Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
about
Electron Transport Disturbances and Neurodegeneration: From Albert Szent-Györgyi's Concept (Szeged) till Novel Approaches to Boost Mitochondrial BioenergeticsMitochondrial morphology-emerging role in bioenergeticsPGC-1α, mitochondrial dysfunction, and Huntington's diseaseAfter the banquet: mitochondrial biogenesis, mitophagy, and cell survivalDisruption of SUMO-specific protease 2 induces mitochondria mediated neurodegenerationMitochondrial functional state impacts spontaneous neocortical activity and resting state FMRISignal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fissionDynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseasesShaping the role of mitochondria in the pathogenesis of Huntington's diseaseMitochondrial dysfunction in neurodegenerative diseasesMetabolism in HD: still a relevant mechanism?Inhibition of mitochondrial protein import by mutant huntingtinOxygen consumption deficit in Huntington disease mouse brain under metabolic stressBax interacting factor-1 promotes survival and mitochondrial elongation in neuronsLongitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington's disease monkeys.PGC-1α overexpression exacerbates β-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease.DRP1 inhibition rescues retinal ganglion cells and their axons by preserving mitochondrial integrity in a mouse model of glaucoma.Comparison of Sirtuin 3 Levels in ALS and Huntington's Disease-Differential Effects in Human Tissue Samples vs. Transgenic Mouse Models.Abnormalities of Mitochondrial Dynamics in Neurodegenerative Diseases.D-β-hydroxybutyrate is protective in mouse models of Huntington's disease.Increased mitochondrial fission and neuronal dysfunction in Huntington's disease: implications for molecular inhibitors of excessive mitochondrial fissionDeceleration of fusion-fission cycles improves mitochondrial quality control during aging.PGC-1α provides a transcriptional framework for synchronous neurotransmitter release from parvalbumin-positive interneurons.Developmental alterations in motor coordination and medium spiny neuron markers in mice lacking pgc-1αTherapeutic approaches to preventing cell death in Huntington diseaseAbnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.Metabolic states following accumulation of intracellular aggregates: implications for neurodegenerative diseases.Autophagy-mediated turnover of dynamin-related protein 1.Development of an ELISA assay for the quantification of soluble huntingtin in human blood cells.Truncated peroxisome proliferator-activated receptor-γ coactivator 1α splice variant is severely altered in Huntington's diseaseMutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's diseaseMutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease.Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's diseaseEvidence for behavioral benefits of early dietary supplementation with CoEnzymeQ10 in a slowly progressing mouse model of Huntington's disease.Mitochondria: the next (neurode)generationmiR-196a Ameliorates Cytotoxicity and Cellular Phenotype in Transgenic Huntington's Disease Monkey Neural CellsPolyglutamine Tract Expansion Increases S-Nitrosylation of Huntingtin and Ataxin-1.Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease.PINK1-induced mitophagy promotes neuroprotection in Huntington's diseaseTransducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease.
P2860
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P2860
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
@ast
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
@en
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
@nl
type
label
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
@ast
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
@en
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
@nl
prefLabel
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
@ast
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
@en
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
@nl
P2093
P2860
P356
P1476
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
@en
P2093
Christina K Edgerly
Jennifer P Moody
Karen Smith
Kerry Cormier
M Flint Beal
Olivia L Bordiuk
P2860
P304
P356
10.1093/HMG/DDQ306
P577
2010-07-21T00:00:00Z