Unique assignment of inter-subunit association in GABA(A) alpha 1 beta 3 gamma 2 receptors determined by molecular modeling.
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Marine Toxins Targeting Ion ChannelsMechanisms of channel gating of the ligand-gated ion channel superfamily inferred from protein structure.The Molecular Mechanisms of Anesthetic Action: Updates and Cutting Edge Developments from the Field of Molecular Modeling.New insights into the GABA(A) receptor structure and orthosteric ligand binding: receptor modeling guided by experimental data.Homology model of the GABAA receptor examined using Brownian dynamicsDesign, synthesis, and subtype selectivity of 3,6-disubstituted β-carbolines at Bz/GABA(A)ergic receptors. SAR and studies directed toward agents for treatment of alcohol abuse.Binding interactions of antagonists with 5-hydroxytryptamine3A receptor models.GABA(A) receptor transmembrane amino acids are critical for alcohol action: disulfide cross-linking and alkyl methanethiosulfonate labeling reveal relative location of binding sitesCrystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors.The TM2 6' position of GABA(A) receptors mediates alcohol inhibitionRoles for loop 2 residues of alpha1 glycine receptors in agonist activation.Assessment of homology templates and an anesthetic binding site within the γ-aminobutyric acid receptor.Teaching an old GABA receptor new tricks.Probing the orthosteric binding site of GABAA receptors with heterocyclic GABA carboxylic acid bioisosteres.Rational design of alpha-conotoxin analogues targeting alpha7 nicotinic acetylcholine receptors: improved antagonistic activity by incorporation of proline derivatives.Serine 171, a conserved residue in the gamma-aminobutyric acid type A (GABAA) receptor gamma2 subunit, mediates subunit interaction and cell surface localization.A novel hyperekplexia-causing mutation in the pre-transmembrane segment 1 of the human glycine receptor alpha1 subunit reduces membrane expression and impairs gating by agonists.A novel pharmatope tag inserted into the beta4 subunit confers allosteric modulation to neuronal nicotinic receptors.Evidence that ethanol acts on a target in Loop 2 of the extracellular domain of alpha1 glycine receptors.
P2860
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P2860
Unique assignment of inter-subunit association in GABA(A) alpha 1 beta 3 gamma 2 receptors determined by molecular modeling.
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Unique assignment of inter-subunit association in GABA
@nl
Unique assignment of inter-sub ...... ermined by molecular modeling.
@ast
Unique assignment of inter-sub ...... ermined by molecular modeling.
@en
type
label
Unique assignment of inter-subunit association in GABA
@nl
Unique assignment of inter-sub ...... ermined by molecular modeling.
@ast
Unique assignment of inter-sub ...... ermined by molecular modeling.
@en
prefLabel
Unique assignment of inter-subunit association in GABA
@nl
Unique assignment of inter-sub ...... ermined by molecular modeling.
@ast
Unique assignment of inter-sub ...... ermined by molecular modeling.
@en
P1476
Unique assignment of inter-sub ...... ermined by molecular modeling.
@en
P2093
James Trudell
P356
10.1016/S0005-2736(02)00512-6
P407
P577
2002-09-01T00:00:00Z