The genetics and physiology of polycystic kidney disease.
about
A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexesRetinoic acid-dependent activation of the polycystic kidney disease-1 (PKD1) promoterInversin forms a complex with catenins and N-cadherin in polarized epithelial cells.Polycystin-1 cleavage and the regulation of transcriptional pathwaysCystin localizes to primary cilia via membrane microdomains and a targeting motif.Evidence for a "Pathogenic Triumvirate" in Congenital Hepatic Fibrosis in Autosomal Recessive Polycystic Kidney DiseaseGlomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1The retinitis pigmentosa 1 protein is a photoreceptor microtubule-associated proteinAcceleration of polycystic kidney disease progression in cpk mice carrying a deletion in the homeodomain protein Cux1Activation of Trpv4 reduces the hyperproliferative phenotype of cystic cholangiocytes from an animal model of ARPKD.The cell biology of polycystic kidney diseasePolycystic kidney disease and cancer after renal transplantation.Drosophila Pkd2 is haploid-insufficient for mediating optimal smooth muscle contractility.Protein kinase D-mediated phosphorylation of polycystin-2 (TRPP2) is essential for its effects on cell growth and calcium channel activity.Primary cilia in pancreatic development and disease.Chloride channels in the kidney: lessons learned from knockout animals.Biliary dysgenesis in the PCK rat, an orthologous model of autosomal recessive polycystic kidney diseaseOuabain activates the Na-K-ATPase signalosome to induce autosomal dominant polycystic kidney disease cell proliferation.Murine models of polycystic kidney disease: molecular and therapeutic insights.Fibrocystin/polyductin, found in the same protein complex with polycystin-2, regulates calcium responses in kidney epithelia.Ginkgolide B inhibits renal cyst development in in vitro and in vivo cyst models.Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease.Essential role of cleavage of Polycystin-1 at G protein-coupled receptor proteolytic site for kidney tubular structure.Endogenous concentrations of ouabain act as a cofactor to stimulate fluid secretion and cyst growth of in vitro ADPKD models via cAMP and EGFR-Src-MEK pathways.Phosphodiesterase Isoform Regulation of Cell Proliferation and Fluid Secretion in Autosomal Dominant Polycystic Kidney Disease.Hyperproliferation of PKD1 cystic cells is induced by insulin-like growth factor-1 activation of the Ras/Raf signalling system.STIM1fl/fl Ksp-Cre Mouse has Impaired Renal Water BalanceA review on renal toxicity profile of common abusive drugs.Purinergic signaling in the lumen of a normal nephron and in remodeled PKD encapsulated cysts.Smac-mimetic-induced epithelial cell death reduces the growth of renal cysts.Regulation of cell proliferation and differentiation in the kidney.Inhibition of Comt with tolcapone slows progression of polycystic kidney disease in the more severely affected PKD/Mhm (cy/+) substrain of the Hannover Sprague-Dawley rat.Epidermal growth factor-mediated proliferation and sodium transport in normal and PKD epithelial cells.Role of cilia in normal pancreas function and in diseased states.Developmental signaling: does it bridge the gap between cilia dysfunction and renal cystogenesis?The polycystic kidney disease-1 promoter is a target of the beta-catenin/T-cell factor pathway.Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signalingIdentification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localization of polycystin-2 in vivo and in vitro.Primary Cilia in Cystic Kidney Disease.The polycystin-1 C-terminal fragment triggers branching morphogenesis and migration of tubular kidney epithelial cells.
P2860
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P2860
The genetics and physiology of polycystic kidney disease.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The genetics and physiology of polycystic kidney disease.
@ast
The genetics and physiology of polycystic kidney disease.
@en
The genetics and physiology of polycystic kidney disease.
@nl
type
label
The genetics and physiology of polycystic kidney disease.
@ast
The genetics and physiology of polycystic kidney disease.
@en
The genetics and physiology of polycystic kidney disease.
@nl
prefLabel
The genetics and physiology of polycystic kidney disease.
@ast
The genetics and physiology of polycystic kidney disease.
@en
The genetics and physiology of polycystic kidney disease.
@nl
P356
P1476
The genetics and physiology of polycystic kidney disease.
@en
P2093
Grantham JJ
P304
P356
10.1053/SNEP.2001.20929
P577
2001-03-01T00:00:00Z