Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.
about
ADAM and ADAMTS Family Proteins and Snake Venom Metalloproteinases: A Structural OverviewDisappearing acts of ADAMTS13Proteolytic processing of von Willebrand factor by adamts13 and leukocyte proteasesAnimal models for thrombotic thrombocytopenic purpuraThe unfolded von Willebrand factor response in bloodstream: the self-association perspectiveStructural basis of type 2A von Willebrand disease investigated by molecular dynamics simulations and experimentsvon Willebrand factor: more than a regulator of hemostasis and thrombosis.ADAMTS13 unbound to larger von Willebrand factor multimers in cryosupernatant: implications for selection of plasma preparations for thrombotic thrombocytopenic purpura treatment.Crystal structure and enzymatic activity of an ADAMTS-13 mutant with the East Asian-specific P475S polymorphism.Conformational activation of ADAMTS13.Reduced ADAMTS13 activity is associated with thrombotic risk in systemic lupus erythematosus.Thrombotic microangiopathy caused by severe graft dysfunction after living donor liver transplantation: report of a case.ADAMTS13 and von Willebrand factor interactions.A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malariaADAMTS13 and anti-ADAMTS13 autoantibodies in thrombotic thrombocytopenic purpura - current perspectives and new treatment strategies.Regulation of VWF expression, and secretion in health and disease.A model for the conformational activation of the structurally quiescent metalloprotease ADAMTS13 by von Willebrand factor.ADAMTS13 controls vascular remodeling by modifying VWF reactivity during stroke recovery.Von Willebrand Factor as a Novel Player in Valvular Heart Disease: From Bench to Valve Replacement.The role of the ADAMTS13 cysteine-rich domain in VWF binding and proteolysis.Von Willebrand factor, a versatile player in gastrointestinal bleeding in left ventricular assist device recipients?Probing ADAMTS13 substrate specificity using phage displayDetection of Plasma Protease Activity Using Microsphere-Cytometry Assays with E. coli Derived Substrates: VWF Proteolysis by ADAMTS13Hyperglycemia repression of miR-24 coordinately upregulates endothelial cell expression and secretion of von Willebrand factor.Massively parallel enzyme kinetics reveals the substrate recognition landscape of the metalloprotease ADAMTS13.Protective anti-inflammatory effect of ADAMTS13 on myocardial ischemia/reperfusion injury in mice.Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS-13.The role of ADAMTS13 in acute myocardial infarction: cause or consequence?Control of VWF A2 domain stability and ADAMTS13 access to the scissile bond of full-length VWF.von Willebrand factor: at the crossroads of bleeding and thrombosis.von Willebrand factor: the old, the new and the unknown.On the versatility of von Willebrand factorMicrovascular platforms for the study of platelet-vessel wall interactions.Fluid Mechanics of Blood Clot Formation.Role of fluid shear stress in regulating VWF structure, function and related blood disorders.The Role of von Willebrand Factor in Vascular Inflammation: From Pathogenesis to Targeted Therapy.Diagnostic approach to microangiopathic hemolytic disorders.Angiodysplasia in von Willebrand Disease: Understanding the Clinical and Basic Science.N-linked glycan stabilization of the VWF A2 domainConformational quiescence of ADAMTS-13 prevents proteolytic promiscuity.
P2860
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P2860
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.
@ast
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.
@en
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.
@nl
type
label
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.
@ast
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.
@en
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.
@nl
prefLabel
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.
@ast
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.
@en
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.
@nl
P2860
P50
P1433
P1476
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor
@en
P2093
David A Lane
P2860
P304
P356
10.1182/BLOOD-2011-02-306597
P407
P577
2011-06-29T00:00:00Z