Nuclear export of ERK3 by a CRM1-dependent mechanism regulates its inhibitory action on cell cycle progression. - Wikidata - awgldk - TriplyDB

Nuclear export of ERK3 by a CRM1-dependent mechanism regulates its inhibitory action on cell cycle progression.

Nuclear export of ERK3 by a CRM1-dependent mechanism regulates its inhibitory action on cell cycle progression.

http://www.wikidata.org/entity/Q34221836

about

Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway N-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasome Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases The pheromone-induced nuclear accumulation of the Fus3 MAPK in yeast depends on its phosphorylation state and on Dig1 and Dig2.Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway Scaffolding by ERK3 regulates MK5 in development Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5 Physiological roles of mitogen-activated-protein-kinase-activated p38-regulated/activated protein kinase Homology modeling and ligand docking of Mitogen-activated protein kinase-activated protein kinase 5 (MK5).A computational framework for boosting confidence in high-throughput protein-protein interaction datasets Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors Increased sinusoidal flow is not the primary stimulus to liver regeneration.Administration of antenatal glucocorticoids and postnatal surfactant ameliorates respiratory distress syndrome-associated neonatal lethality in Erk3(-/-) mouse pups.Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions Targeted inactivation of Mapk4 in mice reveals specific nonredundant functions of Erk3/Erk4 subfamily mitogen-activated protein kinases.Identification of the atypical MAPK Erk3 as a novel substrate for p21-activated kinase (Pak) activity ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion.A novel role for atypical MAPK kinase ERK3 in regulating breast cancer cell morphology and migration A novel mechanism for mitogen-activated protein kinase localization PIP degron proteins, substrates of CRL4Cdt2, and not PIP boxes, interfere with DNA polymerase η and κ focus formation on UV damage Cross-talk between protein kinase A and the MAPK-activated protein kinases RSK1 and MK5.Tumour promoting and suppressing roles of the atypical MAP kinase signalling pathway ERK3/4-MK5 A novel phenoxy thiophene sulphonamide molecule protects against glutamate evoked oxidative injury in a neuronal cell model Identification of MMP-15 as an anti-apoptotic factor in cancer cells.Analysis of ERK3 intracellular localization: dynamic distribution during mitosis and apoptosis ERK3 promotes endothelial cell functions by upregulating SRC-3/SP1-mediated VEGFR2 expression.Serine residue 115 of MAPK-activated protein kinase MK5 is crucial for its PKA-regulated nuclear export and biological function.MicroRNA-26a targets MAPK6 to inhibit smooth muscle cell proliferation and vein graft neointimal hyperplasia.Proteomic and bioinformatic analysis of epithelial tight junction reveals an unexpected cluster of synaptic molecules.C-terminal domain phosphorylation of ERK3 controlled by Cdk1 and Cdc14 regulates its stability in mitosis.L290P/V mutations increase ERK3's cytoplasmic localization and migration/invasion-promoting capability in cancer cells.MAPK4;6 translocate to nucleus MAPK4;6 translocate to the cytoplasm MAPK6 binds CCND3 Regulation of MAPK-activated protein kinase 5 activity and subcellular localization by the atypical MAPK ERK4/MAPK4.The atypical mitogen-activated protein kinase ERK3 is essential for establishment of epithelial architecture.

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P2860

Nuclear export of ERK3 by a CRM1-dependent mechanism regulates its inhibitory action on cell cycle progression.

http://www.wikidata.org/entity/Q34221836

description

2003 nî lūn-bûn

@nan

2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի օգոստոսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Nuclear export of ERK3 by a CR ...... ion on cell cycle progression.

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Nuclear export of ERK3 by a CR ...... ion on cell cycle progression.

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Nuclear export of ERK3 by a CR ...... ion on cell cycle progression.

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Nuclear export of ERK3 by a CR ...... ion on cell cycle progression.

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Nuclear export of ERK3 by a CR ...... ion on cell cycle progression.

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Nuclear export of ERK3 by a CR ...... ion on cell cycle progression.

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Nuclear export of ERK3 by a CR ...... ion on cell cycle progression.

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Nuclear export of ERK3 by a CR ...... ion on cell cycle progression.

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Nuclear export of ERK3 by a CR ...... ion on cell cycle progression.

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P1433

Journal of Biological Chemistry

P1476

Nuclear export of ERK3 by a CR ...... ion on cell cycle progression.

@en

P2093

Catherine Julien

http://www.w3.org/2001/XMLSchema#string

Philippe Coulombe

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Sylvain Meloche

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P2860

Interaction of mitogen-activated protein kinases with the kinase interaction motif of the tyrosine phosphatase PTP-SL provides substrate specificity and retains ERK2 in the cytoplasm

T RANSPORT B ETWEEN THE C ELL N UCLEUS AND THE C YTOPLASM

Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm

Phosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST)

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

Snurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structure

Cloning and characterization of p97MAPK, a novel human homolog of rat ERK-3

Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex

Nuclear localization and regulation of erk- and rsk-encoded protein kinases

CRM1-mediated recycling of snurportin 1 to the cytoplasm

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42615-42624

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10.1074/JBC.M302724200

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43

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278

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2003-08-12T00:00:00Z

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12915405

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