Growth in Endometrial Cancer Cell LinesHE4 promotes collateral resistance to cisplatin and paclitaxel in ovarian cancer cellsClinical efficacy of serum human epididymis protein 4 as a diagnostic biomarker of ovarian cancer: A pilot study.HE4 transcription- and splice variants-specific expression in endometrial cancer and correlation with patient survival.HE4 (WFDC2) gene overexpression promotes ovarian tumor growthHE4 tumor marker concentration in neoplastic peritoneal effusion and in peritoneal fluid associated with benign gynecological diseasesElevated serum concentrations of HE4 as a novel biomarker of disease severity and renal fibrosis in kidney disease.Towards defining the complement of mammalian WFDC-domain-containing proteins.Immunotherapy of prostate cancer: identification of new treatments and targets for therapy, and role of WAP domain-containing proteins.From bench to bedside: discovery of ovarian cancer biomarkers using high-throughput technologies in the past decade.HE4-test of urine and body fluids for diagnosis of gynecologic cancer.Physiopathological factors affecting the diagnostic value of serum HE4-test for gynecologic malignancies.The role of HE4 in ovarian cancer: inhibiting tumour cell proliferation and metastasis.Splice variant HE4-V3 expression is associated with favorable prognosis in pulmonary adenocarcinoma.Serum level of HE4 is closely associated with pulmonary adenocarcinoma progression.Composition of the bovine uterine proteome is associated with stage of cycle and concentration of systemic progesterone.
P2860
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P2860
The putative ovarian tumour marker gene HE4 (WFDC2), is expressed in normal tissues and undergoes complex alternative splicing to yield multiple protein isoforms.
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The putative ovarian tumour ma ...... eld multiple protein isoforms.
@ast
The putative ovarian tumour ma ...... eld multiple protein isoforms.
@en
The putative ovarian tumour ma ...... eld multiple protein isoforms.
@nl
type
label
The putative ovarian tumour ma ...... eld multiple protein isoforms.
@ast
The putative ovarian tumour ma ...... eld multiple protein isoforms.
@en
The putative ovarian tumour ma ...... eld multiple protein isoforms.
@nl
prefLabel
The putative ovarian tumour ma ...... eld multiple protein isoforms.
@ast
The putative ovarian tumour ma ...... eld multiple protein isoforms.
@en
The putative ovarian tumour ma ...... eld multiple protein isoforms.
@nl
P2093
P2860
P356
P1433
P1476
The putative ovarian tumour ma ...... eld multiple protein isoforms.
@en
P2093
Colin D Bingle
Lynne Bingle
Vanessa Singleton
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205363
P407
P577
2002-04-01T00:00:00Z
P5875
P6179
1010261806