Ionic currents in the human serotonin transporter reveal inconsistencies in the alternating access hypothesis
about
A current view of serotonin transporters4-(4-(dimethylamino)phenyl)-1-methylpyridinium (APP+) is a fluorescent substrate for the human serotonin transporter.Transmembrane domain 6 of the human serotonin transporter contributes to an aqueously accessible binding pocket for serotonin and the psychostimulant 3,4-methylene dioxymethamphetamine.A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transportUnifying concept of serotonin transporter-associated currentsGLT-1 Transport Stoichiometry Is Constant at Low and High Glutamate Concentrations when Chloride Is Substituted by Gluconate.Evidence for change in current-flux coupling of GLT1 at high glutamate concentrations in rat primary forebrain neurons and GLT1a-expressing COS-7 cellsMolecular mechanism of ion-ion and ion-substrate coupling in the Na+-dependent leucine transporter LeuT.Control of ion selectivity in LeuT: two Na+ binding sites with two different mechanismsTargeting the human serotonin transporter (hSERT) with quantum dots.Evidence for a role of transporter-mediated currents in the depletion of brain serotonin induced by serotonin transporter substrates.Chloride requirement for monoamine transportersElectrophysiological Actions of Synthetic Cathinones on Monoamine Transporters.'Second-generation' mephedrone analogs, 4-MEC and 4-MePPP, differentially affect monoamine transporter function.The conserved glutamate (Glu136) in transmembrane domain 2 of the serotonin transporter is required for the conformational switch in the transport cycle.A quantitative model of amphetamine action on the 5-HT transporter.The conservative view: is it necessary to implant a stent into the dopamine transporter?Alternating carrier models of asymmetric glucose transport violate the energy conservation laws.Zinc potentiates an uncoupled anion conductance associated with the dopamine transporter.The evolutionarily conserved residue A653 plays a key role in HERG channel closing.A kinetic account for amphetamine-induced monoamine release.
P2860
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P2860
Ionic currents in the human serotonin transporter reveal inconsistencies in the alternating access hypothesis
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Ionic currents in the human se ...... alternating access hypothesis
@ast
Ionic currents in the human se ...... alternating access hypothesis
@en
Ionic currents in the human se ...... alternating access hypothesis
@nl
type
label
Ionic currents in the human se ...... alternating access hypothesis
@ast
Ionic currents in the human se ...... alternating access hypothesis
@en
Ionic currents in the human se ...... alternating access hypothesis
@nl
prefLabel
Ionic currents in the human se ...... alternating access hypothesis
@ast
Ionic currents in the human se ...... alternating access hypothesis
@en
Ionic currents in the human se ...... alternating access hypothesis
@nl
P2860
P1433
P1476
Ionic currents in the human se ...... alternating access hypothesis
@en
P2093
Louis J DeFelice
Scott V Adams
P2860
P304
P356
10.1016/S0006-3495(03)74587-1
P407
P577
2003-09-01T00:00:00Z