Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis. - Wikidata - awgldk - TriplyDB

Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis.

Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis.

http://www.wikidata.org/entity/Q34218789

about

Tex14, a Plk1-regulated protein, is required for kinetochore-microtubule attachment and regulation of the spindle assembly checkpoint The 3' untranslated region of the cyclin B mRNA is not sufficient to enhance the synthesis of cyclin B during a mitotic block in human cells Reduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutation Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders Reprogramming to pluripotency can conceal somatic cell chromosomal instability USP44 regulates centrosome positioning to prevent aneuploidy and suppress tumorigenesis Overexpression of ubiquitin specific protease 44 (USP44) induces chromosomal instability and is frequently observed in human T-cell leukemia Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors.Chk2 prevents mitotic exit when the majority of kinetochores are unattached.Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan.Myosin phosphatase-targeting subunit 1 controls chromatid segregation Regulated inactivation of the spindle assembly checkpoint without functional mitotic spindles.Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability Cyclin B2 and p53 control proper timing of centrosome separation Punctuated cyclin synthesis drives early embryonic cell cycle oscillations.High rates of chromosome missegregation suppress tumor progression but do not inhibit tumor initiation.2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells.Cyclin B1 mRNA translation is temporally controlled through formation and disassembly of RNA granules Phosphatases: providing safe passage through mitotic exit.Genetic instability: tipping the balance.Ubiquitin, the centrosome, and chromosome segregation.The Use of SNAP Labeling to Study Cell Cycle Oscillatory Proteins.Living in CIN: Mitotic Infidelity and Its Consequences for Tumor Promotion and Suppression.Studying proteolysis of cyclin B at the single cell level in whole cell populations.Cdc20 control of cell fate during prolonged mitotic arrest: do Cdc20 protein levels affect cell fate in response to antimitotic compounds?Mitotic Checkpoint Regulators Control Insulin Signaling and Metabolic Homeostasis.A little Cdc20 goes a long way.

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P2860

Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis.

http://www.wikidata.org/entity/Q34218789

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis.

@ast

Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis.

@en

Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis.

@nl

type

label

Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis.

@ast

Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis.

@en

Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis.

@nl

prefLabel

Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis.

@ast

Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis.

@en

Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis.

@nl

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Journal of Cell Biology

P1476

Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis

@en

P2093

Darren J Baker

http://www.w3.org/2001/XMLSchema#string

Fang Jin

http://www.w3.org/2001/XMLSchema#string

Jan M van Deursen

http://www.w3.org/2001/XMLSchema#string

Janine H van Ree

http://www.w3.org/2001/XMLSchema#string

Karthik B Jeganathan

http://www.w3.org/2001/XMLSchema#string

Liviu Malureanu

http://www.w3.org/2001/XMLSchema#string

Oliver Gullon

http://www.w3.org/2001/XMLSchema#string

Zheyan Chen

http://www.w3.org/2001/XMLSchema#string

P2860

Aurora B regulates MCAK at the mitotic centromere

A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons

CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity

The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha

The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction.

Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells

Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis

Structural activation of Mad2 in the mitotic spindle checkpoint: the two-state Mad2 model versus the Mad2 template model

Mad2 overexpression promotes aneuploidy and tumorigenesis in mice

P304

313-329

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scholarly article

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10.1083/JCB.201003090

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2

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191

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2010-10-01T00:00:00Z

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47459347

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20956380

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2958469

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