Activation of the farnesoid X receptor provides protection against acetaminophen-induced hepatic toxicity.
about
FXR signaling in the enterohepatic systemNuclear Receptors as Therapeutic Targets in Liver Disease: Are We There Yet?MAFG is a transcriptional repressor of bile acid synthesis and metabolismTrimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulationActivation of Sirt1/FXR Signaling Pathway Attenuates Triptolide-Induced Hepatotoxicity in Rats.Longevity is impacted by growth hormone action during early postnatal periodThe extended TILAR approach: a novel tool for dynamic modeling of the transcription factor network regulating the adaption to in vitro cultivation of murine hepatocytes.Chronic activation of FXR in transgenic mice caused perinatal toxicity and sensitized mice to cholesterol toxicity.Activation of liver X receptor increases acetaminophen clearance and prevents its toxicity in mice.Differential Fmo3 gene expression in various liver injury models involving hepatic oxidative stress in miceGenomic analysis of hepatic farnesoid X receptor binding sites reveals altered binding in obesity and direct gene repression by farnesoid X receptor in mice.Farnesoid X receptor activation promotes cell proliferation via PDK4-controlled metabolic reprogramming.Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR.Pleiotropic roles of bile acids in metabolism.Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptorMetabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosis.Regulation of human class I alcohol dehydrogenases by bile acids.Nuclear receptor control of enterohepatic circulation.AMPK activation by liquiritigenin inhibited oxidative hepatic injury and mitochondrial dysfunction induced by nutrition deprivation as mediated with induction of farnesoid X receptor.MicroRNA-144 regulates hepatic ATP binding cassette transporter A1 and plasma high-density lipoprotein after activation of the nuclear receptor farnesoid X receptor.Role of bile acids in liver injury and regeneration following acetaminophen overdose.Bile acids regulate cysteine catabolism and glutathione regeneration to modulate hepatic sensitivity to oxidative injury.Ameliorative effect of naringin in acetaminophen-induced hepatic and renal toxicity in laboratory rats: role of FXR and KIM-1.Effect of developmental NMDAR antagonism with CGP 39551 on aspartame-induced hypothalamic and adrenal gene expression.FXR deletion in hepatocytes does not affect the severity of alcoholic liver disease in mice
P2860
Q27014753-50B5935D-C3AC-41F5-971A-55AA91E5F587Q28066233-01A34820-850D-4557-B154-D96A3BB70D9AQ28256483-EA71DBDB-79F8-424C-AD3F-4BBC888813E0Q28283087-E4B074BA-BD6C-4AD8-BDF5-9364577A5337Q33650563-EC9175D7-2B0D-4BAF-98B6-7BAF202495A1Q33915561-A2BE87B9-33A0-46BE-8D32-F7448B2E2893Q34494671-1D422FB9-F12F-41A0-AF25-38D0D0AB5809Q35441714-37680BB9-697A-4486-B630-2778E4BF2A8DQ35592953-52CC2881-8A2C-43CD-A432-FF273A736FC0Q35596350-27245BA1-FAB5-4C1C-9FA5-026D3A240538Q35931282-ECE5A3AD-6A72-45E8-BCEE-FC889E2D2DF7Q36427805-9AA0634F-E7FA-4A9C-A2E9-57126DABA76FQ36683297-64DDF9F9-870F-4E81-A3AA-5DCDB13913EBQ36843966-528AD8FF-4C45-4C9E-8B60-E3685D732FC2Q36972583-349D43CD-78B0-4DD4-87AD-FBCA979979C0Q37004604-A4892CD5-262B-4C43-99E3-49E416A42686Q37076509-785EBF87-59A6-4512-AD6B-E9E244F54617Q38110503-896E8B1B-068A-4E90-8EEC-8EACDF5829B1Q38813580-754B2DD3-49F3-45F9-A4EE-E97214FEBDCDQ38898464-C608CFC8-163F-40C6-833F-C283C7AD7AEBQ42119327-6E2D5D5E-41DC-4374-851C-BED6531C3692Q52579660-8DFF5859-A353-4697-A43A-F333799DB8BCQ52876599-90218910-DB4D-4248-A3F3-CB90D061C8AAQ55239097-DACFFB70-94CE-446D-B470-6BCDF4B738DAQ57106885-E7A4111F-C31A-4035-AAD2-3D5E07B5CE07
P2860
Activation of the farnesoid X receptor provides protection against acetaminophen-induced hepatic toxicity.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Activation of the farnesoid X ...... phen-induced hepatic toxicity.
@ast
Activation of the farnesoid X ...... phen-induced hepatic toxicity.
@en
Activation of the farnesoid X ...... phen-induced hepatic toxicity.
@nl
type
label
Activation of the farnesoid X ...... phen-induced hepatic toxicity.
@ast
Activation of the farnesoid X ...... phen-induced hepatic toxicity.
@en
Activation of the farnesoid X ...... phen-induced hepatic toxicity.
@nl
prefLabel
Activation of the farnesoid X ...... phen-induced hepatic toxicity.
@ast
Activation of the farnesoid X ...... phen-induced hepatic toxicity.
@en
Activation of the farnesoid X ...... phen-induced hepatic toxicity.
@nl
P2093
P2860
P356
P1476
Activation of the farnesoid X ...... phen-induced hepatic toxicity.
@en
P2093
Florence Ying Lee
Hansook Kim Chong
Peter A Edwards
Stacey A Jones
Thomas Quad de Aguiar Vallim
Timothy F Osborne
Yanqiao Zhang
Yaping Liu
P2860
P304
P356
10.1210/ME.2010-0117
P577
2010-06-23T00:00:00Z