Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency.
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Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell TypesIFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damageHCV-induced miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1A diverse range of gene products are effectors of the type I interferon antiviral responseGenomic views of STAT function in CD4+ T helper cell differentiationMosquito immunity against arbovirusesCellular immune response to hepatitis-C-virus in subjects without viremia or seroconversion: is it important?Medical case reports in the age of genomic medicineSevere infectious diseases of childhood as monogenic inborn errors of immunityInborn errors of human STAT1: allelic heterogeneity governs the diversity of immunological and infectious phenotypesPrimary immunodeficiencies of pattern recognition receptorsMendelian susceptibility to mycobacterial disease: genetic, immunological, and clinical features of inborn errors of IFN-γ immunityBacillus Calmette-Guérin (BCG) complications associated with primary immunodeficiency diseasesDiscovery of single-gene inborn errors of immunity by next generation sequencingInduction and function of type I and III interferon in response to viral infectionToll-like receptors in antiviral innate immunityRecent molecular insights into rickettsial pathogenesis and immunityNatural Killer Cell Sensing of Infected Cells Compensates for MyD88 Deficiency but Not IFN-I Activity in Resistance to Mouse CytomegalovirusInducible, dose-adjustable and time-restricted reconstitution of STAT1 deficiency in vivoTranscriptional Activation of Interferon-Stimulated Genes but Not of Cytokine Genes after Primary Infection of Rhesus Macaques with Dengue Virus Type 1Interferon-inducible antiviral effectorsAn evolutionary conserved function of the JAK-STAT pathway in anti-dengue defenseInnate antiviral immunity in DrosophilaThe Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal FoldUnbalanced Immune System: Immunodeficiencies and AutoimmunityHuman IFNAR2 deficiency: Lessons for antiviral immunitySTAT2 deficiency and susceptibility to viral illness in humansHuman TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndromeHigh throughput screening for small molecule enhancers of the interferon signaling pathway to drive next-generation antiviral drug discoveryCell-Based Screen Identifies Human Interferon-Stimulated Regulators of Listeria monocytogenes InfectionInfluenza virus non-structural protein 1 (NS1) disrupts interferon signalingThe TB pandemic: an old problem seeking new solutions.A novel form of cell type-specific partial IFN-gammaR1 deficiency caused by a germ line mutation of the IFNGR1 initiation codon.Immune Escape via a Transient Gene Expression Program Enables Productive Replication of a Latent Pathogen.Novel STAT1 alleles in otherwise healthy patients with mycobacterial disease.The landscape of human proteins interacting with viruses and other pathogens.Clinical correlates of herpes simplex virus viremia among hospitalized adultsSelective inhibition of IFNG-induced autophagy by Mir155- and Mir31-responsive WNT5A and SHH signalingB cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans.Herpes simplex type I (HSV-1) infection of the nervous system: is an immune response a good thing?
P2860
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P2860
Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency.
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Impaired response to interfero ...... ase in human STAT1 deficiency.
@ast
Impaired response to interfero ...... ase in human STAT1 deficiency.
@en
Impaired response to interfero ...... ase in human STAT1 deficiency.
@nl
type
label
Impaired response to interfero ...... ase in human STAT1 deficiency.
@ast
Impaired response to interfero ...... ase in human STAT1 deficiency.
@en
Impaired response to interfero ...... ase in human STAT1 deficiency.
@nl
prefLabel
Impaired response to interfero ...... ase in human STAT1 deficiency.
@ast
Impaired response to interfero ...... ase in human STAT1 deficiency.
@en
Impaired response to interfero ...... ase in human STAT1 deficiency.
@nl
P2093
P50
P356
P1433
P1476
Impaired response to interfero ...... ase in human STAT1 deficiency.
@en
P2093
Abdulaziz Al Ghonaium
Claire Fieschi
Céline Eidenschenk
Hassan Al-Rayes
Haysam Tufenkeji
Husn Frayha
Ibrahim Zaid Al-Mohsen
Ion Gresser
Pierre Eid
P2888
P304
P356
10.1038/NG1097
P407
P577
2003-02-18T00:00:00Z