Effects of outer mouth mutations on hERG channel function: a comparison with similar mutations in the Shaker channel.
about
New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1Redox state dependency of HERGS631C channel pharmacology: relation to C-type inactivation.Novel characteristics of a trafficking-defective G572R-hERG channel linked to hereditary long QT syndrome.The Eag domain regulates the voltage-dependent inactivation of rat Eag1 K+ channels.Ion conduction through the hERG potassium channel.Probing the outer mouth structure of the HERG channel with peptide toxin footprinting and molecular modeling.Extracellular sodium interacts with the HERG channel at an outer pore site.Structural and functional role of the extracellular s5-p linker in the HERG potassium channelGating charges in the activation and inactivation processes of the HERG channelProbing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic aciGating-related molecular motions in the extracellular domain of the IKs channel: implications for IKs channelopathy.Functional consequences of methionine oxidation of hERG potassium channels.Revealing the structural basis of action of hERG potassium channel activators and blockers.Na+ permeation and block of hERG potassium channels.The asparagine 533 residue in the outer pore loop region of the mouse PKD2L1 channel is essential for its voltage-dependent inactivation.Differential regulation of the slow and rapid components of guinea-pig cardiac delayed rectifier K+ channels by hypoxia.Blockade of permeation by potassium but normal gating of the G628S nonconducting hERG channel mutant.Regulation of N- and C-type inactivation of Kv1.4 by pHo and K+: evidence for transmembrane communication.Structure of the HERG K+ channel S5P extracellular linker: role of an amphipathic alpha-helix in C-type inactivation.Dynamic conformational changes of extracellular S5-P linkers in the hERG channel.Temperature dependence of human ether-a-go-go-related gene K+ currents.Linkage between 'disruption of inactivation' and 'reduction of K+ selectivity' among hERG mutants in the S5-P linker region.
P2860
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P2860
Effects of outer mouth mutations on hERG channel function: a comparison with similar mutations in the Shaker channel.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Effects of outer mouth mutatio ...... tations in the Shaker channel.
@ast
Effects of outer mouth mutatio ...... tations in the Shaker channel.
@en
Effects of outer mouth mutatio ...... tations in the Shaker channel.
@nl
type
label
Effects of outer mouth mutatio ...... tations in the Shaker channel.
@ast
Effects of outer mouth mutatio ...... tations in the Shaker channel.
@en
Effects of outer mouth mutatio ...... tations in the Shaker channel.
@nl
prefLabel
Effects of outer mouth mutatio ...... tations in the Shaker channel.
@ast
Effects of outer mouth mutatio ...... tations in the Shaker channel.
@en
Effects of outer mouth mutatio ...... tations in the Shaker channel.
@nl
P2093
P2860
P1433
P1476
Effects of outer mouth mutatio ...... tations in the Shaker channel.
@en
P2093
P2860
P304
P356
10.1016/S0006-3495(99)77464-3
P407
P577
1999-06-01T00:00:00Z