about
A simple negative interaction in the positive transcriptional feedback of a single gene is sufficient to produce reliable oscillationsEntrainment to periodic initiation and transition rates in a computational model for gene translationExcitability in the p53 network mediates robust signaling with tunable activation thresholds in single cellsSynthetic biology: integrated gene circuitsAdaptation for protein synthesis efficiency in a naturally occurring self-regulating operonMechanisms that enhance sustainability of p53 pulsesp53 Pulses Diversify Target Gene Expression Dynamics in an mRNA Half-Life-Dependent Manner and Delineate Co-regulated Target Gene Subnetworks.Mammalian synthetic biology for studying the cell.Emerging biomedical applications of synthetic biology.How cells process information: quantification of spatiotemporal signaling dynamics.Systems biology of cellular rhythms.Engineered genetic information processing circuits.Building robust functionality in synthetic circuits using engineered feedback regulation.Mathematical modeling for novel cancer drug discovery and development.Design principles for robust oscillatory behavior.Modeling of hysteresis in gene regulatory networks.Systems and synthetic biology approaches in understanding biological oscillators.Recent progress and open challenges in modeling p53 dynamics in single cells.Physical approaches to the dynamics of genetic circuits: a tutorialBirhythmicity and Hard Excitation from Coupled Synthetic Feedback Loops
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A synthetic-natural hybrid oscillator in human cells
@ast
A synthetic-natural hybrid oscillator in human cells
@en
A synthetic-natural hybrid oscillator in human cells
@nl
type
label
A synthetic-natural hybrid oscillator in human cells
@ast
A synthetic-natural hybrid oscillator in human cells
@en
A synthetic-natural hybrid oscillator in human cells
@nl
prefLabel
A synthetic-natural hybrid oscillator in human cells
@ast
A synthetic-natural hybrid oscillator in human cells
@en
A synthetic-natural hybrid oscillator in human cells
@nl
P2093
P2860
P356
P1476
A synthetic-natural hybrid oscillator in human cells
@en
P2093
Caroline Mock
Galit Lahav
Jared E Toettcher
P2860
P304
17047-17052
P356
10.1073/PNAS.1005615107
P407
P577
2010-09-13T00:00:00Z