USE1 is a bispecific conjugating enzyme for ubiquitin and FAT10, which FAT10ylates itself in cis.
about
Investigations into the auto-FAT10ylation of the bispecific E2 conjugating enzyme UBA6-specific E2 enzyme 1E2 enzymes: more than just middle menModification by ubiquitin-like proteins: significance in apoptosis and autophagy pathwaysAltered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system.ELK1 transcription factor linked to dysregulated striatal mu opioid receptor signaling network and OPRM1 polymorphism in human heroin abusers.The inherited blindness protein AIPL1 regulates the ubiquitin-like FAT10 pathwayConjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation.Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins.Mechanistic studies on activation of ubiquitin and di-ubiquitin-like protein, FAT10, by ubiquitin-like modifier activating enzyme 6, Uba6Silibinin down-regulates FAT10 and modulate TNF-α/IFN-γ-induced chromosomal instability and apoptosis sensitivity.Profiling of ubiquitin-like modifications reveals features of mitotic control.Orthogonal ubiquitin transfer identifies ubiquitination substrates under differential control by the two ubiquitin activating enzymes.Extended lifespan and reduced adiposity in mice lacking the FAT10 gene.HIV-1, ubiquitin and ubiquitin-like proteins: the dialectic interactions of a virus with a sophisticated network of post-translational modifications.Association of Uba6-Specific-E2 (USE1) With Lung Tumorigenesis.Ubiquitin-like protein MNSFβ noncovalently binds to molecular chaperone HSPA8 and regulates osteoclastogenesis.FAT10 Is Critical in Influenza A Virus Replication by Inhibiting Type I IFN.FAT10, an ubiquitin-like protein, confers malignant properties in non-tumorigenic and tumorigenic cells.Inhibition of NEDD8 and FAT10 ligase activities through the degrading enzyme NEDD8 ultimate buster 1: A potential anticancer approach.Ubiquitin-like Protein Conjugation: Structures, Chemistry, and Mechanism.Structure of UBE2Z Enzyme Provides Functional Insight into Specificity in the FAT10 Protein Conjugation MachineryThe FAT10- and ubiquitin-dependent degradation machineries exhibit common and distinct requirements for MHC class I antigen presentation.Performance of ZDOCK and IRAD in CAPRI rounds 28-34.Newly translated proteins are substrates for ubiquitin, ISG15, and FAT10.Preclinical comparison of proteasome and ubiquitin E1 enzyme inhibitors in cutaneous squamous cell carcinoma: the identification of mechanisms of differential sensitivity.The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation
P2860
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P2860
USE1 is a bispecific conjugating enzyme for ubiquitin and FAT10, which FAT10ylates itself in cis.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
USE1 is a bispecific conjugati ...... ich FAT10ylates itself in cis.
@ast
USE1 is a bispecific conjugati ...... ich FAT10ylates itself in cis.
@en
USE1 is a bispecific conjugati ...... ich FAT10ylates itself in cis.
@nl
type
label
USE1 is a bispecific conjugati ...... ich FAT10ylates itself in cis.
@ast
USE1 is a bispecific conjugati ...... ich FAT10ylates itself in cis.
@en
USE1 is a bispecific conjugati ...... ich FAT10ylates itself in cis.
@nl
prefLabel
USE1 is a bispecific conjugati ...... ich FAT10ylates itself in cis.
@ast
USE1 is a bispecific conjugati ...... ich FAT10ylates itself in cis.
@en
USE1 is a bispecific conjugati ...... ich FAT10ylates itself in cis.
@nl
P2093
P356
P1476
USE1 is a bispecific conjugati ...... ich FAT10ylates itself in cis.
@en
P2093
Annette Aichem
Birte Kalveram
Christiane Pelzer
Gunter Schmidtke
Paul W Sheppard
Sebastian Lukasiak
P2888
P356
10.1038/NCOMMS1012
P407
P577
2010-05-04T00:00:00Z
P5875
P6179
1011547098