Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility.
about
Neurosteroids and GABA(A) Receptor Interactions: A Focus on StressAnticonvulsant activity of androsterone and etiocholanolone.The role of sex steroids in catamenial epilepsy and premenstrual dysphoric disorder: implications for diagnosis and treatmentAnticonvulsant potencies of the enantiomers of the neurosteroids androsterone and etiocholanolone exceed those of the natural formsThe testosterone-derived neurosteroid androstanediol is a positive allosteric modulator of GABAA receptorsRole of neurosteroids in the anticonvulsant activity of midazolamNeurosteroids: endogenous role in the human brain and therapeutic potentialsDiverse mechanisms of antiepileptic drugs in the development pipelineCatamenial Epilepsy: Discovery of an Extrasynaptic Molecular Mechanism for Targeted TherapyGABA Signaling and Neuroactive Steroids in Adrenal Medullary Chromaffin CellsStress, seizures, and hypothalamic-pituitary-adrenal axis targets for the treatment of epilepsyNeurosteroids and their role in sex-specific epilepsiesMechanisms of Action of Antiseizure Drugs and the Ketogenic DietBlunted neuroactive steroid and HPA axis responses to stress are associated with reduced sleep quality and negative affect in pregnancy: a pilot studyApplications of schedule-induced polydipsia in rodents for the study of an excessive ethanol intake phenotype.The impact of gonadectomy and adrenalectomy on acute withdrawal severity in male and female C57BL/6J and DBA/2J mice following a single high dose of ethanol.Replacement with GABAergic steroid precursors restores the acute ethanol withdrawal profile in adrenalectomy/gonadectomy mice.Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors.Stress-induced plasticity of GABAergic inhibition.Ganaxolone suppression of behavioral and electrographic seizures in the mouse amygdala kindling modelNeurosteroids and GABAergic signaling in health and diseasePrenatal and perinatal risk factors in a twin study of autism spectrum disorders.Genetic analysis of the neurosteroid deoxycorticosterone and its relation to alcohol phenotypes: identification of QTLs and downstream gene regulation.Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies.Neurosteroids and epilepsy.Neurosteroid withdrawal regulates GABA-A receptor α4-subunit expression and seizure susceptibility by activation of progesterone receptor-independent early growth response factor-3 pathwayPerimenstrual-like hormonal regulation of extrasynaptic δ-containing GABAA receptors mediating tonic inhibition and neurosteroid sensitivity.11-Deoxycortisol impedes GABAergic neurotransmission and induces drug-resistant status epilepticus in mice.11β-Hydroxylase inhibitors protect against seizures in mice by increasing endogenous neurosteroid synthesis.Reduction of circulating and selective limbic brain levels of (3α,5α)-3-hydroxy-pregnan-20-one (3α,5α-THP) following forced swim stress in C57BL/6J miceHypothalamic-pituitary-adrenal axis modulation of GABAergic neuroactive steroids influences ethanol sensitivity and drinking behaviorAspects of the homeostaic plasticity of GABAA receptor-mediated inhibition.Neurosteroids and GABA-A Receptor Function.Role of anticonvulsant and antiepileptogenic neurosteroids in the pathophysiology and treatment of epilepsy.Inhibition by alpha-tetrahydrodeoxycorticosterone (THDOC) of pre-sympathetic parvocellular neurones in the paraventricular nucleus of rat hypothalamus.Steroid hormone fluctuations and GABA(A)R plasticity.Neuroendocrine aspects of catamenial epilepsyFinasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis.Differential hypothalamic-pituitary-adrenal activation of the neuroactive steroids pregnenolone sulfate and deoxycorticosterone in healthy controls and alcohol-dependent subjectsMass spectrometric assay and physiological-pharmacological activity of androgenic neurosteroids
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P2860
Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA
@nl
Stress-induced deoxycorticoste ...... on and seizure susceptibility.
@ast
Stress-induced deoxycorticoste ...... on and seizure susceptibility.
@en
type
label
Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA
@nl
Stress-induced deoxycorticoste ...... on and seizure susceptibility.
@ast
Stress-induced deoxycorticoste ...... on and seizure susceptibility.
@en
prefLabel
Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA
@nl
Stress-induced deoxycorticoste ...... on and seizure susceptibility.
@ast
Stress-induced deoxycorticoste ...... on and seizure susceptibility.
@en
P1476
Stress-induced deoxycorticoste ...... ion and seizure susceptibility
@en
P2093
Doodipala S Reddy
Michael A Rogawski
P304
P356
10.1523/JNEUROSCI.22-09-03795.2002
P407
P577
2002-05-01T00:00:00Z