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ADAMTS13 substrate recognition of von Willebrand factor A2 domainVessel wall BAMBI contributes to hemostasis and thrombus stability.Plasma ADAMTS-13 levels and the risk of myocardial infarction: an individual patient data meta-analysis.Blocking VWF platelet binding to treat TTP.Conformational activation of ADAMTS13.Pathogenicity of Anti-ADAMTS13 Autoantibodies in Acquired Thrombotic Thrombocytopenic Purpura.Activated protein C cofactor function of protein S: a critical role for Asp95 in the EGF1-like domainThe importance of vicinal cysteines, C1669 and C1670, for von Willebrand factor A2 domain functionDisruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality.Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.Mechanism of von Willebrand factor scissile bond cleavage by a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13).The role of the ADAMTS13 cysteine-rich domain in VWF binding and proteolysis.Protective effects of non-anticoagulant activated protein C variant (D36A/L38D/A39V) in a murine model of ischaemic stroke.Evidence that high von Willebrand factor and low ADAMTS-13 levels independently increase the risk of a non-fatal heart attackThe haemostatic role of tissue factor pathway inhibitor.The ADAMTS13 metalloprotease domain: roles of subsites in enzyme activity and specificity.TFPI cofactor function of protein S: essential role of the protein S SHBG-like domainFactor V has an anticoagulant cofactor activity that targets the early phase of coagulation.Essential role of the disintegrin-like domain in ADAMTS13 function.Reduced body weight and increased postimplantation fetal death in tyrosylprotein sulfotransferase-1-deficient mice.Proteolytic inactivation of ADAMTS13 by thrombin and plasmin.Differential expression of Toll-like receptors in follicular lymphoma, diffuse large B-cell lymphoma and peripheral T-cell lymphoma.Proteomic discovery of substrates of the cardiovascular protease ADAMTS7Cytoprotective effect of activated protein C: specificity of PAR-1 signalingHigh VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young womenRole of a 5'-enhancer in the transcriptional regulation of the human endothelial cell protein C receptor geneCardiovascular string theoryThrombomodulin analogues for the treatment of ischemic strokeActivated protein C cofactor function of protein S: a novel role for a γ-carboxyglutamic acid residueCirculating ADAMTS-13-von Willebrand factor complexes: an enzyme on demandIdentification of functionally important residues in TFPI Kunitz domain 3 required for the enhancement of its activity by protein SDetection of anti-platelet antibodies in immune thrombocytopenia by flow cytometryActivated αIIbβ3 on platelets mediates flow-dependent NETosis via SLC44A2Defective fibrin deposition and thrombus stability in Bambi-/- mice are mediated by elevated anticoagulant functionThe roles of factor Va and protein S in formation of the activated protein C/protein S/factor Va inactivation complexCrystal structure and substrate-induced activation of ADAMTS13
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P50
description
researcher
@en
name
James T B Crawley
@en
James T B Crawley
@nl
type
label
James T B Crawley
@en
James T B Crawley
@nl
prefLabel
James T B Crawley
@en
James T B Crawley
@nl
P106
P31
P496
0000-0002-6723-7841