Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.
about
Protein prenyltransferasesCloning and characterization of a mammalian prenyl protein-specific proteaseThe crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimeticsUSP17 regulates Ras activation and cell proliferation by blocking RCE1 activityPosttranslationally processed structure of the human platelet protein smg p21B: evidence for geranylgeranylation and carboxyl methylation of the C-terminal cysteineInfluence of metal ions on substrate binding and catalytic activity of mammalian protein geranylgeranyltransferase type-IPrenylation of Rab8 GTPase by type I and type II geranylgeranyl transferasesInhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndromeThe exocytotic trafficking of TC10 occurs through both classical and nonclassical secretory transport pathways in 3T3L1 adipocytes.A tagging-via-substrate technology for detection and proteomics of farnesylated proteinsIsoprenoid modification of rab proteins terminating in CC or CXC motifsInactivation of Icmt inhibits transformation by oncogenic K-Ras and B-RafStructure of mammalian protein geranylgeranyltransferase type-IThe orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolismThe vacuolar DHHC-CRD protein Pfa3p is a protein acyltransferase for Vac8pPurified yeast protein farnesyltransferase is structurally and functionally similar to its mammalian counterpart.Analysis of the role of the hypervariable region of yeast Ras2p and its farnesylation in the interaction with exchange factors and adenylyl cyclase.The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins.BTS1 encodes a geranylgeranyl diphosphate synthase in Saccharomyces cerevisiae.RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins.Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene productAnalysis of prelamin A biogenesis reveals the nucleus to be a CaaX processing compartmentProtein farnesyltransferase and protein prenylation in Plasmodium falciparumRas-induced cellular events (review)Prenylation-dependent association of protein-tyrosine phosphatases PRL-1, -2, and -3 with the plasma membrane and the early endosomeInteraction of farnesylated PRL-2, a protein-tyrosine phosphatase, with the beta-subunit of geranylgeranyltransferase IIProtein prenyltransferasesThematic review series: lipid posttranslational modifications. Fighting parasitic disease by blocking protein farnesylationMating pheromones of the fission yeast Schizosaccharomyces pombe: purification and structural characterization of M-factor and isolation and analysis of two genes encoding the pheromoneEffect of insulin on farnesyltransferase activity in 3T3-L1 adipocytesLysine(164)alpha of protein farnesyltransferase is important for both CaaX substrate binding and catalysisProtein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude miceModulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmonary fibrosisCloning and identification of MYPT3: a prenylatable myosin targetting subunit of protein phosphatase 1A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in DrosophilaInhibition of protein geranylgeranylation causes a superinduction of nitric-oxide synthase-2 by interleukin-1beta in vascular smooth muscle cellsInactivation of farnesyltransferase and geranylgeranyltransferase I by caspase-3: cleavage of the common alpha subunit during apoptosisCloning and expression of a cDNA encoding the alpha subunit of rat p21ras protein farnesyltransferaseProgress in Making Ras as a Druggable TargetRas oncogenes: split personalities
P2860
Q21194871-028A60E1-6BEB-49A8-9DDB-BEE41F64CE94Q22009066-0D6F34B3-7423-485B-B00A-352324EC73BEQ24291855-3BCF1BFB-63C4-4F29-9C88-8317BD1EFE74Q24328791-74DE0AEE-293E-47E2-B9E8-C72E01BEADC7Q24337045-BB7EECFB-CDA4-4904-A28E-45AE9B3DCF1BQ24530008-927016B6-31DE-401B-8DDF-860593B282C9Q24531139-9A52183D-7C6F-45FD-8B56-148CBEC60675Q24531946-4AFA2B15-0A54-4348-85CD-940514ED00E4Q24540862-FB086E53-D78C-4115-9804-A585DB3BA047Q24562961-C0126B50-3CBB-49C7-8974-3E832732935BQ24564341-CA6FB65F-5BB9-4CCE-BE86-CB0630EC12ECQ24598824-1E4B403C-DBDB-45FA-83DD-07EE0AB0AE4DQ24644688-2B822930-1DA8-409E-986E-54764801F3DAQ24657371-51236834-C86D-45BA-BBB0-35133EF14E57Q24678955-3C20809B-F507-47DB-9F1A-6E74DFFA1414Q27929835-6099D5A1-B4CE-4C14-BE4D-2FD8E88273F1Q27932252-31DF7E82-6DB2-4C37-A1BB-DE2AB4347F8FQ27935631-AF0FD238-750F-4B86-8348-9BFD3B19DF72Q27936313-EE964981-A676-4A80-AB70-99DA4912E53EQ27936473-FCB2ECB0-A6B0-4ECA-A182-E37C60FC6D97Q27937733-A84C52A4-C3BE-4696-8790-C45F595A85ADQ27939423-6149D22A-1C4D-45F2-8104-04C3DBDA3A61Q27973925-5700842B-0E96-4CCC-A520-29A4E64FB51AQ28138814-1FCC1536-AB82-4F2A-BC79-1B3100FC691EQ28140543-B52661E6-BC12-41CD-853E-744E6FA6566CQ28205756-0BF8DBE0-7509-48B4-81BB-9CB99B319C4CQ28277579-47A0C38C-2446-421C-8075-A91CE085199EQ28285888-13C31D39-9DE7-4E01-888D-947B96DDBD59Q28287378-F42DC5D0-B664-440C-B41F-6BE0D93EC10CQ28296170-33FB8CB8-B083-4E2E-B5D3-9653A2E63C3BQ28365851-DFD513EB-EFBE-45BD-A187-E3D85D188128Q28369454-0D10B82E-26BC-4503-8047-0AB21BA2AF8BQ28385018-415E3542-B7F1-44D2-AEE5-ED2E145F5CC0Q28511633-B6F40DAC-29F2-44B6-BACA-7448C6EA323AQ28541015-3059844A-A7ED-49BC-AB28-F0B9351FC7CBQ28567450-7914E7BB-C0C4-4736-B951-15C600C2AB67Q28580707-F5A90E84-30BE-42D5-AB4D-D24C232A11F6Q28581840-E95B977C-53E8-4DB6-9D2F-422E4FB3C5D2Q28610567-2814C7AE-756B-4146-9732-706CCC4F0622Q29615405-899D680E-5C6B-41FD-9E5E-B51A76FCF08D
P2860
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.
description
1990 nî lūn-bûn
@nan
1990 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.
@ast
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.
@en
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.
@nl
type
label
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.
@ast
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.
@en
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.
@nl
prefLabel
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.
@ast
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.
@en
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.
@nl
P2093
P1433
P1476
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.
@en
P2093
P356
10.1016/0092-8674(90)90242-7
P407
P577
1990-07-01T00:00:00Z