Molecular identification and functional roles of a Ca(2+)-activated K+ channel in human and mouse hearts.
about
Alpha-actinin2 cytoskeletal protein is required for the functional membrane localization of a Ca2+-activated K+ channel (SK2 channel)Analysis of Single Nucleotide Polymorphisms (SNPs) of the small-conductance calcium activated potassium channel (SK3) gene as genetic modifier of the cardiac phenotype in myotonic dystrophy type 1 patientsAn amino acid outside the pore region influences apamin sensitivity in small conductance Ca2+-activated K+ channelsMechanisms underlying the cardiac pacemaker: the role of SK4 calcium-activated potassium channelsThe role of action potential alternans in the initiation of atrial fibrillation in humans: a review and future directionsIon Channels in the HeartSmall-conductance Ca2+ -activated K+ channels and cardiac arrhythmiasAmiodarone inhibits apamin-sensitive potassium currentsIdentification of the functional binding pocket for compounds targeting small-conductance Ca2+-activated potassium channelsUnstructured to structured transition of an intrinsically disordered protein peptide in coupling Ca2+-sensing and SK channel activationSK channels and ventricular arrhythmias in heart failureFunctional interaction with filamin A and intracellular Ca2+ enhance the surface membrane expression of a small-conductance Ca2+-activated K+ (SK2) channelAblation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillationDifferential expression of small-conductance Ca2+-activated K+ channels SK1, SK2, and SK3 in mouse atrial and ventricular myocytesArrhythmogenic calmodulin mutations impede activation of small-conductance calcium-activated potassium currentAlternative splice isoforms of small conductance calcium-activated SK2 channels differ in molecular interactions and surface levelsKCNN2 polymorphisms and cardiac tachyarrhythmias.Apamin does not inhibit human cardiac Na+ current, L-type Ca2+ current or other major K+ currentsExercise training reduces resting heart rate via downregulation of the funny channel HCN4Common variants in KCNN3 are associated with lone atrial fibrillation.Improved understanding of the pathophysiology of atrial fibrillation through the lens of discrete pathological pathwaysCalcium-activated potassium current modulates ventricular repolarization in chronic heart failure.Apamin-sensitive calcium-activated potassium currents in rabbit ventricles with chronic myocardial infarction.Genome-wide association studies of atrial fibrillation: past, present, and future.Genetics of atrial fibrillation: implications for future research directions and personalized medicine.Small-conductance calcium-activated potassium channel and recurrent ventricular fibrillation in failing rabbit ventricles.Functional, anatomical, and molecular investigation of the cardiac conduction system and arrhythmogenic atrioventricular ring tissue in the rat heart.Regulation of gene transcription by voltage-gated L-type calcium channel, Cav1.3.RyR2 modulates a Ca2+-activated K+ current in mouse cardiac myocytes.Down-regulation of the small conductance calcium-activated potassium channels in diabetic mouse atria.Targeting the Small- and Intermediate-Conductance Ca-Activated Potassium Channels: The Drug-Binding Pocket at the Channel/Calmodulin InterfaceAtrial fibrillation: current knowledge and future directions in epidemiology and genomics.Selective phosphorylation modulates the PIP2 sensitivity of the CaM-SK channel complexSmall conductance calcium-activated potassium current is important in transmural repolarization of failing human ventricles.Early electrical remodeling in rabbit pulmonary vein results from trafficking of intracellular SK2 channels to membrane sitesSmall-Conductance Calcium-Activated Potassium Current Is Activated During Hypokalemia and Masks Short-Term Cardiac Memory Induced by Ventricular PacingEpicardial adipose tissue and neural mechanisms of atrial fibrillationProtection against cardiac injury by small Ca(2+)-sensitive K(+) channels identified in guinea pig cardiac inner mitochondrial membraneSKA-31, a novel activator of SK(Ca) and IK(Ca) channels, increases coronary flow in male and female rat heartsImaging arrhythmogenic calcium signaling in intact hearts.
P2860
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P2860
Molecular identification and functional roles of a Ca(2+)-activated K+ channel in human and mouse hearts.
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
name
Molecular identification and functional roles of a Ca
@nl
Molecular identification and f ...... nel in human and mouse hearts.
@ast
Molecular identification and f ...... nel in human and mouse hearts.
@en
type
label
Molecular identification and functional roles of a Ca
@nl
Molecular identification and f ...... nel in human and mouse hearts.
@ast
Molecular identification and f ...... nel in human and mouse hearts.
@en
prefLabel
Molecular identification and functional roles of a Ca
@nl
Molecular identification and f ...... nel in human and mouse hearts.
@ast
Molecular identification and f ...... nel in human and mouse hearts.
@en
P2093
P2860
P356
P1476
Molecular identification and f ...... nel in human and mouse hearts.
@en
P2093
Ana E Vázquez
Dipika Tuteja
Ebenezer N Yamoah
Holly R Tuxson
J Nilas Young
Jennifer Rodriguez
Kathryn A Glatter
Liping Nie
Nipavan Chiamvimonvat
P2860
P304
49085-49094
P356
10.1074/JBC.M307508200
P407
P577
2003-09-17T00:00:00Z