DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS gene.
about
DNA polymerase family X: function, structure, and cellular rolesOverexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugsInhibition of double-strand break non-homologous end-joining by cisplatin adducts in human cell extractsStructural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4Enhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor agentsHuman DNA polymerase lambda functionally and physically interacts with proliferating cell nuclear antigen in normal and translesion DNA synthesisThe structural basis of XRCC1-mediated DNA repairSpecific interaction of DNA polymerase beta and DNA ligase I in a multiprotein base excision repair complex from bovine testisStructural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: towards the design of higher-affinity inhibitors.DNA polymerase β contains a functional nuclear localization signal at its N-terminus.Effect of manganese on in vitro replication of damaged DNA catalyzed by the herpes simplex virus type-1 DNA polymerase.Structural basis for the inefficient nucleotide incorporation opposite cisplatin-DNA lesion by human DNA polymerase β.Selective recognition of a cisplatin-DNA adduct by human mismatch repair proteins.Strategic down-regulation of DNA polymerase beta by antisense RNA sensitizes mammalian cells to specific DNA damaging agents.Clinical significance of a point mutation in DNA polymerase beta (POLB) gene in gastric cancerMutator phenotypes due to DNA replication infidelity.Real-time surface plasmon resonance study of biomolecular interactions between polymerase and bulky mutagenic DNA lesions.The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase beta and increases its DNA substrate utilisation efficiency: implications for DNA repairMolecular mechanisms of resistance and toxicity associated with platinating agents.Effects of base excision repair gene polymorphisms on pancreatic cancer survivalFork-like DNA templates support bypass replication of lesions that block DNA synthesis on single-stranded templates.Bypass of a psoralen DNA interstrand cross-link by DNA polymerases β, ι, and κ in vitro.Mechanism of double-base lesion bypass catalyzed by a Y-family DNA polymerase.A comprehensive survey of the mutagenic impact of common cancer cytotoxicsNon-DNA-binding platinum anticancer agents: Cytotoxic activities of platinum-phosphato complexes towards human ovarian cancer cellsChemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.Replication, repair, and translesion polymerase bypass of N⁶-oxopropenyl-2'-deoxyadenosine.Translesion DNA synthesis in the context of cancer research.Energetics and specificity of Rat DNA polymerase beta interactions with template-primer and gapped DNA substrates.DNA Polymerase Beta Germline Variant Confers Cellular Response to Cisplatin Therapy.Replication across O6-methylguanine by human DNA polymerase beta in vitro. Insights into the futile cytotoxic repair and mutagenesis of O6-methylguanine.Aberrant Kynurenine Signaling Modulates DNA Replication Stress Factors and Promotes Genomic Instability in Gliomas.Ataxia telangiectasia and rad3-related kinase contributes to cell cycle arrest and survival after cisplatin but not oxaliplatin.Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity.Recognition of DNA alterations by the mismatch repair systemAcquired resistance of pancreatic cancer cells to cisplatin is multifactorial with cell context-dependent involvement of resistance genes.In vitro bypass replication of the cisplatin-d(GpG) lesion by calf thymus DNA polymerase beta and human immunodeficiency virus type I reverse transcriptase is highly mutagenic.Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug.Structural and Kinetic Studies of the Effect of Guanine N7 Alkylation and Metal Cofactors on DNA Replication
P2860
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P2860
DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS gene.
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
DNA polymerase beta bypasses in vitro a single d
@nl
DNA polymerase beta bypasses i ...... on codon 13 of the HRAS gene.
@ast
DNA polymerase beta bypasses i ...... on codon 13 of the HRAS gene.
@en
type
label
DNA polymerase beta bypasses in vitro a single d
@nl
DNA polymerase beta bypasses i ...... on codon 13 of the HRAS gene.
@ast
DNA polymerase beta bypasses i ...... on codon 13 of the HRAS gene.
@en
prefLabel
DNA polymerase beta bypasses in vitro a single d
@nl
DNA polymerase beta bypasses i ...... on codon 13 of the HRAS gene.
@ast
DNA polymerase beta bypasses i ...... on codon 13 of the HRAS gene.
@en
P2093
P2860
P356
P1476
DNA polymerase beta bypasses i ...... on codon 13 of the HRAS gene.
@en
P2093
P2860
P304
P356
10.1073/PNAS.92.12.5356
P407
P577
1995-06-01T00:00:00Z