Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes.
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Structure, mechanism and regulation of pyruvate carboxylaseEnhanced rat beta-cell proliferation in 60% pancreatectomized islets by increased glucose metabolic flux through pyruvate carboxylase pathwayA feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis.Dissociation of lipotoxicity and glucotoxicity in a mouse model of obesity associated diabetes: role of forkhead box O1 (FOXO1) in glucose-induced beta cell failure.Gene expression profiling in the type 1 diabetes rat diaphragm.Diabetic beta-cells can achieve self-protection against oxidative stress through an adaptive up-regulation of their antioxidant defenses.Plasma heme oxygenase-1 concentration is elevated in individuals with type 2 diabetes mellitus.Moving on from GWAS: functional studies on the G6PC2 gene implicated in the regulation of fasting blood glucose.Roux-en-Y gastric bypass promotes expression of PDX-1 and regeneration of beta-cells in Goto-Kakizaki rats.Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes.Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult ratsReversible changes in pancreatic islet structure and function produced by elevated blood glucose.Possible role of interleukin-1β in type 2 diabetes onset and implications for anti-inflammatory therapy strategies.Maternal serum heme-oxygenase-1 (HO-1) concentrations in early pregnancy and subsequent risk of gestational diabetes mellitusGlucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice.Islet beta cell failure in type 2 diabetesDifferences between human and rodent pancreatic islets: low pyruvate carboxylase, atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets.Type 1, type 1.5, and type 2 diabetes: NOD the diabetes we thought it wasSustained NF-κB activation and inhibition in β-cells have minimal effects on function and islet transplant outcomesInhibition of Id1 augments insulin secretion and protects against high-fat diet-induced glucose intolerance.LKB1 and AMPK differentially regulate pancreatic β-cell identity.Nutrient induced type 2 and chemical induced type 1 experimental diabetes differently modulate gastric GLP-1 receptor expression.Novel stable isotope analyses demonstrate significant rates of glucose cycling in mouse pancreatic islets.The Fas pathway is involved in pancreatic beta cell secretory function.Monosodium Glutamate Dietary Consumption Decreases Pancreatic β-Cell Mass in Adult Wistar Rats.Beta-cell mass plasticity in type 2 diabetes.The isolated pancreatic islet as a micro-organ and its transplantation to cure diabetes: celebrating the legacy of Paul Lacy.A simple matter of life and death-the trials of postnatal Beta-cell mass regulationChange in Serum Bilirubin Level as a Predictor of Incident Metabolic SyndromeBeyond the brain: disrupted in schizophrenia 1 regulates pancreatic β-cell function via glycogen synthase kinase-3β.A Mathematical Model of the Pathogenesis, Prevention, and Reversal of Type 2 DiabetesIslet β cell mass in diabetes and how it relates to function, birth, and death.PANIC-ATTAC: a mouse model for inducible and reversible beta-cell ablation.Overexpression of inducible cyclic AMP early repressor inhibits transactivation of genes and cell proliferation in pancreatic beta cells.Liraglutide prevents fast weight gain and β-cell dysfunction in male catch-up growth ratsPDX1 in ducts is not required for postnatal formation of β-cells but is necessary for their subsequent maturation.Tissue-specific regulation and expression of heat shock proteins in type 2 diabetic monkeys.VHL-mediated disruption of Sox9 activity compromises β-cell identity and results in diabetes mellitus.Effect of oxidative stress on heme oxygenase-1 expression in patients with gestational diabetes mellitus.Glucagon gene expression in the endocrine pancreas: the role of the transcription factor Pax6 in α-cell differentiation, glucagon biosynthesis and secretion.
P2860
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P2860
Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Critical reduction in beta-cel ...... nce or decompensated diabetes.
@ast
Critical reduction in beta-cel ...... nce or decompensated diabetes.
@en
Critical reduction in beta-cel ...... nce or decompensated diabetes.
@nl
type
label
Critical reduction in beta-cel ...... nce or decompensated diabetes.
@ast
Critical reduction in beta-cel ...... nce or decompensated diabetes.
@en
Critical reduction in beta-cel ...... nce or decompensated diabetes.
@nl
prefLabel
Critical reduction in beta-cel ...... nce or decompensated diabetes.
@ast
Critical reduction in beta-cel ...... nce or decompensated diabetes.
@en
Critical reduction in beta-cel ...... nce or decompensated diabetes.
@nl
P2093
P356
P1476
Critical reduction in beta-cel ...... nce or decompensated diabetes.
@en
P2093
D Ross Laybutt
Gordon C Weir
Mariela Glandt
Nitin Trivedi
Susan Bonner-Weir
Yu Bai Ahn
P304
P356
10.1074/JBC.M210581200
P407
P577
2002-11-15T00:00:00Z