Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice.
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Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient miceThe Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of LangerhansAdenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replicationIslet biology, the CDKN2A/B locus and type 2 diabetes risk.Adult tissue sources for new β cells.Pancreatic β-cell proliferation in obesity.Human β-cell regeneration: progress, hurdles, and controversy.Betatrophin versus bitter-trophin and the elephant in the room: time for a new normal in β-cell regeneration research.Human islet preparations distributed for research exhibit a variety of insulin-secretory profiles.Regulated and reversible induction of adult human β-cell replication.Free fatty acids block glucose-induced β-cell proliferation in mice by inducing cell cycle inhibitors p16 and p18Betatrophin in Diabetes Mellitus: the Epidemiological Evidence in Humans.Age-related loss of brain volume and T2 relaxation time in youth with type 1 diabetes.Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD-scid IL-2rg(null) RIP-DTR mice engrafted with human islets.The double trouble of metabolic diseases: the diabetes-cancer link.Chemical methods to induce Beta-cell proliferation.ChREBP mediates glucose-stimulated pancreatic β-cell proliferation.Augmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human β-Cells.Pancreatic beta cells in very old mice retain capacity for compensatory proliferation.MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity.Induction of the ChREBPβ Isoform Is Essential for Glucose-Stimulated β-Cell ProliferationAdaptive changes of human islets to an obesogenic environment in the mouse.FoxO1 Plays an Important Role in Regulating β-Cell Compensation for Insulin Resistance in Male Mice.Islet β cell mass in diabetes and how it relates to function, birth, and death.Inhibition of TGF-β Signaling Promotes Human Pancreatic β-Cell Replication.PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2Trimeprazine increases IRS2 in human islets and promotes pancreatic β cell growth and function in miceStress-impaired transcription factor expression and insulin secretion in transplanted human islets.How to make a functional β-cellEarly and Late G1/S Cyclins and Cdks Act Complementarily to Enhance Authentic Human β-Cell Proliferation and Expansion.Inhibition of DYRK1A Stimulates Human β-Cell ProliferationHuman pancreatic β-cell G1/S molecule cell cycle atlas.Npas4 is a novel activity-regulated cytoprotective factor in pancreatic β-cells.Adaptive β-cell proliferation increases early in high-fat feeding in mice, concurrent with metabolic changes, with induction of islet cyclin D2 expression.Activation of GPR119 Stimulates Human β-Cell Replication and Neogenesis in Humanized Mice with Functional Human IsletsStreptozotocin is equally diabetogenic whether administered to fed or fasted micePhospho-BAD BH3 mimicry protects β cells and restores functional β cell mass in diabetes.Improved function and proliferation of adult human beta cells engrafted in diabetic immunodeficient NOD-scid IL2rγ(null) mice treated with alogliptin.Targeting the cell cycle inhibitor p57Kip2 promotes adult human β cell replication.Mild hyperglycemia triggered islet function recovery in streptozotocin-induced insulin-deficient diabetic rats.
P2860
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P2860
Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Glucose stimulates human beta ...... immunodeficiency (SCID) mice.
@ast
Glucose stimulates human beta ...... immunodeficiency (SCID) mice.
@en
Glucose stimulates human beta ...... vere combined immunodeficiency
@nl
type
label
Glucose stimulates human beta ...... immunodeficiency (SCID) mice.
@ast
Glucose stimulates human beta ...... immunodeficiency (SCID) mice.
@en
Glucose stimulates human beta ...... vere combined immunodeficiency
@nl
prefLabel
Glucose stimulates human beta ...... immunodeficiency (SCID) mice.
@ast
Glucose stimulates human beta ...... immunodeficiency (SCID) mice.
@en
Glucose stimulates human beta ...... vere combined immunodeficiency
@nl
P2093
P2860
P1433
P1476
Glucose stimulates human beta ...... immunodeficiency (SCID) mice.
@en
P2093
A F Stewart
A Garcia-Ocaña
C P O'Donnell
D A Hollern
H E Levitt
J L Pascoe
L C Alonso
L C Romano
P2860
P2888
P304
P356
10.1007/S00125-010-1919-1
P577
2010-10-09T00:00:00Z
P5875
P6179
1021935693