An overview of the key routes to the best selling 5-membered ring heterocyclic pharmaceuticals.
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An overview of the synthetic routes to the best selling drugs containing 6-membered heterocyclesDiversity-oriented synthetic strategy for developing a chemical modulator of protein-protein interactionVisible light mediated intermolecular [3 + 2] annulation of cyclopropylanilines with alkynes.Rational ligand design for the arylation of hindered primary amines guided by reaction progress kinetic analysis.Synthesis and cytotoxicity studies of 1-propenyl-1,3-dihydro-benzimidazol-2-one.A bulky biaryl phosphine ligand allows for palladium-catalyzed amidation of five-membered heterocycles as electrophilesExpedient synthesis of electronically modified luciferins for bioluminescence imagingIn-Depth Assessment of the Palladium-Catalyzed Fluorination of Five-Membered Heteroaryl Bromides.Suzuki-Miyaura cross-coupling of unprotected, nitrogen-rich heterocycles: substrate scope and mechanistic investigation.Direct Assembly of Prenylated Heteroarenes through a Cascade Minisci Reaction/Dehydration Sequence.Synthesis of heterocyclic triads by Pd-catalyzed cross-couplings and evaluation of their cell-specific toxicity profile.Palladium-catalyzed amination of unprotected five-membered heterocyclic bromides4-isoxazolyl-1,4-dihydropyridines: a tale of two scaffolds.Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors.Transition metal-free one-pot synthesis of nitrogen-containing heterocycles.Modern advances in heterocyclic chemistry in drug discovery.Applications of Palladium-Catalyzed C-N Cross-Coupling Reactions.From Lead to Drug Utilizing a Mannich Reaction: The Topotecan Story.Recent advances in the tandem reaction of azides with alkynes or alkynols.Syntheses of 3,4- and 1,4-dihydroquinazolines from 2-aminobenzylamine.Microwave-assisted cyclizations promoted by polyphosphoric acid esters: a general method for 1-aryl-2-iminoazacycloalkanes.A palladium-catalyzed synthesis of (hetero)aryl-substituted imidazoles from aryl halides, imines and carbon monoxide.Thiazole formation through a modified Gewald reaction.Ynamide carbopalladation: a flexible route to mono-, bi- and tricyclic azacycles.A structure-activity relationship study on multi-heterocyclic molecules: two linked thiazoles are required for cytotoxic activity.Iridium(iii) complexes with five-membered heterocyclic ligands for combined photodynamic therapy and photoactivated chemotherapy.Catalytic formal [2+2+1] synthesis of pyrroles from alkynes and diazenes via Ti(II)/Ti(IV) redox catalysis.A concise flow synthesis of indole-3-carboxylic ester and its derivatisation to an auxin mimic.A one-pot route to thioamides discovered by gas-phase studies: palladium-mediated CO2 extrusion followed by insertion of isothiocyanates.Palladium-catalyzed regioselective C-H fluoroalkylation of indoles at the C4-position.Trichloromethylthiolation of N-Heterocycles: Practical and Completely Regioselective.Organocatalytic [3 + 2] cycloaddition of oxindole-based azomethine ylides with 3-nitrochromenes: a facile approach to enantioenriched polycyclic spirooxindole-chromane adducts.A green, multicomponent, regio- and stereo-selective 1,3-dipolar cycloaddition of azides and azomethine ylides generated in situ with bifunctional dipolarophiles using PEG-400.Solvent- and catalyst-free huisgen cycloaddition to rufinamide in flow with a greener, less expensive dipolarophile.Enantioselective Aza Michael-Type Addition to Alkenyl Benzimidazoles Catalyzed by a Chiral Phosphoric Acid.Development of Gold-catalyzed [4+1] and [2+2+1]/[4+2] Annulations between Propiolate Derivatives and Isoxazoles.Metal-free nitrative cyclization of N-aryl imines with tert-butyl nitrite: dehydrogenative access to 3-nitroindoles.Pressure-accelerated azide-alkyne cycloaddition: micro capillary versus autoclave reactor performance.Synthesis and Biological Evaluation of Novel 1-(4-(Hydroxy(1-oxo-1,3-dihydro-2H-inden-2-ylidene)methyl)phenyl)-3-phenylurea Derivatives.Probing the hydrolytic reactivity of 2-difluoromethyl pyrroles.
P2860
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P2860
An overview of the key routes to the best selling 5-membered ring heterocyclic pharmaceuticals.
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
An overview of the key routes ...... heterocyclic pharmaceuticals.
@ast
An overview of the key routes ...... heterocyclic pharmaceuticals.
@en
An overview of the key routes ...... heterocyclic pharmaceuticals.
@nl
type
label
An overview of the key routes ...... heterocyclic pharmaceuticals.
@ast
An overview of the key routes ...... heterocyclic pharmaceuticals.
@en
An overview of the key routes ...... heterocyclic pharmaceuticals.
@nl
altLabel
An overview of the key routes ...... g heterocyclic pharmaceuticals
@en
prefLabel
An overview of the key routes ...... heterocyclic pharmaceuticals.
@ast
An overview of the key routes ...... heterocyclic pharmaceuticals.
@en
An overview of the key routes ...... heterocyclic pharmaceuticals.
@nl
P2860
P50
P356
P1476
An overview of the key routes ...... heterocyclic pharmaceuticals.
@en
P2093
Nikzad Nikbin
P2860
P304
P356
10.3762/BJOC.7.57
P407
P577
2011-04-18T00:00:00Z